Cinnamic acids and derivatives
Apexbio Technology LLC (E,E)-Bisdemethoxycurcumin 33171-05-0 5mg
(E E)-Bisdemethoxycurcumin (CAS 33171-05-0) is a naturally derived curcuminoid and a structural analog within the demethoxycurcumin class Research demonstrates that this compound modulates multiple inflammatory signaling pathways and alters the expression of various inflammatory mediators It has been shown to induce cell cycle arrest promote apoptosis in cancer cells and inhibit proliferation-related pathways (E E)-Bisdemethoxycurcumin is widely utilized in studies investigating the molecular mechanisms of inflammation tumor cell biology and the pharmacological properties of curcuminoid derivatives
Apexbio Technology LLC Tyrphostin A1 2826-26-8 10mg
Tyrphostin A1 (CAS 2826-26-8) is a small molecule inhibitor targeting tyrosine kinase activity specifically involved in disrupting intracellular signaling pathways in immune cells It has been shown to interfere with CD40 ligand-induced signaling resulting in suppressed interleukin-12 (IL-12) secretion by macrophages and reduced differentiation of antigen-induced T helper 1 (Th1) cells Tyrphostin A1 is widely utilized in studies investigating cell-to-cell signaling immune response modulation and the mechanisms underlying inflammatory processes particularly in the context of autoimmune disease models
TARGETMOL CHEMICALS INC REFAMETINIB R ENANTIOMER 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Refametinib R enantiomer (RDEA119 R enantiomer) is an MEK inhibitor with an EC50 of 2.0-15 nM.Refametinib (R enantiomer) has anticancer activity and can be used in cancer research. purity: 99%
Medchemexpress LLC (3Z)-2-amino-4-(4-hydroxyphenyl)buta-1,3-diene-1,1,3-tricarbonitrile | 144978-82-5 | 98.6% | 236.23 g/mol | C13H8N4O | 5 MG
Tyrphostin AG 112 is a small-molecule inhibitor of epidermal growth factor receptor (EGFR) phosphorylation used in biochemical and cellular research. The compound is supplied as a solid with high purity and is compatible with DMSO-based solutions for in vitro testing and with co-solvent formulations for in vivo studies.
- Molecular formula: C13H8N4O.
- Molecular weight: 236.23 g/mol.
- Purity: 98.6%.
- Appearance: solid.
- Solubility: DMSO soluble (125 mg/mL); in vivo co-solvent formulations give clear solutions.
- Available pack sizes: 5 mg, 10 mg, 25 mg, larger sizes by quote.
Medchemexpress LLC (2E,4E)-hexa-2,4-dien-1-ol | 17102-64-6 | MFCD00002925 | 98.8% | 98.14 g/mol | C6H10O | 1 G
(2E,4E)-Hexa-2,4-dien-1-ol is a small organic compound containing a conjugated diene and a primary alcohol. It is used as a biochemical assay reagent and reference standard in chemical research and flavor/aroma studies. Supplied for research use only.
- High purity (98.81%).
- Molecular formula C6H10O; molecular weight 98.14 g/mol.
- DMSO soluble (200 mg/mL); ultrasonic recommended.
- Appearance: colorless to light yellow; solid below ~28°C, liquid above ~33°C.
- Long-term storage stability: pure form -20°C for up to 3 years.
- COA and SDS available for quality and safety information.
Medchemexpress LLC Trans-Cinnamic acid | 140-10-3 | MFCD00004369 | 148.16 | 100 MG
trans-Cinnamic acid is a natural antimicrobial, with a minimal inhibitory concentration (MIC) of 250 μg/mL against the fish pathogen A. sobria, SY-AS1. This compound is used in various biological applications.
- Antimicrobial activity against various fish pathogens
- Shows moderate inhibition on rainbow trout intestinal isolates and gill isolate
- More effective on bacteria when the pH of the culture media is not neutralized
Medchemexpress LLC p-Coumaric acid-13C3 | 1261170-80-2 | 167.14 | 1 MG
p-Coumaric acid-13C3 is the 13C-labeled version of p-Coumaric acid. p-Coumaric acid is a prevalent isomer of cinnamic acid, known for its antitumor and anti-mutagenic properties. This compound is intended for research use only and is not sold to patients. Stable heavy isotopes, including carbon, are incorporated into drug molecules primarily as tracers for quantification during drug development. Deuteration, in particular, has gained attention for its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 2-Hydroxycinnamic acid | 614-60-8 | 98.71% | 164.16 | 25 MG
2-Hydroxycinnamic acid (Standard) is the analytical standard of 2-Hydroxycinnamic acid, intended for research and analytical applications. It is a phenolic acid with antimicrobial and antioxidant properties.
- Antimicrobial activity against Staphylococcus aureus, not susceptible to drug resistance.
- Shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 0.3 mM.
- Has neuroprotective and antitumor activity.
- The compound is an analytical standard, commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
Medchemexpress LLC 2-Hydroxycinnamic acid | 614-60-8 | 99.9% | 164.16 | 1 G
2-Hydroxycinnamic acid is a phenolic acid possessing antimicrobial and antioxidant properties. It exhibits antimicrobial activity against Staphylococcus aureus without succumbing to drug resistance. Furthermore, it demonstrates inhibitory effects on HIV/SARS-CoV S pseudovirus infection with an IC50 of 0.3 mM. The compound also presents neuroprotective and antitumor activities.
- Antimicrobial properties: Effective against Staphylococcus aureus, including drug-resistant strains.
- Antioxidant properties: Acts as an antioxidant.
- Antiviral activity: Inhibits infection of HIV/SARS-CoV S pseudovirus.
- Neuroprotective activity: Offers protective effects on neurons.
- Antitumor activity: Shows potential in combating tumors.