Cinnamic acids and derivatives
Medchemexpress LLC Ozagrel hydrochloride | 78712-43-3 | 99.9% | 100 MG
Ozagrel hydrochloride | 78712-43-3 | 99.9% | 100 MG
Cayman Chemical Ferulic Acid methyl ester, Purity: ≥98%, CAS: 2309-07-1, 500 mg
A lipophilic derivative of ferulic acid, demonstrating increased ability to cross cell membranes; at 10-25 µg/ml, inhibits the release of pro-inflammatory cytokines, blocks the expression of COX-2, and reduces NO generation from LPS-stimulated macrophages
Sigma Aldrich Fine Chemicals Biosciences trans-Ferulic acid >=99% | 537-98-4 | MFCD00004400 | 100G
trans-Ferulic acid >=99% | Purity: >=99% | Mol Wt: 194.18 | 537-98-4 | MFCD00004400 | 100G
Apexbio Technology LLC (E,E)-Bisdemethoxycurcumin 33171-05-0 10mg
(E E)-Bisdemethoxycurcumin (CAS 33171-05-0) is a naturally derived curcuminoid and a structural analog within the demethoxycurcumin class Research demonstrates that this compound modulates multiple inflammatory signaling pathways and alters the expression of various inflammatory mediators It has been shown to induce cell cycle arrest promote apoptosis in cancer cells and inhibit proliferation-related pathways (E E)-Bisdemethoxycurcumin is widely utilized in studies investigating the molecular mechanisms of inflammation tumor cell biology and the pharmacological properties of curcuminoid derivatives
Medchemexpress LLC Curcumin 5-8 | 890984-26-6 | 98.6% | 339.39 | 1 ML
Curcumin 5-8 (CUR5-8) is a potent and orally active naturally active curcumin (CUR) analog. It inhibits lipid droplet formation, increases autophagy, inhibits Apoptosis, and improves insulin resistance and insulin sensitivity.
- Potent and orally active curcumin analog
- Inhibits lipid droplet formation
- Increases autophagy
- Inhibits apoptosis
- Improves insulin resistance and insulin sensitivity
- Decreases palmitic acid (PA)-induced SREBP1 expression levels in AML12 cells
- Ameliorates insulin resistance and hepatic steatosis in mice with high-fat diet-induced obesity
Apexbio Technology LLC Tyrphostin 9 10537-47-0 25mg
Tyrphostin 9 is a selective inhibitor targeting platelet-derived growth factor receptor (PDGFR) and epidermal growth factor receptor (EGFR) It inhibits PDGFR autophosphorylation with an IC50 of approximately 2 5 M and EGFR kinase activity (IC50 around 460 M) Additionally Tyrphostin 9 inhibits platelet-derived growth factor (PDGF)-stimulated smooth muscle cell proliferation (IC50 approximately 40 nM) as well as phosphorylation of phospholipase C gamma (PLC IC50 2 5 M) and induction of PDGF-dependent c-fos expression In research models Tyrphostin 9 has been utilized to study receptor-mediated signal transduction and vascular injury-related neointimal proliferation processes
Medchemexpress LLC (4E)-7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one | 100667-52-5 | >98.0% | C19H20O2 | 10MG
(4E)-7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one (CAS 100667-52-5) is a diarylheptanoid research chemical used as a biochemical reagent for laboratory studies. It appears as a white to off-white solid and is characterized by molecular formula C19H20O2 and a molecular weight of 280.4 g/mol. The compound is provided in small research-scale quantities for analytical, assay, and synthetic applications.
- High purity (>98.0%).
- Accurate molecular formula C19H20O2.
- Suitable for assay and analytical use in research settings.
- Supplied in small milligram package sizes for laboratory workflows.
- Includes standard structural identifiers for cheminformatics (SMILES, InChIKey).
TARGETMOL CHEMICALS INC POLYINOSINIC-POLYCYTIDYL 25MG
Also available in 5 mg 10 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Polyinosinic-polycytidylic acid (Poly(IC)) is a synthetic double-stranded RNA (dsRNA) analog and is an immunostimulant that acts as the most potent interferon (IFN) inducer. It also is a Toll-like receptor- 3 (TLR3) agonist. purity: 98%
Apexbio Technology LLC Tyrphostin 9 10537-47-0 10mM (in 1mL DMSO)
Tyrphostin 9 is a selective inhibitor targeting platelet-derived growth factor receptor (PDGFR) and epidermal growth factor receptor (EGFR) It inhibits PDGFR autophosphorylation with an IC50 of approximately 2 5 M and EGFR kinase activity (IC50 around 460 M) Additionally Tyrphostin 9 inhibits platelet-derived growth factor (PDGF)-stimulated smooth muscle cell proliferation (IC50 approximately 40 nM) as well as phosphorylation of phospholipase C gamma (PLC IC50 2 5 M) and induction of PDGF-dependent c-fos expression In research models Tyrphostin 9 has been utilized to study receptor-mediated signal transduction and vascular injury-related neointimal proliferation processes
Medchemexpress LLC Entacapone | 130929-57-6 | MFCD00866580 | 100.0% | C14H15N3O5 | 10MG
Entacapone is a potent, reversible, peripherally acting catechol-O-methyltransferase (COMT) inhibitor provided as an analytical research standard for in vitro and biochemical studies, including Parkinson's disease and metabolic enzyme research. The material is supplied as a solid or solution and is intended for research use only.
- High purity for analytical and assay applications.
- Validated for COMT inhibition studies.
- Available in multiple small-scale pack sizes for laboratory use.
- Offered as both solid and premade solution formats.
- Useful as a reference standard in biochemical and enzymatic assays.
Medchemexpress LLC Tyrphostin AG 879 | 148741-30-4 | 99.3% | 316.46 | 1 ML
Tyrphostin AG 879 is a tyrosine kinase inhibitor that inhibits TrKA phosphorylation with an IC50 of 10 μM, but not TrKB and TrKC. It is also a selective ErbB2 tyrosine kinase inhibitor with an IC50 of 1 μM, demonstrating at least 500-fold higher selectivity to ErbB2 than EGFR. Tyrphostin AG 879 exhibits anticancer activity.
- Tyrosine kinase inhibitor.
- Inhibits TrKA phosphorylation (IC50 of 10 μM).
- Selective ErbB2 tyrosine kinase inhibitor (IC50 of 1 μM), with >500-fold selectivity over EGFR.
- Possesses anticancer activity.
- Significantly and dose-dependently decreases cell proliferation in various cell lines (e.g., HL-60, U-937, PC-3) in vitro.
- Induces a dose-dependent increase in apoptosis in several cell lines in vitro.
- Reduces tumor sizes in athymic, immunodepressed NOD/SCID female mice in vivo.
Apexbio Technology LLC Entacapone 130929-57-6 100mg
Entacapone (CAS 130929-57-6) is a selective second-generation inhibitor of catechol-O-methyltransferase (COMT) It demonstrates potent inhibition of total COMT in mouse liver with reported IC50 and Ki values of 20 1 nM and 10 7 nM respectively In rat models IC50 values for soluble COMT and membrane-bound COMT are 14 3 nM and 73 3 nM Entacapone is primarily utilized in research as an adjunct to levodopa and dopa decarboxylase inhibitor regimens in Parkinson s disease studies given its ability to suppress the formation of 3-O-methyldopa thereby enhancing levodopa bioavailability and prolonging its pharmacological effect
Med Vet International Fluoxetine, 20mg, 30 Tablets
VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED
Fluoxetine is a generic form of PROZac and is an SSRI antidepressant. It affects chemicals in the brain that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive disorder.