Cinnamic acids and derivatives
TARGETMOL CHEMICALS INC UMBRALISIB R-ENANTIOMER 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Umbralisib R-enantiomer (RP5264 R-enantiomer) is a delta inhibitor of PI3K and a less active enantiomer of TGR-1202. The IC50 of Umbralisib R-enantiomers against (delta)PI3 kinase is at least 20 times lower than that of the inhibitors against other PI3K isoforms (A (beta) and (gamma)). purity: 95%
TARGETMOL CHEMICALS INC TYRPHOSTIN AG1296 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 uM no activity to EGFR. purity: 99%
Apexbio Technology LLC Curcumin(Synonyms: Diferuloylmethane, Turmeric yellow, Natural yellow 3, CI 75300), 100mg, CAS: 458-37-7.
Curcumin (CAS 458-37-7) is a natural small molecule known to inhibit tyrosinase activity with an IC50 of 47 M It modulates multiple signaling pathways involved in tumorigenesis and inflammation influencing transcription factors growth factors cytokines receptors and enzymes Clinical trials at Phase I reported no observed toxicity at doses up to 12 g/day however oral bioavailability is limited ( 1% in Phase I/II studies) Additionally curcumin demonstrates potential for Alzheimer s research as evidenced by reducing beta-amyloid (A 40 A 42) production via downregulating presenilin-1 and GSK-3 in SH-SY5Y neuroblastoma cells
Proteochem Inc CHCA | 28166-41-8 | MFCD00004204 | 25 mg
CHCA | Mol Wt: 189.17 | 28166-41-8 | MFCD00004204 | 25 mg
Electron Microscopy Sciences Oil Red O, Certified C.I. DcRo-3 10 GR
Oil Red O is lysochrome (fat soluble dye) used demonstrate fat or lipids in fresh tissue sections. The polyazo group of dyes include the Oil Red, Sudan Red and the Sudan Blacks - all these dyes are interchangeable. Also known as Solvent Red 27, Sudan Red 5B.
Apexbio Technology LLC Tyrphostin AG 1296 146535-11-7 25mg
Tyrphostin AG 1296 (CAS 146535-11-7) is a selective inhibitor of platelet-derived growth factor receptor (PDGFR) kinase via ATP-competitive binding Its inhibitory activity (IC50 0 3 0 5 M) results from inducing conformational changes in the ATP-binding domain of PDGFR blocking receptor autophosphorylation induced by ligand binding In vitro studies demonstrate inhibition of PDGF-stimulated mitogenesis (IC50 1 5 M) and cell proliferation (IC50 3 2 M) using Swiss 3T3 cells without significant effects on EGF receptor signaling at concentrations up to 100 M Tyrphostin AG 1296 serves as a research tool for investigating PDGFR-mediated signaling pathways
Medchemexpress LLC 4-Hydroxybenzylidenemalononitrile | 3785-90-8 | MFCD00020189 | 98.0% | 170.17 g/mol | C10H6N2O | 25 MG
Tyrphostin 8 (4-hydroxybenzylidenemalononitrile, CAS 3785-90-8) is a small-molecule tyrosine kinase inhibitor reported to target EGFR, with additional activity against GTPases and the serine/threonine phosphatase calcineurin. Provided for research use in solid and DMSO solution formats, it has molecular formula C10H6N2O, molecular weight 170.17 g/mol, and listed purity 98.0%.
- Reported EGFR inhibitor (IC50 = 560 μM).
- Inhibits calcineurin phosphatase activity (IC50 = 21 μM).
- Also reported to inhibit GTPase activity.
- Supplied as solid and as 10 mM solution in DMSO for assay flexibility.
- Listed purity 98.0% suitable for biochemical research.
- Chemical formula C10H6N2O; molecular weight 170.17 g/mol.
TARGETMOL CHEMICALS INC TYRPHOSTIN AG 538 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Tyrphostin AG 538 is a chalcone compound an IGF-1 receptor kinase inhibitor (IC₅0 for 400 nM) that is potent cell-permeable reversible and competitive. purity: 99%
Medchemexpress LLC 4-(3-Fluorobenzyloxy)benzaldehyde | 66742-57-2 | 99.8% | C14H11FO2 | 25 G
4-(3-Fluorobenzyloxy)benzaldehyde is a drug intermediate for the synthesis of various active compounds. It has a molecular weight of 230.24 and appears as a solid.
- Serves as a building block for creating other active compounds.
- Suitable for research applications due to its high purity.
- Supplied in solid form.
- Intended for research purposes only.
Medchemexpress LLC Entacapone | 130929-57-6 | 99.2% | C14H15N3O5 | 25 MG
Entacapone | 130929-57-6 | 99.2% | C14H15N3O5 | 25 MG
Medchemexpress LLC Ferulic acid acyl-β-D-glucoside | 7196-71-6 | 1 ML
Ferulic acid acyl-β-D-glucoside is a metabolite of Ferulic Acid that can be isolated from flaxseed extract. It is identified as a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor and is intended for research use only.
- Metabolite of Ferulic Acid
- Can be isolated from flaxseed extract
- Inhibits fibroblast growth factor receptor 1 (FGFR1) and FGFR2
- Purity: 99.33%
- Appearance: White to off-white solid
- Soluble in water (50 mg/mL)
- Soluble in PBS (25 mg/mL)
- Initial source from plants (Rosaceae, Aruncus sylvester Kostel.)
Medchemexpress LLC 4-Acetoxycinnamic ac 100mg
4-Acetoxycinnamic acid is an acetate ester obtained by the formal condensation of the hydroxy group of trans-4-coumaric acid with acetic acid 4-Acetoxycinnamic acid is a member of cinnamic acids and a member of phenyl acetates 4-Acetoxycinnamic acid derives from a trans-4-coumaric acid[1]
eMolecules 332-04-7 | 4-(4-Fluorobenzyloxy)chlorobenzene | Oakwood Chemical | MFCD05105278 | 236.670 | C13H10ClFO | 98.000 | Fc1ccc(COc2ccc(Cl)cc2)cc1 | 1g | 537680719
4-(4-Fluorobenzyloxy)chlorobenzene | Oakwood Chemical | 332-04-7 | MFCD05105278 | 236.670 | C13H10ClFO | 98.000 | Fc1ccc(COc2ccc(Cl)cc2)cc1 | 1g | 537680719