Coumarins and derivatives
Medchemexpress LLC My-1076 | 3008262-76-5 | MFCD35444266 | 99.1% | 539.57 g·mol-1 | C29H33NO9 | 10 MG
MY-1076 is a small-molecule inhibitor of Yes-associated protein (YAP) used for laboratory research. It induces YAP degradation and apoptosis and shows potent antiproliferative activity against several cancer cell lines with low-nanomolar IC50s. Reported properties include CAS 3008262-76-5, formula C29H33NO9, molecular weight 539.57 g·mol-1, and high reported purity.
- Induces YAP degradation and apoptosis in vitro
- Potent antiproliferative activity with low-nanomolar IC50s
- High purity suitable for analytical and biological studies
- Available in multiple small-scale quantities for research use
- Intended for research use only; not for human or clinical use
Medchemexpress LLC 6-Hydroxycoumarin | 6093-68-1 | MFCD00630040 | 500 MG
6-Hydroxycoumarin is a coumarin that exhibits a range of biological activities. It is intended for research use only.
- Anti-inflammatory properties
- Anti-pyretic properties
- Anti-oxidant properties
- Vasodilator properties
- Anti-amoebic properties
- Anti-bacterial properties
- Anti-fungal properties
- Bacteriostatic properties
- Antitumor properties
Medchemexpress LLC 4-Hydroxycoumarin (standard) | 1076-38-6 | 50 MG
4-Hydroxycoumarin (Standard) is the analytical standard of 4-Hydroxycoumarin, intended for research and analytical applications. It is an orally active coumarin derivative and a versatile heterocyclic scaffold, frequently used in the synthesis of diverse organic compounds. The product exhibits both electrophilic and nucleophilic properties.
- Analytical standard.
- Intended for research and analytical applications.
- Orally active coumarin derivative.
- Versatile heterocyclic scaffold.
- Used in the synthesis of various organic compounds.
- Possesses both electrophilic and nucleophilic properties.
- Functions as an HIV protease inhibitor.
- Functions as a tyrosine kinase inhibitor.
- Displays anti-inflammatory effects.
- Displays antibacterial effects.
- Displays anti-tumor effects.
Medchemexpress LLC 4-Hydroxycoumarin | 1076-38-6 | 50 G
4-Hydroxycoumarin is an orally active coumarin derivative, a versatile heterocyclic scaffold used in synthesizing various organic compounds. It possesses both electrophilic and nucleophilic properties. It acts as an HIV protease inhibitor and tyrosine kinase inhibitor, and exhibits anti-inflammatory, antibacterial, and anti-tumor effects.
- Orally active coumarin derivative
- Versatile heterocyclic scaffold for organic compound synthesis
- Possesses both electrophilic and nucleophilic properties
- Acts as an HIV protease inhibitor
- Acts as a tyrosine kinase inhibitor
- Exhibits anti-inflammatory effects
- Exhibits antibacterial effects
- Exhibits anti-tumor effects
Medchemexpress LLC 2h-1-benzopyran-2-one, 7-ethoxy-4-methyl- | 87-05-8 | MFCD00016971 | 99.4% | 25 G
7-Ethoxy-4-methylcoumarin is a coumarin derivative that serves as a substrate probe for mammalian cytochromes P450 1A1, 2B4, and 2B6. It is intended for research use only and not for sale to patients.
- Coumarin derivative.
- Functions as a substrate probe for specific cytochrome P450 enzymes.
- Useful in research and analytical applications.
- Targets CYP1A1, CYP2B4, and CYP2B6.
- Can be classified as a fluorescent dye.
- Used in labeling chemistry.
- A metabolic enzyme/protease.
Medchemexpress LLC 7-Ethoxy-4-methylcoumarin | 87-05-8 | 99.44% | 50 G
7-Ethoxy-4-methylcoumarin is a coumarin derivative that functions as a substrate probe for mammalian cytochromes P450 1A1, 2B4, and 2B6.
- Coumarin derivative
- Substrate probe of mammalian cytochromes P450 1A1, 2B4 and 2B6
- Molecular weight: 204.22
- Formula: C12H12O3
- Appearance: Solid
- Color: White to off-white
- SMILES: O=C1C=C(C)C2=CC=C(OCC)C=C2O1
Medchemexpress LLC 7-Ethoxy-4-methylcoumarin | 87-05-8 | 99.44% | 100 G
7-Ethoxy-4-methylcoumarin is a coumarin derivative that functions as a substrate probe for mammalian cytochromes P450 1A1, 2B4, and 2B6.
- Coumarin derivative
- Substrate probe
- Targets mammalian cytochromes P450 1A1, 2B4, and 2B6
Indofine Chemical Linarin With Hplc, 5 Mg
LINARIN with HPLC, Flavonoid & Coumarins, 480-36-4, 98.5% by HPLC, 5 mg
Medchemexpress LLC AZP-531 | 1088543-62-7 | 99.8% | 962.02 | 5 MG
AZP-531 | 1088543-62-7 | 99.8% | 962.02 | 5 MG
Selleck Chemical LLC Esculetin S4711-100mg
Esculetin (Cichorigenin Aesculetin) is a coumarin derivative found in various natural plant products with various biological and pharmaceutical properties including anti-edema anti-inflammatory and anti-tumour effects It inhibits lipoxygenases (LOs)
Selleck Chemical LLC 4-Methylesculetin S4966-25mg
4-methylesculetin is one of the coumarin derivatives with great anti-oxidant and anti-inflammatory activities 4-Methylesculetin inhibits myeloperoxidase (MPO) activity and reduces IL-6 level
Apexbio Technology LLC Palomid 529 914913-88-5 5mg
Palomid 529 (CAS 914913-88-5) is a small-molecule inhibitor of the PI3K/Akt/mTOR signaling pathway targeting both TORC1 and TORC2 complexes It exhibits potent anti-proliferative activity in the NCI-60 cell line panel with GI50 values below 35 M In endothelial cell assays Palomid 529 inhibits VEGF- and bFGF-induced proliferation with IC50 values of 20 nM and 30 nM respectively The PI3K/Akt/mTOR pathway is implicated in tumor cell survival proliferation angiogenesis and resistance to apoptosis Palomid 529 has also demonstrated the ability to suppress radiation-induced expression of Id-1 VEGF MMP-2 and MMP-9 expanding its utility in studies of cancer biology and radiotherapy sensitization
TARGETMOL CHEMICALS INC HX 531 10MG
Also available in 1 mg 5 mg 25 mg 50 mg and bulk. Please contact Fisher for quotes. HX 531 is a potent antagonist of the retinoid X receptor with an IC50 value of 18 nM. purity: 99%
Apexbio Technology LLC 6,7-Dihydroxycoumarin 305-01-1 10mM (in 1mL DMSO)
6 7-Dihydroxycoumarin (CAS 305-01-1) also known as esculetin is a naturally occurring coumarin derivative extracted from Aesculus hippocastanum Linn This compound exhibits notable antioxidant activity primarily by scavenging reactive oxygen species and inhibiting lipid peroxidation Additionally 6 7-dihydroxycoumarin has been studied for its modulatory effects on various cellular signaling pathways implicated in inflammation and apoptosis Its applications in biomedical research include investigations into oxidative stress inflammation and related disease models The compound is soluble in ethanol and dilute alkali and should be stored in a sealed cool and dry environment to preserve stability