Flavonoids
Medchemexpress LLC Acacetin (5,7-dihydroxy-4'-methoxyflavone) | 480-44-4 | MFCD00016936 | 99.7% | 284.26 | C16H12O5 | 10 MG
Acacetin (5,7-dihydroxy-4'-methoxyflavone) is an O-methylated flavone used as a research reagent for studies of apoptosis, autophagy, and inflammatory signaling. It is supplied as a high-purity reference material for in vitro and preclinical experiments.
- CAS number: 480-44-4.
- Molecular formula: C16H12O5.
- Molecular weight: 284.26 g/mol.
- Purity: 99.7%.
- Available pack sizes: 1 mg-1 g for laboratory use.
- Documentation provided: data sheet, certificate of analysis, and safety data sheet.
Medchemexpress LLC Hesperidin | 520-26-3 | MFCD00075663 | 96.5% | 610.56 g/mol | C28H34O15 | 10 MG
Hesperidin (analytical standard) is a flavanone glycoside isolated from citrus fruits and supplied as a solid reference material for research and analytical applications. It is intended for method development, calibration, and quality control in chromatographic and mass spectrometric assays, and is characterized to support reliable identification and quantitation in analytical workflows.
- Intended for analytical and research use.
- Solid reference material for HPLC and LC-MS workflows.
- Reported purity 96.54%, supporting accurate quantitation.
- Includes standard chemical identifiers (CAS 520-26-3) for traceability.
- Available in small package sizes suitable for analytical laboratories.
eMolecules 14756-24-2 | Medchem Express | DiMNF | 5mg | 724441992 | HY-103222 | MFCD00143008 | 332.355 | C21H16O4
Medchem Express | Oxibendazole | 50mg | 446272455 | HY-B0299 | 20559-55-1 | MFCD00847838 | 249.270 | C12H15N3O3
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Medchemexpress LLC Acacetin | 480-44-4 | 284.26 | 50 MG
Acacetin is an orally active flavonoid, 5,7-Dihydroxy-4'-methoxyflavone, isolated from Dendranthema morifolium. It acts as a PI3Kγ inhibitor, inducing cell cycle arrest, apoptosis, and autophagy in various cancer cells. This compound exhibits potent anti-cancer and anti-inflammatory activities, making it a promising candidate for pain-related disease research.
- Orally active flavonoid
- Derived from Dendranthema morifolium
- Docks in ATP binding pocket of PI3Kγ
- Causes cell cycle arrest in cancer cells
- Induces apoptosis and autophagy in cancer cells
- Potent anti-cancer activity
- Potent anti-inflammatory activity
- Potential for pain-related diseases research
- Suppresses microglial activation in neuroinflammation models
- Reduces neuronal cell death in ischemia models
- Decreases visceral and inflammatory nociception
Medchemexpress LLC 5,7-Dimethoxyflavone | 21392-57-4 | 50 MG
5,7-Dimethoxyflavone is an analytical standard and a major component of Kaempferia parviflora. It exhibits anti-obesity, anti-inflammatory, and antineoplastic effects. This product is intended for research and analytical applications.
- Inhibits cytochrome P450 (CYP) 3As
- Potent breast cancer resistance protein (BCRP) inhibitor
- Used for qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Shipping is at room temperature in continental US; may vary elsewhere. Store under recommended conditions in the Certificate of Analysis.
Sigma Aldrich Fine Chemicals Biosciences 3',4'-Dimethoxyflavone | 4143-62-8 | MFCD00143009 | 5MG
3',4'-Dimethoxyflavone | Purity: >=98% (HPLC) | Mol Wt: 282.29 | 4143-62-8 | MFCD00143009 | 5MG
Medchemexpress LLC 5-methoxyflavone | 42079-78-7 | MFCD00016942 | 100.0% | 252.26 g·mol⁻¹ | C16H12O3 | 1 ML
5-Methoxyflavone is a flavonoid-class small molecule (C16H12O3, MW 252.26 g·mol⁻¹) reported as a DNA polymerase-beta inhibitor and a neuroprotective agent. It is supplied as both a solid and a ready-to-use 10 mM solution in DMSO for in vitro research, with storage and solvent recommendations to support reproducible experiments.
- High purity (99.97%) suitable for biochemical assays.
- Available as a 10 mM solution in DMSO for ready-to-use applications.
- Also supplied as solid in multiple pack sizes (25 mg-500 mg).
- Molecular formula C16H12O3; molecular weight 252.26 g·mol⁻¹.
- Recommended solvent: DMSO; may require sonication to dissolve.
- Storage recommendations: powder -20°C for long term, solution -80°C for extended storage.
Medchemexpress LLC 6-Methoxyflavanone | 3034-04-6 | 254.28 | 1 G
6-Methoxyflavanone (6-MeOF) is a flavonoid compound capable of crossing the blood-brain barrier. It acts as a positive allosteric modulator of GABAA receptors, specifically showing regulatory effects on human recombinant α1β2γ2L and α2β2γ2L GABAA receptors, with low activity on the α1β2 GABAA receptor. Additionally, it inhibits the activation of bitter receptors hTAS2R39 and hTAS2R14, exhibiting a reversible and non-overcome antagonistic effect. This compound is noted for its anti-anxiety, analgesic, and neuropathic pain relief properties.
- Flavonoid compound
- Crosses the blood-brain barrier
- Positive allosteric modulator of GABAA receptors
- Inhibits bitter receptors hTAS2R39 and hTAS2R14
- Exhibits anti-anxiety effects
- Provides analgesia
- Offers relief of neuropathic pain
TARGETMOL CHEMICALS INC 5 7 8-Trimethoxyflavone 10MG
Also available in 1 mg, 5 mg, 25 mg and bulk. Please contact Fisher for quotes. 5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether) is a compound extracted from *Andrographis paniculata*, exhibiting anti-inflammatory activity and NO inhibition. Purity 99.89%
Medchemexpress LLC 4'-Hydroxyflavanone | 6515-37-3 | 100 MG
4'-Hydroxyflavanone is an inhibitor of SREBP maturation and lipid synthesis. It is a synthetic analogue of flavanone and has potential for research into hepatic steatosis and dyslipidemia.
- Inhibitor of SREBP maturation
- Inhibitor of lipid synthesis
- Synthetic analogue of flavanone
- Potential for hepatic steatosis research
- Potential for dyslipidemia research
- Molecular weight: 240.25
- Formula: C15H12O3
- Appearance: white to light yellow solid
- Purity: 99.75%
- Soluble in DMSO (100 mg/mL)
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month