Flavonoids
Medchemexpress LLC HY-N0436 5mg Medchemexpress, Engeletin CAS:572-31-6 Purity:>98%
Medchemexpress, HY-N0436 5mg Engeletin CAS:572-31-6 Engeletin is a flavanonol glycoside isolated from hymenaea martiana, inhibits NF-κB signaling-pathway activation, and possesses anti-inflammatory, analgesic, diuresis, detumescence, and antibiosis effects. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC Naringin S2329-500mg
Naringin (Naringoside) is a flavanone glycoside which exerts a variety of pharmacological effects such as antioxidant activity blood lipid lowering anticancer activity and inhibition of cytochrome P450 enzymes
Sigma Aldrich Fine Chemicals Biosciences Naringin >=95% (HPLC) | 10236-47-2 | MFCD00148888 | 100G
Naringin >=95% (HPLC) | Purity: >=95% (HPLC) | Mol Wt: 580.53 | 10236-47-2 | MFCD00148888 | 100G
Apexbio Technology LLC FLAVANONE-100MG
Flavanone (CAS No 487-26-3) is a key compound in the study of polyphenols primarily derived from citrus fruits and certain other plants It functions through various biological pathways notably by modulating antioxidant mechanisms influencing enzyme activity and interacting with cellular signaling pathways such as those involving kinases and transcription factors In vitro studies frequently demonstrate its activity in the nanomolar to low micromolar range showcasing its potential in modulating inflammatory responses and oxidative stress Flavanone is widely utilized in cell models to investigate these effects and is also employed in animal studies to explore its pharmacological potential including its efficacy in drug screening applications Experimental concentrations typically depend on the specific research design
TARGETMOL CHEMICALS INC PINOCEMBRIN 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Pinocembrin (57-Dihydroxyflavanone) is a flavanone a type of flavonoid. It is an antioxidant found in damiana honey fingerroot and propolis. purity: 98%
TARGETMOL CHEMICALS INC PHILLYRIN 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Phillyrin (Forsythin) is a novel AMPK activator has anti-obesity effects in nutritive obesity mice it can prevent lipid accumulation in HepG2 cells by blocking the expression of SREBP-1c and FAS through LKB1/AMPK activation. Phillyrin(Forsythin) may be a new preventive agent of acute lung injury in the clinical setting it potentially contributes to the suppression of the activation of MAPK and NF-(kappa)B pathways it also has protective effects on H2O2-induced oxidative stress and apoptosis in PC12 cells. purity: 99%
![Medchemexpress LLC 5-hydroxy-3-[(2-hydroxyphenyl)methyl]-7-(2-methylnonan-2-yl)chromen-2-one | 1399049-81-0 | 98.0% | 408.53 | C26H32O4 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000238635.png-250.jpg)
Medchemexpress LLC 5-hydroxy-3-[(2-hydroxyphenyl)methyl]-7-(2-methylnonan-2-yl)chromen-2-one | 1399049-81-0 | 98.0% | 408.53 | C26H32O4 | 10MG
PSB-SB-487 is a coumarin-derived research compound that acts as a potent GPR55 antagonist and CB2 receptor agonist, used in preclinical studies of metabolic disorders, neurodegeneration, neuropathic pain, and cancer. It is supplied for laboratory research in multiple small-mass quantities and includes chemical identifiers and structural data for experimental reproducibility.
- Potent GPR55 antagonist and CB2 agonist.
- Molecular formula C26H32O4 and molecular weight 408.53.
- High purity (98.0%) suitable for research applications.
- Available in small-mass sizes for laboratory experiments.
- Relevant for studies of metabolic disorders, neurodegeneration, pain, and cancer.
- Provided with CAS number and structural identifiers for traceability.
Selleck Chemical LLC AMG 487
AMG 487 is an orally active and selective CXC chemokine receptor 3 (CXCR3) antagonist that inhibits the binding of IP-10 (CXCL10) and ITAC (CXCL11) to CXCR3 with IC50 of 8 0 nM and 8 2 nM respectively
Indofine Chemical GENISTEIN, Flavonoid & Coumarins, 446-72-0, 98+%, 100 mg
GENISTEIN, Flavonoid & Coumarins, 446-72-0, 98+%, 100 mg
Apexbio Technology LLC (-)-epicatechin 490-46-0 5mg
(-)-Epicatechin (CAS 490-46-0) is a flavonoid compound known for inducing pancreatic -cell regeneration and modulating nitric oxide (NO) metabolism It inhibits nitric oxide-related nitrite formation induced by interferon- and lipopolysaccharide in mouse macrophages and reduces peroxynitrite-mediated tyrosine nitration in HL-60 human leukemia cells Additionally in human endothelial cells (HUVECs) it enhances NO production displaying vasodilatory properties In diabetic rat models (alloxan-induced) (-)-epicatechin administration promotes -cell recovery reduces hyperglycemia and prevents -cell necrosis This profile underscores its research relevance for diabetes and vascular biology investigations
Medchemexpress LLC Apigenin-7-glucuronide | 29741-09-1 | 446.36 | 1 ML
Apigenin-7-glucuronide is a chemical compound that acts as an inhibitor of Matrix Metalloproteinases (MMP) activities, with specific IC50 values for MMP-3, MMP-8, MMP-9, and MMP-13. This product is intended for research use only.
- Inhibits Matrix Metalloproteinases (MMP) activities
- Purity of 99.74%
- Available as a solid
- Soluble in DMSO for in vitro studies
- Specific storage conditions for powder and in solvent
Medchemexpress LLC Luteolin 7-O-glucuronide | 29741-10-4 | 462.36 | 25 MG
Luteolin 7-O-glucuronide is an inhibitor of Matrix Metalloproteinases (MMP) activities. It is a solid, white to light yellow in color, and is intended for research use only. This compound inhibits NO production and mRNA expression of various inflammatory mediators in LPS-stimulated RAW 264.7 macrophages.
- Inhibits matrix metalloproteinases (MMP) activities
- Inhibits NO production and mRNA expression of inflammatory mediators
- Improves depression-like and stress coping behaviors in mouse models
- Available as a white to light yellow solid
- For research use only
Cayman Chemical EpIcatechIn 10mg
A polyphenol flavonoid with diverse biological activities; scavenges DPPH radicals in a cell-free assay at 5 µM; inhibits COX-1 (IC50 = 3.2 μM); acts synergistically with epigallocatechin gallate to induce apoptosis in, and reduce the proliferation of, PC-9 cells at 200 µM; reduces LPS-induced increases in plasma creatinine and urea levels in a rat model of renal inflammation at 80 mg/kg
Apexbio Technology LLC (-)-epicatechin 490-46-0 10mM (in 1mL DMSO)
(-)-Epicatechin (CAS 490-46-0) is a flavonoid compound known for inducing pancreatic -cell regeneration and modulating nitric oxide (NO) metabolism It inhibits nitric oxide-related nitrite formation induced by interferon- and lipopolysaccharide in mouse macrophages and reduces peroxynitrite-mediated tyrosine nitration in HL-60 human leukemia cells Additionally in human endothelial cells (HUVECs) it enhances NO production displaying vasodilatory properties In diabetic rat models (alloxan-induced) (-)-epicatechin administration promotes -cell recovery reduces hyperglycemia and prevents -cell necrosis This profile underscores its research relevance for diabetes and vascular biology investigations