Flavonoids
Medchemexpress LLC Myricetin 3'-glucoside | 520-14-9 | 1 MG
Myricetin 3'-glucoside is a glycoside derivative of quercetin. It significantly prevents ethanol-induced hepatotoxicity by reducing hepatic transaminase activity and inflammatory response in HepG2 cells, demonstrating a protective effect on alcohol-induced liver injury.
- Glycoside derivative of quercetin
- Prevents ethanol-induced hepatotoxicity
- Reduces hepatic transaminase activity
- Reduces inflammatory response in HepG2 cells
- Protective effect on alcohol-induced liver injury
Indofine Chemical Naringenin, 98.2%, 5 Gm
Moelcular Formula: C15H12O5, Purity: 98%, Molecular Weight: 272.26, Appearance: Brown crystalline powder, Solubility: Soluble in alcohol, ether, benzene, Storage conditions: Store in a cool, dry place, Also known as 5,7,4'-Trihydroxyflavanone; 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Medchemexpress LLC 7-Hydroxyflavone | 6665-86-7 | 100 MG
7-Hydroxyflavone is a flavonoid isolated from *Clerodendrum phlomidis*, demonstrating anti-inflammatory activity. It protects renal cells from nicotine (NIC)-associated cytotoxicity through the ERK/Nrf2/HO-1 pathway, and inhibits PKM2, COX-2, and 5-LOX. This compound is orally active.
- Isolated from *Clerodendrum phlomidis*
- Protects renal cells from nicotine-associated cytotoxicity
- Inhibits PKM2 with an IC50 of 2.12 μM
- Inhibits COX-2 and 5-LOX with IC50s of 27 μg/mL and 33 μg/mL
- Orally active
- Ameliorates neuropathic pain in mice models
- Improves high-fat diet-induced non-alcoholic fatty liver disease
- Reduces malondialdehyde (MDA) and ROS levels in HepG2 cells
Medchemexpress LLC 7-Hydroxyflavone | 6665-86-7 | MFCD00006835 | 50 MG
7-Hydroxyflavone is a flavonoid isolated from *Clerodendrum phlomidis* that exhibits anti-inflammatory activity. It protects renal cells from nicotine-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway. This orally active compound also inhibits PKM2, COX-2, and 5-LOX, and has demonstrated antioxidant activity and efficacy in various animal models.
- Isolated from *Clerodendrum phlomidis*
- Exhibits anti-inflammatory activity
- Protects renal cells from nicotine-associated cytotoxicity
- Inhibits PKM2, COX-2, and 5-LOX
- Orally active
- Reduces malondialdehyde (MDA) and reactive oxygen species (ROS) levels
- Increases superoxide dismutase (SOD) and glutathione (GSH) levels
- Ameliorates ischemia/reperfusion injury
- Improves high-fat diet-induced non-alcoholic fatty liver disease and obesity
- Purity of 99.89%
- Appearance is a white to off-white solid
Medchemexpress LLC Myricetin 3'-glucoside | 520-14-9 | 5 MG
Myricetin 3'-glucoside is a glycoside derivative of quercetin. It significantly prevents ethanol-induced hepatotoxicity by reducing hepatic transaminase activity and inflammatory response in HepG2 cells, indicating a protective effect on alcohol-induced liver injury. It has a molecular weight of 480.38 and a chemical formula of C21H20O13.
- Purity: 99.98%
- Appearance: solid, off-white to light yellow
- Molecular weight: 480.38
- Formula: C21H20O13
- Smiles: O=C1C(C(OC(C(C=C2O)=CC(O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]([C@H]3O)CO)=C2O)=C1O)=CC(O)=C4)=C4O
- Structure classification: flavonoids, flavonols
- Initial source: plants, Myrtaceae, Syzygium malaccense (L.) Merr. et Perry
- Solubility (in vitro): DMSO: 50 mg/mL (104.08 mM; needs ultrasonic; hygroscopic DMSO has a significant impact on solubility, use newly opened DMSO)