Isoflavonoids
Cayman Chemical SophorIcosIde 250mg
An isoflavone glycoside with diverse biological activities; inhibits oleic acid-induced lipid accumulation in HepG2 cells and stimulates glucose uptake in C2C12 mouse skeletal muscle myoblasts at 10 µM; inhibits compound 48/80- or histamine-induced scratching behavior in mice at 2 mg/kg; reduces serum levels of IgE in a mouse model of atopic dermatitis; increases serum levels of osteocalcin and ALP and restores mechanical bone hardness in an ovariectomized rat model of osteoporosis; decreases hepatic cholesterol and triglyceride levels, serum LDL and apolipoprotein B levels, and hepatic injury in a mouse model of fructose-induced liver injury at 80 and 160 mg/kg
eMolecules 552-66-9 | Daidzin | Chem-Impex | MFCD01871344 | 416.382 | C21H20O9 | 98.000 | OCC1OC(Oc2ccc3c(c2)occ(-c2ccc(O)cc2)c3=O)C(O)C(O)C1O | 1g | 490842898
Daidzin | Chem-Impex | 552-66-9 | MFCD01871344 | 416.382 | C21H20O9 | 98.000 | OCC1OC(Oc2ccc3c(c2)occ(-c2ccc(O)cc2)c3=O)C(O)C(O)C1O | 1g | 490842898
![Research Products International Corp Genistein [4',5,7-Trihydroxyisoflavone], 25 Milligrams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-G36000-0.025.JPG-250.jpg)
Research Products International Corp Genistein [4',5,7-Trihydroxyisoflavone], 25 Milligrams
Inhibits protein tyrosine kinases.
Apexbio Technology LLC Genistein(Synonyms: 4',5,7-Trihydroxyisoflavone, Genisteol, Prunetol, Sophoricol, Differenol A), 100mg, CAS: 446-72-0.
Genistein (CAS 446-72-0) is an isoflavonoid compound that selectively inhibits protein tyrosine kinases enzymes implicated in signaling pathways associated with oncogenic activity and cellular proliferation Genistein inhibits tyrosine kinase activity with an IC50 of approximately 8 M In NIH-3T3 cell assays genistein suppresses epidermal growth factor (EGF)-mediated mitogenesis (IC50 12 M) and insulin-mediated effects (IC50 19 M) additionally inhibiting EGF-induced activation of S6 kinase at a concentration of 6 15 M In animal models oral administration of genistein demonstrates dose-dependent inhibition of prostate adenocarcinoma development highlighting its utility in cancer biology research and potential chemopreventive applications
Medchemexpress LLC Genistein 7-β-D-Glucuronide | 38482-81-4 | 98.8% | 446.36 | 1 MG
Genistein 7-β-D-Glucuronide is a natural product that functions as an inhibitor of tubulogenesis and endothelial migration. It is intended for research use only.
- Inhibits tubulogenesis
- Inhibits endothelial migration
- Natural product
- Targets vascular endothelial growth factor receptor (VEGFR)
- Relevant to metabolic or endocrine disease research
Selleck Chemical LLC Daidzein S1849-50mg
Daidzein is a natural isoflavone phytoestrogen found in Leguminosae used as a component of foods and dietary supplements Daidzein is a soy isoflavone which acts as a PPAR activator
Medchemexpress LLC PHGDH-inactive | 1914971-16-6 | 99.9% | 1 ML
PHGDH-inactive is a chemically defined negative control compound used to validate PHGDH inhibitor assays. It is supplied in both ready-to-use solution and solid formats for in vitro research use only.
- Used as a negative control in PHGDH inhibitor assays.
- Available as a 10 mM solution in DMSO and as solid powders.
- High chemical purity (about 99.9%).
- Soluble in DMSO at approximately 83.33 mg/mL; ultrasonic assistance may be required.
- Store at 4°C protected from light; in solution, store long-term at -80°C.
- For research use only; not for human or clinical use.