Linear 1 3-diarylpropanoids
Medchemexpress LLC 1,3-Propanedione, 1,3-diphenyl- | 120-46-7 | 98.0% | 224.26 | 1 ML
Dibenzoylmethane is a minor ingredient in licorice that activates Nrf2, playing a role in preventing various cancers and oxidative damage. It acts as an analog of curcumin, causing dissociation from Keap1 and nuclear translocation of Nrf2. It is provided for research use only.
- Activates Nrf2 pathway
- Analog of curcumin
- Prevents cancers and oxidative damage
- Increases HO-1 and Nrf2 protein expression
- Protects against CCl4-induced liver damage in wild-type mice
Apexbio Technology LLC Avobenzone 70356-09-1 10mM (in 1mL DMSO)
Avobenzone (70356-09-1) is a small-molecule agonist targeting estrogen receptor (ER ) It is designed to bind directly to ER thereby modulating endocrine signaling pathways Avobenzone exerts its biological activity primarily through direct receptor binding and estrogenic agonist activity Based on these properties Avobenzone holds research potential in studies investigating endocrine-disrupting chemicals mechanisms of photoprotection UV-induced cellular damage and skin pathology
Medchemexpress LLC Xanthohumol | 6754-58-1 | 354.40 | 1 ML
Xanthohumol is a principal flavonoid derived from hops, acting as an inhibitor of diacylglycerol acyltransferase (DGAT), COX-1, and COX-2. It exhibits anti-cancer and anti-angiogenic properties. Additionally, Xanthohumol demonstrates antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2, and cytomegalovirus (CMV).
- Inhibits diacylglycerol acyltransferase (DGAT), COX-1, and COX-2.
- Shows anti-cancer activities.
- Shows anti-angiogenic activities.
- Has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2, and cytomegalovirus (CMV).
Medchemexpress LLC Xanthohumol | 6754-58-1 | MFCD00210576 | 354.40 | 500 MG
Xanthohumol is one of the principal flavonoids isolated from hops, known for its inhibitory effects on diacylglycerol acetyltransferase (DGAT), COX-1, and COX-2. It demonstrates anti-cancer, anti-angiogenic, and antiviral activities against various viruses including bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2, and cytomegalovirus (CMV). This product is intended for research use only.
- Inhibitor of DGAT, COX-1, and COX-2
- Exhibits anti-cancer activity
- Possesses anti-angiogenic activity
- Shows antiviral activity against BVDV, rhinovirus, HSV-1, HSV-2, and CMV
- Appears as a yellow to orange solid
Medchemexpress LLC Xanthohumol | 6754-58-1 | MFCD00210576 | 99.3% | 354.40 g/mol | C21H22O5 | 10 MG
Xanthohumol (Standard) is an analytical reference standard of xanthohumol, a prenylated chalconoid flavonoid isolated from hops, supplied for research and analytical use in qualitative and quantitative assays and method development for HPLC, GC, and MS.
- Purity 99.30%.
- Molecular formula C21H22O5.
- Molecular weight 354.40 g/mol.
- Supplied as a solid, typically 10 mg.
- Intended for use as an analytical standard for HPLC, GC, and MS assays.
- Certificate of analysis provided; follow storage conditions in the CoA.
Medchemexpress LLC Xanthohumol (Standard) | 6754-58-1 | 354.40 | 25 MG
Xanthohumol (Standard) | 6754-58-1 | 354.40 | 25 MG
Medchemexpress LLC Xanthohumol C | 189299-05-6 | 99.2% | 352.38 | C21H20O5 | 10 MG
Xanthohumol C is a prenylchalcone natural product isolated from the hops plant Humulus lupulus. It is used in research and has reported cytotoxic and antiproliferative activity in human cancer cell lines.
- Chemical formula C21H20O5.
- Molecular weight 352.38.
- Purity 99.2%.
- Reported cytotoxicity against HeLa cells (IC50 12.5 μM).
- Antiproliferative activity against MCF7 cells (IC50 15.7 μM for 2 days, 6.87 μM for 4 days).
- Supplied as a 10 MG research quantity.
Medchemexpress LLC Xanthohumol C | 189299-05-6 | 352.38 | 5 MG
Xanthohumol C is a prenylchalcone that can be isolated from the hops of Humulus lupulus. It is categorized as a natural compound with a molecular weight of 352.38 and a chemical formula of C21H20O5. This compound appears as a light yellow to yellow solid and is intended for research use only, not for sale to patients.
- It is a prenylchalcone, a type of natural compound.
- It can be isolated from the hops of Humulus lupulus.
- It exhibits cytotoxicity against human HeLa cells with an IC50 of 12.5 μM.
- It shows antiproliferative activity against human MCF7 cells with IC50 values of 15.7 μM (2 days) and 6.87 μM (4 days).
Medchemexpress LLC Xanthohumol D | 274675-25-1 | 370.40 | 5 MG
Xanthohumol D, isolated from hops, is an inhibitor of quinone reductase-2 (QR-2) with an IC50 value of 110 μM, and binds to the active site of QR-2. It shows antiproliferative activity on human cancer cell lines in vitro.
- Inhibitor of quinone reductase-2 (QR-2) with an IC50 value of 110 μM
- Binds to the active site of QR-2
- Exhibits antiproliferative activity on human cancer cell lines in vitro