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Alkali metal salts are naturally-occurring compounds available in a wide variety of chemical compositions, quantities, purities, and reagent grades. They have numerous chemical, biological, pharmaceutical, educational, research, and everyday applications.
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Cesium chloride (CAS 7647-17-8) is a small molecule known for its ability to block potassium channels specifically suppressing the pacemaker current (I sub f /sub ) and the hyperpolarization-activated cationic current (I sub h /sub ) In neuronal models it has been shown to inhibit activation of caspase-3 and prevent apoptosis in cerebellar granule neurons subjected to serum and potassium deprivation a process associated with inactivation of GSK-3 Cesium chloride is widely employed in neurophysiological studies to investigate ion channel function and the molecular mechanisms underlying neuronal survival
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Cesium chloride (CAS 7647-17-8) is a small molecule known for its ability to block potassium channels specifically suppressing the pacemaker current (I sub f /sub ) and the hyperpolarization-activated cationic current (I sub h /sub ) In neuronal models it has been shown to inhibit activation of caspase-3 and prevent apoptosis in cerebellar granule neurons subjected to serum and potassium deprivation a process associated with inactivation of GSK-3 Cesium chloride is widely employed in neurophysiological studies to investigate ion channel function and the molecular mechanisms underlying neuronal survival
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Dextran sulfate sodium salt (DSS CAS 9011-18-1) is a water-soluble polyanionic derivative obtained by esterifying dextran with chlorosulfonic acid resulting in approximately 17% sulfur content equivalent to roughly 2 3 sulfate groups per glucose unit DSS induces epithelial damage and intestinal inflammation closely resembling human inflammatory bowel diseases (IBD) including ulcerative colitis Varying its dosage and regimen generates acute chronic or relapsing colitis models for biomedical disease research DSS is also widely utilized in molecular biology procedures such as lipoprotein precipitation enhancing nucleic acid probe hybridization and ribosome isolation
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