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Reactive nonmetal salts are ionic compounds formed with elements classified as reactive nonmetals. These salts are available in a variety of chemical compositions and quantities, and most are formed from the five gaseous reactive nonmetals.
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Bigelovin is a sesquiterpene lactone (CAS 3668-14-2; C17H20O5; MW 304.34) that acts as a selective retinoid X receptor α (RXRα) agonist. It suppresses tumor growth by inducing apoptosis and autophagy via inhibition of the mTOR pathway and modulation of reactive oxygen species (ROS). Supplied for research use with documented solubility and storage guidance.
Selective retinoid X receptor α (RXRα) agonist activity.
Induces apoptosis and autophagy in cancer model studies.
Available in small research quantities suitable for in vitro and in vivo formulation.
Includes detailed solubility and stock preparation guidance.
Storage guidance provided: protect from light at 4°C; solvent storage conditions included.
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2'-OTBS MeC(Bz) amidite is a Amidite reagent (Subcategory: 2'-OH Series) sold by WuXi TIDES. Offered in 10 g. Store at -20 °C. SDS available for reference.
Specifications - CAS: 160107-14-2 - MDL: No data - InChIKey: CSRPNZIUSKVNCV-YIZRFDMBSA-N - Molecular Weight: 978.211761998 - Molecular Formula: C53H68N5O9PSi - Purity: ≥95% - Container Type: 60 mL HDPE - Pack Size: 10 g - Net Weight: 10 g - Gross Weight: 25 g - Commodity Code: 29349990 - Country Of Origin: China - IUPAC: (2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite - SMILES: CC(N(P(O[C@H]1[C@H]([C@H](N2C(N=C(C(C)=C2)NC(C3=CC=CC=C3)=O)=O)O[C@@H]1COC(C4=CC=C(C=C4)OC)(C5=CC=C(C=C5)OC)C6=CC=CC=C6)O[Si](C)(C(C)(C)C)C)OCCC#N)C(C)C)C
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2'-OTBS MeC(Bz) amidite is a Amidite reagent (Subcategory: 2'-OH Series) sold by WuXi TIDES. Offered in 10 g. Store at -20 °C. SDS available for reference.
Specifications - CAS: 160107-14-2 - MDL: No data - InChIKey: CSRPNZIUSKVNCV-YIZRFDMBSA-N - Molecular Weight: 978.211761998 - Molecular Formula: C53H68N5O9PSi - Purity: ≥95% - Container Type: 250 mL Glass (28-400) - Pack Size: 10 g - Net Weight: 10 g - Gross Weight: 179.7 g - Commodity Code: 29349990 - Country Of Origin: China - IUPAC: (2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite - SMILES: CC(N(P(O[C@H]1[C@H]([C@H](N2C(N=C(C(C)=C2)NC(C3=CC=CC=C3)=O)=O)O[C@@H]1COC(C4=CC=C(C=C4)OC)(C5=CC=C(C=C5)OC)C6=CC=CC=C6)O[Si](C)(C(C)(C)C)C)OCCC#N)C(C)C)C
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Alirocumab is an anti-PCSK9 human monoclonal antibody Alirocumab inhibits PCSK9 Alirocumab reduces NLRP3 inflammasome regulates Nrf2/HO-1 HMGB1/NF- B and Fractalkine/CX3CR1 Alirocumab increases the ability of the liver to bind LDL-cholesterol (LDL-C) and reduces levels of LDL-C in blood Alirocumab improves atherosclerosis and inflammation[1][2][3][4][5][6][7][8][9][10][11]
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Hh-Ag1.5 is a potent small-molecule agonist of the Hedgehog signaling pathway (EC50 ≈ 1 nM) for use in in vitro and in vivo pathway activation and stem-cell reprogramming studies. Supplied as a white to off-white solid at high purity, it is formulated for research and preclinical applications.
Potency: EC50 1 nM (Hedgehog)
CAS number: 612542-14-0
Molecular formula: C28H26ClF2N3OS
Molecular weight: 526.04
Purity: 99.9%
Appearance: white to off-white solid
Solubility: DMSO 50 mg/mL (use fresh DMSO; ultrasonic may be required)