Phenols
eMolecules 3-Chloro-4-hydroxy-5-methoxyphenylboronic acid, pinacol ester | 1003298-84-7 | 5G | Purity: 96%
Combi-Blocks | 3-Chloro-4-hydroxy-5-methoxyphenylboronic acid, pinacol ester | 5G | 1003298-84-7 | MFCD05663844
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Apexbio Technology LLC EZ Cap Mouse CD86 mRNA (m1Ψ HA tag) 100ug (1mg/mL)
Mouse CD86 mRNA encodes CD86P primarily expressed on antigen-presenting cells It binds to CD28 and CTLA-4 receptors on T cells to regulate T-cell activation and immune responses The interaction between CD86 and CD28 promotes T-cell activation and proliferation whereas its binding to CTLA-4 inhibits T-cell activity maintaining immune system balance Expression and function of CD86 are critical in various immune responses including infections tumor immunity and autoimmune diseases CD86 activity may offer novel therapeutic strategies for various immune-related disorders EZ Cap Mouse CD86 mRNA (m1 HA tag) is provided at 1 mg/mL expressing mouse-derived CD86 cytokine fused with HA tag facilitating subsequent detection It contains a cap 1 structure generated via co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Apexbio Technology LLC EZ Cap Mouse RLI mRNA (m1Ψ) 1mg (1mg/mL)
Mouse RLI mRNA encodes a fusion protein composed of interleukin-15 (IL-15) fused to the sushi domain of its receptor IL-15R representing an innovative immunotherapeutic agent As a crucial cytokine IL-15 stimulates proliferation of natural killer (NK) cells and T cells thus enhancing immune responses against tumor cells and viruses The IL-15/IL-15R -sushi fusion protein shows promise in cancer immunotherapy by enhancing immune cell function and promoting clearance of tumor cells EZ Cap Mouse RLI mRNA (m1 )is supplied at 1 mg/mL expresses mouse-derived RLI fusion protein It contains a cap 1 structure generated through co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Cambridge Isotope Laboratories 1 2 4 6 9-PentaCDF (unlabeled) 25 ng/mL in nonane 0 2 mL
1 2 4 6 9-PentaCDF (unlabeled) 25 ng/mL in nonane 0 2 mL
Medchemexpress LLC Cyclophosphamide hydrate | 6055-19-2 | 99.9% | 500 MG
Cyclophosphamide hydrate is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities. It induces outer membrane blebbing, leads to DNA fragmentation, and induces cleavage of caspase 3 and caspase 7 substrate PARP in 9L/P450 cells. In C3H mice bearing SW1 tumors, it increased the percentage of cells that stained for CD3, CD4, or CD8 in both spleens and tumors.
- Acts as a synthetic alkylating agent
- Exhibits antineoplastic and immunosuppressive activities
- Induces DNA fragmentation and caspase cleavage
- Increases immune cell markers in spleens and tumors
Medchemexpress LLC N-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2-yl)ethyl)phenyl)-2-(pyridin-4-yl)quinazolin-4-amine | 2050747-49-2 | 98.8% | 517.62 g/mol | C32H31N5O2 | 1 ML
P-gp inhibitor 1 is a research reagent described as a novel small molecule inhibitor that reverses P-glycoprotein-mediated multidrug resistance. It is supplied in solution or solid form for laboratory use, with high purity and defined storage recommendations for stability.
- Potent P-gp inhibition with low cytotoxicity in cell assays.
- Demonstrated activity at low nanomolar EC50 values.
- Available as a 10 mM solution in DMSO or as solid mg quantities.
- High purity suitable for research applications.
- Stable under recommended storage conditions for short- and long-term use.
- Intended for laboratory research use only, not for clinical use.