Rhosin hydrochloride is a potent and specific inhibitor of the RhoA subfamily Rho GTPases. It works by binding to RhoA, inhibiting its interaction with GEF proteins. This compound does not interact with Cdc42, Rac1, or LARG. It promotes stress resiliency and induces cell apoptosis, making it suitable for various research applications.
- Specifically inhibits RhoA subfamily Rho GTPases
- Induces cell apoptosis
- Promotes stress resiliency by enhancing D1-MSN plasticity
- Reduces hyperexcitability
- Does not interact with Cdc42, Rac1, or LARG