Phenols
Medchemexpress LLC Oncaspar | 130167-69-0 | 99.9% | 1 MG
Oncaspar (PEG-L-asparaginase) is a pegylated form of L-asparaginase derived from Escherichia coli. It functions by breaking down asparagine in the bloodstream, playing a crucial role in acute lymphoblastic leukemia (ALL) research through asparagine hydrolysis and activation of the integrated stress response (ISR) pathway.
- Pegylated form of L-asparaginase.
- Breaks down asparagine in the bloodstream.
- Important for acute lymphoblastic leukemia (ALL) research.
- Suitable for ELISA, FACS, and functional assays.
- Can be reconstituted or diluted with sterile PBS or saline.
- Appears as a colorless to light yellow liquid.
Medchemexpress LLC GeA-69 | 2143475-98-1 | 99.9% | 300.35 | 10 MG
GeA-69 is a selective, allosteric inhibitor of poly-adenosine-diphosphate-ribose polymerase 14 (PARP14) targeting macrodomain 2 (MD2). It is involved in DNA damage repair mechanisms and prevents the recruitment of PARP14 MD2 to sites of laser-induced DNA damage. This product is for research use only.
- Selective, allosteric inhibitor of PARP14 targeting MD2.
- Involved in DNA damage repair mechanisms.
- Prevents recruitment of PARP14 MD2 to sites of laser-induced DNA damage.
- Highly cell permeable.
- Exhibits moderate cytotoxicity against normal cells.
Medchemexpress LLC Nafcillin sodium monohydrate | 7177-50-6 | 98.1% | 5 G
Nafcillin sodium monohydrate is an antibiotic and a reversible inhibitor of β-lactamase. It can be used for the research of staphylococcal infections.
- Antibiotic
- Reversible inhibitor of β-lactamase
- Used for research of staphylococcal infections
- Exhibits bactericidal activity against methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant S. aureus (MRSA)
Medchemexpress LLC Cinchophen | 132-60-5 | 99.9% | 25 G
Cinchophen is a potent and orally active non-steroidal anti-inflammatory agent that exhibits analgesic and antimicrobial effects. This compound is utilized in research for conditions such as arthritis and various liver diseases.
- Potent and orally active non-steroidal anti-inflammatory agent
- Exhibits analgesic effects
- Possesses antimicrobial properties
- Used in research for arthritis and liver diseases
- Targets bacterial and anti-infection pathways
- Appears as a white to off-white solid
- For research use only
Medchemexpress LLC Busulfan | 55-98-1 | 99.9% | 25 G
Busulfan is a potent alkylating antineoplastic agent that causes DNA damage by cross-linking DNAs and DNA and proteins. It inhibits thioredoxin reductase and induces apoptosis, functioning as an immunosuppressive and myeloablative chemotherapeutic agent. This product is intended for research and analytical applications.
- Causes DNA damage by cross-linking DNAs and DNA and proteins
- Inhibits thioredoxin reductase
- Induces apoptosis
- Functions as an immunosuppressive and myeloablative chemotherapeutic agent
- Targets DNA alkylator/crosslinker, apoptosis, and various diseases
- Used to induce aplastic anemia models in research
Medchemexpress LLC Ibandronate (Sodium Monohydrate) | 138926-19-9 | 98.0% | 1 ML
Ibandronate Sodium Monohydrate is an orally active, selective inhibitor of farnesyl pyrophosphate synthase (FPP synthase). It works by blocking the mevalonate pathway, which inhibits the modification of small GTPases, leading to tumor cell apoptosis and reduced bone resorption. This compound also inhibits tumor cell proliferation, promotes FAS gene expression, and can provide synergistic anti-tumor effects when combined with anti-estrogen compounds. It is commonly used in research related to osteoporosis and bone metastatic tumors, including breast cancer bone metastasis.
- Orally active and selective FPP synthase inhibitor
- Blocks mevalonate pathway
- Induces tumor cell apoptosis
- Inhibits bone resorption
- Inhibits tumor cell proliferation
- Promotes expression of pro-apoptotic gene FAS
- Useful for osteoporosis and bone metastatic tumor research
Medchemexpress LLC Ethambutol dihydrochloride | 1070-11-7 | 99.9% | 250 MG
Ethambutol dihydrochloride is an antimycobacterial compound that prevents cell wall formation by inhibiting arabinosyltransferase activity. It can be used to establish animal models of hyperuricemia and optic neuropathy.
- Antimycobacterial compound
- Prevents cell wall formation
- Inhibits arabinosyltransferase activity
- Establishes animal models of hyperuricemia
- Establishes animal models of optic neuropathy
Medchemexpress LLC Pravastatin sodium | 81131-70-6 | 99.4% | 25 G
Pravastatin sodium is an HMG-CoA reductase inhibitor that targets sterol synthesis with an IC50 of 5.6 μM. It belongs to the drug class of statins, which are used to lower cholesterol and prevent cardiovascular disease, often in conjunction with diet, exercise, and weight loss.
- Effectively inhibits sterol synthesis
- Intended for research purposes
- High purity
- Soluble in DMSO (100 mg/mL) and H2O (≥ 50 mg/mL)
- Used in cellular steroidogenesis inhibition studies in HepG2 cells
- Cited in various publications for cell proliferation/viability assays, RT-PCR, and cell imaging/staining
Medchemexpress LLC Pravastatin sodium (CS-514 sodium) | 81131-70-6 | 99.38% | 10 G
Pravastatin sodium (CS-514 sodium) is an HMG-CoA reductase inhibitor, primarily used for research purposes. It targets sterol synthesis with an IC50 of 5.6 μM and belongs to the statin drug class. It is indicated for lowering cholesterol and preventing cardiovascular disease when used in combination with diet, exercise, and weight-loss.
- HMG-CoA reductase inhibitor
- Targets sterol synthesis with an IC50 of 5.6 μM
- Used for research purposes
- Inhibits cellular steroidogenesis in HepG2 cells with an IC50 of 1.37 μM
- Inhibits cholesterol synthesis from [14C]-Acetate in rat hepatocytes with an IC50 of 100 nM
Medchemexpress LLC Taurine | 107-35-7 | 99.9% | 100 G
Taurine is a sulfur-containing amino acid and an organic osmolyte involved in cell volume regulation. It provides a substrate for the formation of bile salts and plays a role in modulating intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes.
- Involved in cell volume regulation
- Provides a substrate for bile salt formation
- Modulates intracellular free calcium concentration
- Activates autophagy in adipocytes
- One of the most abundant amino acids in the brain and spinal cord, leukocytes, heart, muscle cells, and retina
- Exhibits diverse biological actions including protection against ischemia-reperfusion injury
- Offers antioxidant, antiatherogenic, and blood pressure-lowering effects
Medchemexpress LLC Riboflavin | 83-88-5 | 99.89% | 25 G
Riboflavin, also known as Vitamin B2 or E101, is an orally active and readily absorbed micronutrient. It acts as a precursor to flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which serve as crucial coenzymes for numerous enzymatic reactions and play a vital role in metabolic functions by mediating electron transfer in biological oxidation-reduction reactions.
- Demonstrates a potent cytotoxic effect on HL60 cells after UV irradiation.
- Enhances cell viability and glutathione reductase activity in HepG2 cells.
- Promotes growth in Swiss albino mice.
- Produces antinociceptive, antihyperalgesic, and anti-inflammatory effects in various rat models.
- Inhibits the nociceptive response in mice experiencing acetic acid-induced constriction.
Medchemexpress LLC (E)-Fenpyroximate | 134098-61-6 | MFCD00274596 | 99.8% | 1 ML
(E)-Fenpyroximate is a potent acaricide that functions as a mitochondrial NADH:ubiquinone reductase inhibitor. This compound is widely used as an acaricide, miticide, and insecticide, and is registered for various plant commodities. It is also approved in the EU as an active substance and is currently being investigated for malaria control.
- Potent acaricide
- Functions as a mitochondrial NADH:ubiquinone reductase inhibitor
- Used as a miticide and insecticide
- Registered for use on various plant commodities
- Approved in the EU as an active substance
- Investigated for malaria control
- Appearance as a white to off-white solid
- Molecular formula C24H27N3O4
Medchemexpress LLC Oxacillin sodium salt | 1173-88-2 | 99.5% | 10 MM 1 ML
Oxacillin sodium salt is an orally active synthetic penicillin that demonstrates good bactericidal activity against staphylococci and other gram-positive pathogens. It is intended for research use only.
- Orally active synthetic penicillin
- Good bactericidal activity against staphylococci
- Effective against gram-positive pathogens
Medchemexpress LLC Bucladesine (sodium) | 16980-89-5 | 99.4% | 1 ML
Bucladesine sodium is a stabilized cyclic AMP (cAMP) analog that acts as a selective PKA activator. It increases intracellular cAMP levels and also functions as a phosphodiesterase (PDE) inhibitor. This compound possesses anti-inflammatory activity and has been utilized for impaired wound healing research.
- Acts as a selective PKA activator
- Increases intracellular cAMP levels
- Functions as a phosphodiesterase (PDE) inhibitor
- Exhibits anti-inflammatory activity
- Can be used for impaired wound healing research
- Increases choline acetyltransferase (ChAT) and vesicular acetylcholine transporter (VAChT) mRNA levels in PC12 cells
- Improves spatial memory retention in vivo studies
- Supplied as a white to off-white solid
- Soluble in water and DMSO
Medchemexpress LLC Methicillin sodium salt | 132-92-3 | 98.1% | 1 ML
Methicillin sodium salt is a β-lactam, semi-synthetic antibiotic related to penicillin antibiotics. It inhibits penicillin-binding proteins involved in the synthesis of peptidoglycan. This compound inhibits *S. aureus* with a MIC value of 2.1 μg/mL and is suitable for inflammation research.
- Semi-synthetic β-lactam antibiotic
- Inhibits penicillin-binding proteins
- Effectively eliminates S. aureus
- Suitable for inflammation research
- Improves survival in infected animal models