Phenols
Medchemexpress LLC Pravastatin (sodium) | 81131-70-6 | 99.0% | 5 G
Pravastatin sodium is an HMG-CoA reductase inhibitor against sterol synthesis with an IC50 of 5.6 μM. It is a statin used in combination with diet, exercise, and weight-loss for lowering cholesterol and preventing cardiovascular disease.
- Inhibits HMG-CoA reductase.
- For research use only.
- IC50 for inhibiting cellular steroidogenesis in HepG2 hepatocytes is 1.37 μM.
- IC50 for antimalarial activity against Plasmodium berghei NK65 in HepG2 hepatocytes is > 200 μM (after 48 hours by RT-PCR).
- Inhibits cholesterol synthesis in isolated rat hepatocytes with an IC50 of 0.1 μM.
- Inhibits cholesterol synthesis from [14C]- Acetate in hepatocytes of rats with an IC50 of 100 nM.
Medchemexpress LLC Salicylamide | 65-45-2 | 99.7% | 25 G
Salicylamide is an inhibitor of microsomal UDP-glucuronosyltransferase. It also acts as an analgesic and anti-pyretic agent. Studies indicate that salicylamide treatment inhibits bacterial growth and affects radiosulfate levels in maternal serum and placenta, thereby affecting the incorporation of radiosulfate into fetal skeletal GAGs and calcium content of fetal limb bones.
- Inhibitor of microsomal UDP-glucuronosyltransferase
- Analgesic and anti-pyretic agent
- Inhibits bacterial growth
- Decreases radiosulfate levels in maternal serum and placenta
- Impairs incorporation of radiosulfate into fetal skeletal GAGs
- Decreases calcium content of fetal limb bones
eMolecules 3-Fluoro-4-iodophenol | 122927-84-8 | MFCD12407087 | 1g
Ambeed | 3-Fluoro-4-iodophenol | 1g | 531647290 | A181746 | | 122927-84-8 | MFCD12407087 | 238.000 | C6H4FIO
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Medchemexpress LLC Tolperisone hydrochloride | 3644-61-9 | 99.8% | 5 MG
Tolperisone hydrochloride | 3644-61-9 | 99.8% | 5 MG
Medchemexpress LLC Olopatadine (hydrochloride) | 140462-76-6 | 99.8% | 1 ML
Olopatadine (hydrochloride) | 140462-76-6 | 99.8% | 1 ML
Medchemexpress LLC SB-747651A (dihydrochloride) | 1781882-72-1 | 99.14% | 415.32 | 25 MG
SB-747651A dihydrochloride is an ATP-competitive inhibitor of mitogen- and stress-activated kinase 1 (MSK1) with an IC₅₀ of 11 nM. It also inhibits PRK2, RSK1, p70S6K, and ROCK-II. This compound is used in inflammation research.
- ATP-competitive MSK1 inhibitor
- Inhibits PRK2, RSK1, p70S6K, and ROCK-II
- Suitable for inflammation research
- Modulates chemokine-induced neutrophil recruitment
- Affects neutrophil extravasation in acute inflammation models
Medchemexpress LLC Br-PEG4-OH | 85141-94-2 | 98.2% | 5 G
Br-PEG4-OH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two different ligands linked together; one targets an E3 ubiquitin ligase and the other targets the protein of interest. Their function is to leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Peg-based protac linker
- Utilized in the synthesis of protacs
- Leverages the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Bromo-PEG1-CH2COOH | 1135131-50-8 | ≥97.0% | 1 G
Bromo-PEG1-CH2COOH is a PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PROTAC linker for synthesis of PROTACs
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC (2,4,6-Trimethyl-phenoxy)-acetic acid | 13333-81-8 | MFCD00224887 | 98.0% | 194.23 g/mol | C11H14O3 | 250 MG
2-(2,4,6-Trimethylphenoxy)acetic acid is an organic research chemical described as having herbicide activity. It is supplied in laboratory-scale quantities for research use. Key identifiers include CAS 13333-81-8, formula C11H14O3, molecular weight 194.23 g/mol, and typical purity 98%.
- Organic compound reported to have herbicide activity.
- Supplied in laboratory pack sizes for experimental use.
- Typical high purity supports reproducible results.
- Chemical formula C11H14O3 and molecular weight 194.23 g/mol for reference.
- Product datasheet provides handling and safety information.
Medchemexpress LLC BOP sodium | 1947348-42-6 | 99.3% | 1 MG
BOP sodium is a potent and selective dual α9β1/α4β1 integrin inhibitor with Kd values in the picomolar range. It shows rapid and preferential mobilization of hematopoietic stem cell (HSC) and progenitors. It has little inhibitory activity on α4β7, α1β1, α2β1, and α5β1, αIIBβ3 integrins.
- Potent and selective dual α9β1/α4β1 integrin inhibitor
- Kd values in the picomolar range
- Rapid and preferential mobilization of hematopoietic stem cells (HSC) and progenitors
- Exhibits little inhibitory activity on α4β7, α1β1, α2β1, and α5β1, αIIBβ3 integrins