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Aromatic organic compounds that consist of a phenyl functional group (−C6H5) bonded to a hydroxyl functional group (−OH). Includes compounds with more substitutions and derivatives.
Biotin-4-aminophenol (CAS No 901770-40-9) is a chemical compound used in biomedical research originating from the field of biochemistry It operates primarily through biotinylation affecting pathways involved in cellular signaling and transport In vitro it demonstrates activity in the nanomolar to low micromolar range making it suitable for precise biological studies Typical applications include experiments in various cell models animal studies and drug screening processes where it serves as a critical reagent for labeling and tracking molecules Experimental concentrations typically depend on the specific research design allowing researchers to tailor its use to their particular study needs
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LY266097 hydrochloride is a research-grade selective 5-HT2B receptor antagonist supplied as the hydrochloride salt. It is a high-purity solid used in pharmacology and neuropharmacology studies to probe serotonin 5-HT2 receptor signaling and related behavioral and biochemical effects.
Selective 5-HT2B antagonist with high affinity.
High purity suitable for biochemical and cellular assays.
Supplied as a stable solid for controlled storage.
Well-characterized identifiers: CAS 172895-39-5; molecular weight 407.33 g/mol.
Storage conditions compatible with long-term sample integrity.
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CX-6258 hydrochloride is a potent and kinase selective pan-Pim kinases inhibitor, with IC50s of 5 nM, 25 nM and 16 nM for Pim-1, Pim-2 and Pim-3, respectively. For research use only. We do not sell to patients.
Potent and kinase selective pan-Pim kinases inhibitor.
Inhibits phosphorylation of pro-survival proteins Bad and 4E-BP1 at specific Pim kinase sites.
Exhibits robust in vivo efficacy in Pim kinases driven tumor models.
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A simple aliphatic amine that was once marketed as a nasal decongestant but is now sold as a bodybuilding supplement; sold as a mild stimulant in the form of party pills; intended for forensic or research purposes
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SKI-I is a small-molecule sphingosine kinase inhibitor used in biochemical and cellular research to probe sphingolipid signaling and apoptosis pathways. It is supplied as a purified research reagent with stated solubility and storage recommendations for laboratory use only.
Research-grade sphingosine kinase inhibitor for biochemical and cellular studies.
High reported purity of 99.14%.
Molecular weight 406.44 and formula C25H18N4O2.
Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
Available in multiple pack sizes, including 100 MG.
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ZLN024 hydrochloride is an allosteric activator of AMPK, directly stimulating active AMPK heterotrimers as well as inactive α1 subunit truncations. This activation requires pre-phosphorylation of Thr-172 by upstream kinases and protects AMPK Thr-172 from dephosphorylation. It activates AMPK in L6 myotubes, promoting glucose uptake and fatty acid oxidation without altering the ADP/ATP ratio. In vivo studies showed improved glucose tolerance and reduced fasting blood glucose in C57BKS db/db mice.
Allosterically stimulates active AMPK heterotrimers.
Activates AMPK in L6 myotubes.
Stimulates glucose uptake and fatty acid oxidation.
Improves glucose tolerance.
Reduces fasting blood glucose.
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Mepazine hydrochloride is a small-molecule MALT1 protease inhibitor used in cellular and biochemical research to study apoptosis and signaling pathways.
High listed purity (99.25%).
Molecular weight 346.92 g/mol and formula C19H23ClN2S.
Available in small research pack sizes including 10 MG.
Suitable for cellular assays probing MALT1 activity and apoptosis.
Storage: solid at 4°C; solutions at -80°C for long-term, sealed and protected from moisture.
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Clevidipine-d7 (CAS No 2747918-66-5) is an isotopically labeled compound used primarily in biomedical research As a dihydropyridine calcium channel blocker it targets calcium channels leading to vasodilation This mechanism is pivotal in studying cardiovascular functions and drug interactions In vitro Clevidipine-d7 demonstrates activity in the nanomolar to low micromolar range making it a valuable tool in pharmacokinetics and metabolic studies Its stable isotope labeling provides advantages in mass spectrometry for quantifying drug metabolism Typical applications include use in cellular models to examine calcium-dependent pathways as well as in animal studies for evaluating hemodynamic effects and during drug screening processes Experimental concentrations typically depend on the specific research design
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