Hyaluronan-binding peptide, biotin labeled TFA is a biologically active peptide. This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan found in the extracellular matrix and on cell surfaces. HA plays roles in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.
- Biologically active peptide
- Biotinylated through a C-terminal GGGSK linker
- Blocks HA binding to CD44 receptors
- Inhibits T cell proliferation