Azoles
Cayman Chemical 2-methyl-4-phenyl ThIazole 1g
A synthetic intermediate useful for pharmaceutical synthesis
Chemscene ChemScene | 4-Methyl-1,3-oxazole-5-carboxylic acid | 10G | CS-W008834 | 0.98 | 2510-32-9| MFCD01571070 | 127.099
ChemScene | 4-Methyl-1,3-oxazole-5-carboxylic acid | 10G | CS-W008834 | 0.98 | 2510-32-9| MFCD01571070 | 127.099
Chemscene ChemScene | 4-Methyl-1,3-oxazole-5-carboxylic acid | 25G | CS-W008834 | 0.98 | 2510-32-9| MFCD01571070 | 127.099
ChemScene | 4-Methyl-1,3-oxazole-5-carboxylic acid | 25G | CS-W008834 | 0.98 | 2510-32-9| MFCD01571070 | 127.099
Medchemexpress LLC Phthalazinone pyrazole | 880487-62-7 | MFCD28399120 | 98.0% | 317.34 | C18H15N5O | 10MG
Phthalazinone pyrazole is a potent, selective, orally active small-molecule inhibitor of Aurora-A kinase used for research in cell biology and oncology. It has a biochemical IC50 of 0.031 μM against Aurora-A and shows cellular activity in multiple cancer cell lines.
- Potent Aurora-A kinase inhibition (IC50 0.031 μM).
- Demonstrated cellular activity in COLO 205, HCT-116, and MCF7 cell lines.
- High purity suitable for research (98.0%).
- Well-characterized physicochemical properties (C18H15N5O; MW 317.34).
- Available as solid and solution formats for assay flexibility.
- Supplied with a datasheet containing analytical and handling information.
Medchemexpress LLC Filastatin | 431996-53-1 | MFCD03058358 | 99.3% | 359.8 g/mol | C18H18ClN3O3 | 50MG
Filastatin is a small-molecule antifungal research reagent that inhibits Candida albicans filamentation and adhesion. It blocks the yeast-to-hyphal morphological transition and inhibits adhesion across multiple pathogenic Candida species (IC50 ≈ 3 μM in a GFP-based adhesion assay), making it suitable for in vitro studies of fungal morphogenesis and host-pathogen interactions.
- Inhibits Candida albicans filamentation and adhesion.
- Reduces fungal adhesion to surfaces and human cells.
- Blocks the yeast-to-hyphal morphological transition.
- Useful for in vitro antifungal and pathogenesis research.
- High purity appropriate for biochemical assays.
Medchemexpress LLC YL-5092 | 3056857-07-6 | 99.8% | 441.43 | 1 ML
YL-5092 is a selective YT521-B homology (YTH) domain-containing protein 1 (YTHDC1) inhibitor with an IC50 of 7.4 nM and a KD of 29.6 nM. It can suppress cancer cell proliferation and induce cell G0/G1 phase arrest and apoptosis. YL-5092 is used for cancer research, including acute myeloid leukemia (AML).
- Selectively inhibits YT521-B homology (YTH) domain-containing protein 1.
- Suppresses cancer cell proliferation.
- Induces cell G0/G1 phase arrest.
- Promotes apoptosis in cancer cells.
- Impairs leukemogenesis and improves survival rates in mouse tumor models.
- Reduces leukemia infiltration in peripheral blood, spleen, and bone marrow.
- Decreases the expression of YTHDC1 target genes like MYC, FOXM1, GINS1, MCM2, MCM4, and MCM5.
eMolecules 4-(2-Amino-1,3-thiazol-4-yl)benzoic acid | 216959-94-3 | MFCD01460736 | 1g
Combi-Blocks | 4-(2-Amino-1,3-thiazol-4-yl)benzoic acid | 1g | 448009810 | ST-6032 | 97.000 | 216959-94-3 | MFCD01460736 | 220.250 | C10H8N2O2S
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Medchemexpress LLC Varespladib methyl | 172733-08-3 | 99.9% | 394.42 | 1 ML
Varespladib methyl (A-002; LY333013) is a selective inhibitor of group II secretory phospholipase A2 (PLA2). It is an orally-administered methyl ester pro-drug that is metabolized to LY315920. It demonstrates high-level secretory PLA2 (sPLA2) inhibition at nanomolar and picomolar concentrations against 28 medically important snake venoms from six continents.
- Selective inhibitor of group II secretory phospholipase A2 (PLA2).
- Orally-administered methyl ester pro-drug.
- Metabolized to LY315920.
- Exhibits high-level sPLA2 inhibition against 28 snake venoms.
- Purity: 99.90%.
Chem-Impex International, Inc. 1-Methylindazole-6-boronic acid | MFCD09870053 | 1G
1-Methylindazole-6-boronic acid, MFCD09870053, 1G
![eMolecules 5-chloro-[1,2,4]triazolo[4,3-a]pyridine | 27187-13-9 | MFCD11109431 | 5g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502188043.JPG-250.jpg)
eMolecules 5-chloro-[1,2,4]triazolo[4,3-a]pyridine | 27187-13-9 | MFCD11109431 | 5g
Combi-Blocks, Inc. | 5-chloro-[1,2,4]triazolo[4,3-a]pyridine | 5g | 603142205 | HC-2343 | 95.000 | 27187-13-9 | MFCD11109431 | 153.570 | C6H4ClN3
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