Azoles
eMolecules 107259-06-3 | (1-Formyl-cyclopropyl)-carbamic acid tert-butyl ester | Combi-Blocks | MFCD10697899 | 185.223 | C9H15NO3 | 97.000 | CC(C)(C)OC(=O)NC1(CC1)C=O | 5g | 439372821
(1-Formyl-cyclopropyl)-carbamic acid tert-butyl ester | Combi-Blocks | 107259-06-3 | MFCD10697899 | 185.223 | C9H15NO3 | 97.000 | CC(C)(C)OC(=O)NC1(CC1)C=O | 5g | 439372821
Apexbio Technology LLC TH-302 918633-87-1 200mg
TH-302 (CAS 918633-87-1) is a hypoxia-activated prodrug comprising a 2-nitroimidazole moiety linked to a brominated isophosphoramide mustard Under severe hypoxic conditions (approximately 0 1% O ) TH-302 undergoes bioreductive activation releasing the cytotoxic alkylating agent Br-IPM selectively within hypoxic tumor microenvironments In vitro studies demonstrate markedly increased cytotoxicity against tumor cell lines under hypoxia with IC50 values ranging from 0 1 to 0 8 M for H460 Caki-1 SK-MEL-5 DU145 and HCT116 cells while IC50 values exceed 40 M in normoxic conditions In H460 xenograft mouse models TH-302 induces dose-dependent tumor growth inhibition without hematological toxicity and increases H2AX-positive cells indicating DNA damage TH-302 is utilized to investigate tumor hypoxia-targeting therapies and mechanisms of selective cytotoxicity
eMolecules 1313403-49-4 | Medchem Express | 7-BIA | 5mg | 527574372 | HY-115496 | 294.303 | C15H18O6
Medchem Express | Compound C108 | 5mg | 785215271 | HY-131649 | 15533-09-2 | MFCD00565556 | 270.288 | C15H14N2O3
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eMolecules Building Block Tool<|a>
![eMolecules 61-82-5 | 1H-1,2,4-Triazole-3-amine | Matrix Scientific | MFCD00005230 | 84.082 | C2H4N4 | 97.000 | Nc1nc[nH]n1 | 1g | 389724640](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00128114-389724640.PNG-250.jpg)
eMolecules 61-82-5 | 1H-1,2,4-Triazole-3-amine | Matrix Scientific | MFCD00005230 | 84.082 | C2H4N4 | 97.000 | Nc1nc[nH]n1 | 1g | 389724640
1H-1,2,4-Triazole-3-amine | Matrix Scientific | 61-82-5 | MFCD00005230 | 84.082 | C2H4N4 | 97.000 | Nc1nc[nH]n1 | 1g | 389724640
![eMolecules 120503-69-7 | N6-CYCLOPROPYL-9H-PURINE-2,6-DIAMINE | AstaTech | MFCD12215664 | 190.210 | C8H10N6 | 95.000 | Nc1nc(NC2CC2)c2nc[nH]c2n1 | 0.25g | 443847625](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502462935.JPG-250.jpg)
eMolecules 120503-69-7 | N6-CYCLOPROPYL-9H-PURINE-2,6-DIAMINE | AstaTech | MFCD12215664 | 190.210 | C8H10N6 | 95.000 | Nc1nc(NC2CC2)c2nc[nH]c2n1 | 0.25g | 443847625
N6-CYCLOPROPYL-9H-PURINE-2,6-DIAMINE | AstaTech | 120503-69-7 | MFCD12215664 | 190.210 | C8H10N6 | 95.000 | Nc1nc(NC2CC2)c2nc[nH]c2n1 | 0.25g | 443847625
Strem, An Ascensus Company CAS# 1034449-15-4. 2g. 1,3-Dicyclohexylbenzimidazolium chloride, min. 97%. MFCD08705248
CAS# 1034449-15-4. 2g. 1,3-Dicyclohexylbenzimidazolium chloride, min. 97%. MFCD08705248. Molecular Weight: 318.88. Molecular Formula: C19H27ClN2. Color/form: white to off-white solid Strem# 07-4015. http://www.strem.com/catalog/v/07-4015/
