Also available in 1 mL, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. VH-298 is a potent inhibitor of VHL that stabilizes HIF-alpha and elicits a hypoxic response via a different mechanism, that is the blockade of the VHLHIF-alpha protein-protein interaction downstream of HIF-alpha hydroxylation by PHD enzymes. Purity 100%