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Azoles

Organic compounds that consist of five-membered heterocyclic molecules containing a nitrogen atom and at least one other non-carbon atom as part of the ring.
Thiazoles (4)
Imidazoles (3)
Pyrazoles (1)
Triazoles (1)

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1

2,3-Dimethyl-1-propylimidazolium Bis(trifluoromethanesulfonyl)imide 98.0+%, TCI America™

CAS: 169051-76-7 Molecular Formula: C10H15F6N3O4S2 Molecular Weight (g/mol): 419.357 MDL Number: MFCD03788922 InChI Key: XOZHIVUWCICHSQ-UHFFFAOYSA-N Synonym: 1,2-Dimethyl-3-propylimidazolium Bis(trifluoromethanesulfonyl)imide PubChem CID: 11750474 IUPAC Name: bis(trifluoromethylsulfonyl)azanide;1,2-dimethyl-3-propylimidazol-1-ium SMILES: CCCN1C=C[N+](=C1C)C.C(F)(F)(F)S(=O)(=O)[N-]S(=O)(=O)C(F)(F)F

PubChem CID 11750474
CAS 169051-76-7
Molecular Weight (g/mol) 419.357
MDL Number MFCD03788922
SMILES CCCN1C=C[N+](=C1C)C.C(F)(F)(F)S(=O)(=O)[N-]S(=O)(=O)C(F)(F)F
Synonym 1,2-Dimethyl-3-propylimidazolium Bis(trifluoromethanesulfonyl)imide
IUPAC Name bis(trifluoromethylsulfonyl)azanide;1,2-dimethyl-3-propylimidazol-1-ium
InChI Key XOZHIVUWCICHSQ-UHFFFAOYSA-N
Molecular Formula C10H15F6N3O4S2
2

Medchemexpress LLC PNR-7-02 | 1633660-76-0 | 98.0% | 445.92 | C24H16ClN3O2S | 5 MG
SDP

A small-molecule inhibitor of DNA polymerase eta (Pol η) supplied for research use. Provided as a solid in milligram quantities for in vitro and preclinical studies, it is suitable for mechanism-of-action experiments and combination cytotoxicity assays.

  • High purity: 98.0%.
  • Molecular weight 445.92.
  • Chemical formula C24H16ClN3O2S.
  • Provided in a 5 MG vial suitable for laboratory assays.
  • Intended for in vitro pharmacology and mechanism-of-action studies.

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3

Medchemexpress LLC PNR-7-02 | 1633660-76-0 | 98.0% | 445.92 | C24H16ClN3O2S | 50 MG
SDP

PNR-7-02 is a small-molecule research inhibitor of DNA polymerase eta (Pol η). It is an indole thio-barbituric acid derivative reported to inhibit Pol η (IC50 ≈ 8 μM), with activity against hRev1 and DNA polymerase λ, and reported synergy with cisplatin in certain cancer cell lines.

  • Purity 98.0%.
  • Molecular weight 445.92.
  • Chemical formula C24H16ClN3O2S.
  • Appearance solid.
  • Recommended solvent DMSO; solubility note: 1 mg/mL, ultrasonic and warming, heat to 60°C.
  • Storage powder: -20°C for 3 years; in solvent: -80°C for 6 months.

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4

Medchemexpress LLC PNR-7-02 | 1633660-76-0 | 98.0% | 445.92 | C24H16ClN3O2S | 10 MG
SDP

PNR-7-02 is a small-molecule Pol η (DNA polymerase eta) inhibitor provided for preclinical biochemical and cell-based research. It is supplied as a solid research compound and is not for human or veterinary use.

  • Purity 98.0%.
  • Molecular weight 445.92 g/mol.
  • Chemical formula C24H16ClN3O2S.
  • CAS number 1633660-76-0.
  • Soluble in dimethyl sulfoxide (DMSO).
  • Pack size 10 mg.
  • Intended for research use only.

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5

eMolecules​ 8-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRAZINE | 1367824-76-7 | MFCD22059055 | 50mg

AstaTech | 8-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRAZINE | 50mg | 562547304 | O11668 | 95.000 | 1367824-76-7 | MFCD22059055 | 199.011 | C5H3BrN4

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6

Medchemexpress LLC PNR-7-02 | 1633660-76-0 | 98.0% | 445.92 g·mol⁻¹ | C24H16ClN3O2S | 25 MG
SDP

PNR-7-02 is a small-molecule inhibitor of DNA polymerase eta (Pol η) used in research on translesion synthesis and polymerase-mediated drug resistance. It is an indole thio-barbituric acid derivative reported to inhibit Pol η (IC50 ≈ 8 μM) and to act synergistically with cisplatin in cancer cell lines.

  • Inhibits Pol η with reported IC50 ≈ 8 μM
  • Also shows activity against hRev1 and hpol λ
  • High purity (98.0%) suitable for biochemical assays
  • Available as a 25 MG package, other sizes available
  • Indole thio-barbituric acid scaffold, useful as a small-molecule probe
  • For research use only; not for human or clinical use

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7

Medchemexpress LLC 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-((3S)-3-piperidinylmethyl)oxy)-2-methyl-3-butyn-2-ol | 937174-76-0 | MFCD14105605 | 98.5% | 425.48 g/mol | C21H27N7O3 | 25 MG
SDP

GSK-690693 is a small-molecule, ATP-competitive pan-Akt inhibitor used for biochemical and cell-based research into PI3K/Akt signaling. It inhibits Akt1, Akt2, and Akt3 with low nanomolar potency (IC50s: 2 nM, 13 nM, 9 nM). The compound has molecular formula C21H27N7O3 and a molecular weight of 425.48 g/mol, and is supplied as a high-purity solid for laboratory research.

  • Inhibits Akt1, Akt2, and Akt3 with low nanomolar potency.
  • ATP-competitive mechanism of action.
  • Suitable for biochemical and cell-based assays.
  • Supplied as a high-purity solid (~98.5%).
  • Molecular formula C21H27N7O3; molecular weight 425.48 g/mol.

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8

eMolecules​ (2-methyl-2H-indazol-7-yl)methanamine hydrochloride | 1400764-43-3 | MFCD22421660 | 1g

Pharmablock | (2-methyl-2H-indazol-7-yl)methanamine hydrochloride | 1g | 551066386 | PB02780-01 | | 1400764-43-3 | MFCD22421660 | 197.670 | C9H12ClN3

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