Azoles
Medchemexpress LLC Methyl Green zinc chloride | 7114-03-6 | 100 MG
Methyl Green zinc chloride is a potent fluorescent dye. It is used as a DNA stain for cells and electrophoretic gels, and can also be used for direct measuring of viability by both microscopy and flow cytometry, with peaks at 633 and 677 nm.
- Potent fluorescent dye.
- Stains DNA of cells and electrophoretic gels.
- Used for direct measuring of viability by microscopy.
- Used for direct measuring of viability by flow cytometry.
- Exhibits peaks at 633 and 677 nm.
Medchemexpress LLC Dimethyl methylene blue zinc chloride double salt | 931418-92-7 | MFCD19686959 | 99.6% | 416.04 | C18H22N3S·1/2ZnCl4 | 250mg
Dimethyl methylene blue zinc chloride double salt (DMMB) is a cationic dye Dimethyl methylene blue zinc chloride double salt competitively binds to the active site of the PANI-Benz-Ag nanocomposite with endotoxin releasing DMMB and increasing the fluorescence intensity Dimethyl methylene blue zinc chloride double salt can be used as a fluorescent probe for the detection of bacteria (such as E Coli) endotoxin[1]
Medchemexpress LLC 4-(Chloromethyl)-7-hydroxycoumarin | 25392-41-0 | 98.0% | C10H7ClO3 | 250 MG
4-(Chloromethyl)-7-hydroxycoumarin is a hydroxycoumarin derivative exhibiting potent antioxidant effects and high hydroxyl radical-scavenging properties. It contains a methyl group and a chlorine group within its heterocyclic ring. This compound has been investigated for its ability to inhibit the zinc enzyme carbonic anhydrase, particularly tumor-associated isoforms CA IX and XII.
- Exhibits potent antioxidant effect
- Possesses high hydroxyl radical-scavenging property
- Contains methyl and chlorine groups in the heterocyclic ring
- Investigated as an inhibitor of zinc enzyme carbonic anhydrase
- Targets tumor-associated isoforms CA IX and XII
- For research use only
Medchemexpress LLC 4-(Chloromethyl)-7-hydroxycoumarin | 25392-41-0 | 98.0% | C10H7ClO3 | 100 MG
4-(Chloromethyl)-7-hydroxycoumarin is a hydroxycoumarin derivative that exhibits potent antioxidant effects and high hydroxyl radical-scavenging properties. It contains a methyl group and a chlorine group within its heterocyclic ring. This compound has been investigated as a potent inhibitor of the zinc enzyme carbonic anhydrase, particularly the tumor-associated isoforms CA IX and XII.
- Exhibits potent antioxidant effects
- Possesses high hydroxyl radical-scavenging properties
- Contains a methyl group and a chlorine group in its heterocyclic ring
- Investigated as a potent inhibitor of zinc enzyme carbonic anhydrase
- Shows inhibitory activity against tumor-associated isoforms CA IX and XII
Medchemexpress LLC 4-(Chloromethyl)-7-hydroxycoumarin | 25392-41-0 | 98.01% | C10H7ClO3 | 1 ML
4-(Chloromethyl)-7-hydroxycoumarin is a hydroxycoumarin derivative exhibiting potent antioxidant effects and high hydroxyl radical-scavenging properties. It contains a methyl group and a chlorine group within its heterocyclic ring and has been investigated as a potent inhibitor of zinc enzyme carbonic anhydrase isoforms CA IX and XII.
- Potent antioxidant effect
- High hydroxyl radical-scavenging property
- Investigated as inhibitors of tumor-associated carbonic anhydrase isoforms CA IX and XII
Apexbio Technology LLC AGI-5198 1355326-35-0 25mg
AGI-5198 (CAS 1355326-35-0) is a selective inhibitor of mutant isocitrate dehydrogenase 1 (IDH1) harboring the R132H substitution Identified via high-throughput screening AGI-5198 blocks mutant IDH1-mediated formation of the oncometabolite R-2-hydroxyglutarate (R-2-HG) in a dose-dependent manner Mechanistically inhibition of mutant IDH1 by AGI-5198 induces expression of differentiation-associated zinc finger and BTB domain-containing protein 16 (ZBTB16 also termed PLZF) decreasing histone H3 lysine 9 trimethylation (H3K9me3) and promoting glioma cell differentiation In experimental glioma models AGI-5198 reduces tumor cell proliferation underscoring its utility for investigating differentiation therapy strategies targeting IDH1-mutant cancers