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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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Fluzoparib is a potent, orally active PARP1 inhibitor supplied for preclinical oncology research, used to study DNA damage repair and tumor responses in BRCA-mutant models.
Potent PARP1 inhibitor with low nanomolar enzymatic activity.
Orally active compound suitable for in vivo and in vitro studies.
Used to study DNA damage repair and BRCA1/2-mutant tumor responses.
Provided as a measured solid for precise dosing in preclinical experiments.
Molecular formula C22H16F4N6O2 and molecular weight 472.40 to support formulation and dosing calculations.
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FHT-1015 is a potent, selective small-molecule inhibitor of SMARCA4 and SMARCA2 ATPase activity, with low-nanomolar IC50 values. Supplied as a white to off-white solid and as a 10 mM solution in DMSO, the compound is intended for in vitro epigenetics and chromatin-remodeling research and includes manufacturer guidance for storage to maintain stability.
High potency against SMARCA4 and SMARCA2, IC50 ≈ 4-5 nM.
High chemical purity (>98%).
Available as solid and DMSO solution formats for experimental flexibility.
White to off-white solid appearance, suitable for analytical handling.
Storage recommendations provided for long- and short-term stability.
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NKY80 is a non-nucleoside quinazolinone inhibitor selective for adenylyl cyclase (AC) type V. It modulates AC catalytic activity in heart and lung tissues and exhibits IC50 values of 8.3 μM (AC V), 132 μM (AC III), and 1.7 mM (AC II). Supplied as a purified research compound for in vitro biochemical and pharmacological studies.
Selective adenylyl cyclase type V inhibitor (IC50 8.3 μM).
Non-nucleoside quinazolinone chemical class.
Approximately 99.8% purity.
Molecular weight 229.23 g·mol⁻1; formula C12H11N3O2.
Soluble in DMSO; intended for research use only.
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