Aminobenzoic acids and derivatives
Medchemexpress LLC CEP-28122 mesylate salt | 2070009-30-0 | 99.9% | 635.17 | 50 MG
CEP-28122 mesylate salt | 2070009-30-0 | 99.9% | 635.17 | 50 MG
Cayman Chemical WIN 55 212 mesylate
A racemic mixture of (+)-WIN 55,212-2 and (−)-WIN 55,212-3; inhibits electrically induced contractions in mouse vas deferens preparations (IC50 = 0.006 µM) and reduces PG synthesis by 35% in mouse brain microsomes at 30 µM; decreases acetylcholine-induced writhing in mice (ED50 = 0.25 mg/kg); induces hypolocomotion, analgesia, hypothermia, and catalepsy in mice (ED50s = 1.09, 0.5, 3.01 and 6.8 mg/kg, respectively)
Selleck Chemical LLC Dolasetron Mesylate
Dolasetron Mesylate (Anzemet hydrate MDL-73147EF) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy
Apexbio Technology LLC KB-R7943 mesylate 182004-65-5 10mg
KB-R7943 mesylate (CAS 182004-65-5) is a selective inhibitor of the Na /Ca2 exchanger (NCX) particularly effective against its reverse mode It inhibits NCX-mediated Ca2 influx with an IC50 of 0 7 M In transfected Chinese hamster ovary (CHO) cells expressing NCX KB-R7943 suppresses exchanger activity at high intracellular Na concentrations In cultured rat forebrain neurons it attenuates Ca2 transients induced by glutamate NMDA kainate or KCl with IC50 values ranging from 2 9 to 8 2 M In in vivo studies KB-R7943 reduces endothelin-1 levels and mitigates acute renal dysfunction following ischemic injury This compound is widely utilized in studies investigating Na /Ca2 exchange and related calcium signaling pathways
TARGETMOL CHEMICALS INC BIIB 722 Mesylate 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. BIIB 722 Mesylate is a selective sodium-hydrogen exchange inhibitor with cardioprotective properties and can be used to study myocardial ischemia and myocardial infarction. Purity 99.49%
Selleck Chemical LLC Benztropine mesylate S3163-1g
Benztropine(Cogentin mesylate Benztropine methanesulfonate) is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM
Medchemexpress LLC Enasidenib mesylate | 1650550-25-6 | 99.7% | 569.48 | 5 MG
Enasidenib mesylate is a first-in-class, oral, potent, reversible, and selective inhibitor of the IDH2 mutant enzymes. It reverses the effects of mutant IDH2 on DNA methylation in mutant stem/progenitor cells, inducing differentiation and impairing self-renewal of IDH2-mutant leukemia cells. In vivo studies demonstrate that treatment with enasidenib significantly improves survival in an IDH2-mutant acute myeloid leukemia (AML) primary xenograft mouse model by remodeling the epigenetic state and reducing 2-hydroxyglutarate (2-HG) levels, consistent with on-target inhibition.
- Novel approach to treatment
- Convenient oral administration
- Potent, reversible, and selective inhibitor
- Induces differentiation of leukemic cells
- Improves survival in AML models
- Effectively reduces 2-hydroxyglutarate
- Remodels epigenetic state of IDH2-mutant cells
Medchemexpress LLC Bifeprunox mesylate | 350992-13-1 | MFCD09840052 | 99.9% | 481.56 | C25H27N3O5S | 5 MG
Bifeprunox mesylate is a research chemical that functions as a dopamine D2-like and 5-HT1A receptor partial agonist. Supplied as the mesylate salt for laboratory use, it is intended for preclinical in vitro and in vivo studies and is not for human or clinical application.
- Acts as a dopamine D2-like and 5-HT1A receptor partial agonist.
- Provided as the mesylate salt (solid form).
- High reported purity (about 99.9% by HPLC).
- Suitable for in vitro and in vivo preclinical research.
- Available in small research pack sizes, such as 5 mg.
- Molecular weight approximately 481.56 g/mol.
![Medchemexpress LLC 4(5h)-thiazolone, 2-amino-5-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]-, (5z)- | 139340-56-0 | MFCD00906463 | 99.7% | 428.57 g·mol⁻¹ | C19H28N2O5S2 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000249146.png-250.jpg)
Medchemexpress LLC 4(5h)-thiazolone, 2-amino-5-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]-, (5z)- | 139340-56-0 | MFCD00906463 | 99.7% | 428.57 g·mol⁻¹ | C19H28N2O5S2 | 1 ML
Darbufelone mesylate is a research-grade small-molecule inhibitor that dual inhibits cellular PGF2α and LTB4 production and potently inhibits PGHS-2 (IC50 = 0.19 μM). Supplied as a solid and as a pre-made solution in DMSO, it is intended for research use only.
- Dual inhibition of PGF2α and LTB4 production.
- Potent PGHS-2 inhibitor (IC50 = 0.19 μM).
- Available as a solid and as a 10 mM solution in DMSO.
- High purity (99.65%).
- Soluble in DMSO (110 mg/mL); insoluble in water.
- Storage: solid at 4°C; in solvent -80°C (6 months) or -20°C (1 month).
- For research use only; not for human or clinical use.
Medchemexpress LLC Pefloxacin mesylate | 70458-95-6 | 99.7% | 1 ML
Pefloxacin mesylate | 70458-95-6 | 99.7% | 1 ML
Apexbio Technology LLC Pergolide mesylate 66104-23-2 25mg
Pergolide mesylate is a small-molecule agonist targeting dopamine D2-family receptors It is designed to activate these receptors thereby modulating dopaminergic pathways in the central nervous system Pergolide mesylate exerts its biological activity primarily through agonism of dopamine receptors Based on these pharmacological properties pergolide mesylate holds research potential in studies of dopaminergic neurotransmission receptor signaling pathways Parkinson s disease mechanisms and the investigation of therapeutic mechanisms for neurodegenerative disorders characterized by dopaminergic deficits
Medchemexpress LLC NSC243928 (mesylate) | 59988-01-1 | 99.3% | 503.59 g/mol | C23H25N3O6S2 | 10MG
NSC243928 mesylate is a small-molecule binder of lymphocyte antigen 6 (LY6) that inhibits cell growth and exhibits anticancer activity. The compound is provided as the mesylate salt, with a reported high purity and defined molecular formula and weight, and is intended for research use under controlled laboratory conditions.
- Small-molecule LY6 binder with reported anticancer activity.
- Inhibits cell growth in relevant assays.
- High reported purity (approximately 99.3%).
- Molecular formula C23H25N3O6S2 and molecular weight 503.59 g/mol.
- Soluble in DMSO at about 10 mg/mL (may require warming or sonication).
- Stable as a sealed powder when stored at 4°C and protected from moisture.
eMolecules ChemScene Exatecan (mesylate) 1g 602866165 CS-2952 169869-90-3 MFCD04113012 531.560 C25H26FN3O7S
ChemScene Exatecan (mesylate) 1g 602866165 CS-2952 169869-90-3 MFCD04113012 531.560 C25H26FN3O7S
Medchemexpress LLC 1H-inden-1-amine, 2,3-dihydro-N-2-propyn-1-yl-, (1R)-, methanesulfonate (1:1) | 161735-79-1 | 99.8% | C13H17NO3S | 10MG
Rasagiline mesylate is the mesylate salt of rasagiline, a selective, irreversible monoamine oxidase B (MAO-B) inhibitor supplied for research and analytical use. The product is provided in solid and solution forms and is suitable as an analytical standard and biochemical assay reagent.
- High purity: 99.8%.
- CAS number 161735-79-1 confirmed.
- Molecular formula C13H17NO3S; molecular weight 267.34 g/mol.
- Available as solid and as a 10 mM solution in water.
- Intended for research and analytical applications.
TARGETMOL CHEMICALS INC Masupirdine mesylate 10MG
Also available in 1 mL, 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Masupirdine mesylate (SUVN-502 mesylate) is a selective 5-HT6 receptor antagonist that crosses the blood-brain barrier and is utilized in the study of neurological disorders such as Alzheimer's disease and dementia. Purity 99.48%