Anilides
Aobchem 2-Bromo-7-(phenylmethoxy)naphthalene | 97% | CAS 1374750-65-8 | C17H13BrO | 5g
2-Bromo-7-(phenylmethoxy)naphthalene | 97% | CAS 1374750-65-8 | C17H13BrO | 5g
Aobchem 1-[(4-Bromophenyl)methoxy]naphthalene | 97% | CAS 884163-01-3 | C17H13BrO | 5g
1-[(4-Bromophenyl)methoxy]naphthalene | 97% | CAS 884163-01-3 | C17H13BrO | 5g
Aobchem 1-Bromo-4-(difluoromethoxy)naphthalene | ≥97% | CAS 1261783-62-3 | C11H7BrF2O | 1g
1-Bromo-4-(difluoromethoxy)naphthalene | ≥97% | CAS 1261783-62-3 | C11H7BrF2O | 1g
Aobchem 1-Bromo-4-(difluoromethoxy)naphthalene | ≥97% | CAS 1261783-62-3 | C11H7BrF2O | 250mg
1-Bromo-4-(difluoromethoxy)naphthalene | ≥97% | CAS 1261783-62-3 | C11H7BrF2O | 250mg
Aobchem 1-Bromo-4-(difluoromethoxy)naphthalene | ≥97% | CAS 1261783-62-3 | C11H7BrF2O | 500mg
1-Bromo-4-(difluoromethoxy)naphthalene | ≥97% | CAS 1261783-62-3 | C11H7BrF2O | 500mg
Aobchem 1-Bromo-4-(methoxymethyl)naphthalene | 97% | CAS 136053-64-0 | C12H11BrO | 1g
1-Bromo-4-(methoxymethyl)naphthalene | 97% | CAS 136053-64-0 | C12H11BrO | 1g
Aobchem N N-Bis(1-methylethyl)-2-naphthalenecarboxamide | ≥95% | CAS 31609-22-0 | C17H21NO | 1g
N N-Bis(1-methylethyl)-2-naphthalenecarboxamide | ≥95% | CAS 31609-22-0 | C17H21NO | 1g
Medchemexpress LLC Leflunomide | 75706-12-6 | C12H9F3N2O2 | 500 MG
Leflunomide is a pyrimidine synthesis inhibitor, primarily functioning by inhibiting dihydroorotate dehydrogenase (DHODH), and is recognized as a disease-modifying antirheumatic agent. This prodrug inhibits the proliferation of mononuclear and T-cells and acts as an inhibitor of several protein tyrosine kinases, with IC50 values ranging from 30 mM to 100 mM in in vitro assays. It also interferes with cell cycle progression and utilizes p53-dependent mechanisms to prevent the expansion of activated and autoimmune lymphocytes.
- Inhibits dihydroorotate dehydrogenase (DHODH)
- Acts as a disease-modifying antirheumatic agent
- Inhibits proliferation of mononuclear and T-cells
- Functions as an inhibitor of several protein tyrosine kinases
- Inhibits p59fyn and p56lck activity in tyrosine kinase assays
- Inhibits calcium mobilization in Jurkat cells
- Prevents expansion of activated and autoimmune lymphocytes
Selleck Chemical LLC Leflunomide S1247-10mM/1mL
Leflunomide is a pyrimidine synthesis and protein tyrosine kinase inhibitor belonging to the DMARD used as an immunosuppressant agent The active metabolite of Leflunomide is A77 1726 which inhibits dihydroorotate dehydrogenase (DHODH) Leflunomide is also an agonist of the AhR
Apexbio Technology LLC S-Nitroso-N-acetyl-DL-penicillamine 67776-06-1 50mg
S-Nitroso-N-acetyl-DL-penicillamine (SNAP CAS 67776-06-1) is a low-molecular-weight nitric oxide (NO) donor that facilitates the sustained release of NO in biological systems By elevating NO levels SNAP stimulates soluble guanylate cyclase activity resulting in increased cyclic guanosine monophosphate (cGMP) production and subsequent modulation of downstream signaling pathways These actions contribute to vascular smooth muscle relaxation and vasodilation SNAP is widely employed in experimental studies to investigate NO-mediated mechanisms including inhibition of platelet aggregation and regulation of inflammatory responses and serves as a valuable reagent for probing NO signaling in cultured cells
Medchemexpress LLC Boscalid | 188425-85-6 | 99.8% | 1 G
Boscalid is a fungicidal research chemical that inhibits succinate dehydrogenase (SDH), disrupting fungal respiration. It is supplied for research and analytical applications and is available as a solid or as a 10 mM solution in DMSO.
- Provides fungicidal activity as a succinate dehydrogenase inhibitor
- High purity suitable for analytical use (99.8%)
- Molecular formula C18H12Cl2N2O; molecular weight 343.21 g/mol
- Available in solid form and as a 10 mM solution in DMSO; common pack sizes include 50 mg-1 g
- Intended for research use only; not for human or veterinary use
Medchemexpress LLC Animal-free NAP-2/CXCL7 protein, human (His) | >95.0% | 2UG
Recombinant human NAP-2/CXCL7 protein fragment with an N-terminal 6xHis tag, produced in E. coli and supplied with a certificate of analysis. The preparation corresponds to residues A59-D128 (70 amino acids), has an approximate molecular weight of ~11 kDa, and is ≥95.0% pure by reducing SDS-PAGE. For research use only.
- Recombinant fragment representing residues A59-D128.
- N-terminal 6xHis tag for purification and detection.
- Produced in E. coli for efficient expression.
- Purity ≥95.0% as determined by reducing SDS-PAGE.
- Provided with a certificate of analysis for batch-specific data.
- Suitable for biochemical assays and antibody development.
Apexbio Technology LLC Leflunomide 75706-12-6 10mM (in 1mL DMSO)
Leflunomide (CAS 75706-12-6) is a small-molecule agonist targeting the aryl hydrocarbon receptor (AHR) pathway It is designed to modulate AHR signaling thereby enhancing regulatory T cell (Treg) numbers altering inflammatory cytokine profiles and influencing immune responses Leflunomide exerts its biological activity primarily through metabolic conversion to its active metabolite Teriflunomide (A771726) which mediates immunosuppressive effects It enhances IL-10 production and suppresses IL-17 and IL-23 secretion In cell-based studies leflunomide demonstrates anti-proliferative efficacy in human medullary thyroid carcinoma cells (MTC-TT) with IC50 values ranging from approximately 30 to 50 M depending on specific assay conditions Based on these pharmacological properties leflunomide holds research potential in ischemia-reperfusion renal injury sepsis-induced intestinal oxidative stress and tumor proliferation inhibition models
Medchemexpress LLC 4-hydroxyphenyl diphenyl phosphate | 56806-74-7 | MFCD30529787 | 95.0% | 342.28 g/mol | C18H15O5P | 5 MG
4-Hydroxyphenyl diphenyl phosphate is a hydroxylated metabolite of organophosphate flame retardants commonly used as a research reagent in environmental, toxicological, and analytical studies. The compound has formula C18H15O5P and a molecular weight of 342.28 g/mol. Suppliers commonly offer mg-scale packs for laboratory use; consult the certificate of analysis for lot-specific purity and storage conditions.
- Hydroxylated metabolite of organophosphate flame retardants.
- Suitable for environmental and toxicological studies.
- Provided in small, research-oriented pack sizes (mg scale).
- Formula C18H15O5P and molecular weight 342.28 g/mol.
- Certificate of Analysis available for lot-specific purity and storage.
Aobchem 1-Bromo-4-(3-fluorophenyl)naphthalene | 97% | CAS 2918962-20-4 | C16H10BrF | 250mg
1-Bromo-4-(3-fluorophenyl)naphthalene | 97% | CAS 2918962-20-4 | C16H10BrF | 250mg