Benzenesulfonamides
Medchemexpress LLC Furosemide (Standard) | 54-31-9 | 99.9% | 25 MG
Furosemide (Standard) is an analytical standard of Furosemide with a purity of 99.95%. It is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, specifically NKCC1 and NKCC2, and also acts as a GABAA receptor antagonist. This compound functions as a loop diuretic and is used in the study of congestive heart failure, hypertension, and edema, serving as a reference for qualitative, quantitative, and methodological research experiments.
- Intended for research and analytical applications
- Potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter
- Acts as a GABAA receptor antagonist
- Functions as a loop diuretic
- Used in the study of congestive heart failure, hypertension, and edema
- Analytical standard for qualitative, quantitative, and methodological research experiments
Medchemexpress LLC HY-15868 50mg , HS-173 CAS:1276110-06-5 Purity:98%
Medchemexpress, HY-15868 50mg HS-173 CAS:1276110-06-5 Formula:C21H18N4O4S IC50: 0.8 nM (PI3Kα) Purity:98% HS-173 is a novel PI3K inhibitor, that is used for cancer treatment. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 871329-74-7 | 2-Methyl-5-(N-morpholinylsulfonyl)phenylboronic acid | Combi-Blocks | MFCD07363761 | 285.120 | C11H16BNO5S | 98.000 | Cc1ccc(cc1B(O)O)S(=O)(=O)N1CCOCC1 | 1g | 117521514
2-Methyl-5-(N-morpholinylsulfonyl)phenylboronic acid | Combi-Blocks | 871329-74-7 | MFCD07363761 | 285.120 | C11H16BNO5S | 98.000 | Cc1ccc(cc1B(O)O)S(=O)(=O)N1CCOCC1 | 1g | 117521514
![eMolecules 99-54-7 | 1,2-Dichloro-4-nitrobenzene | Oakwood Chemical | MFCD00007207 | 192.000 | C6H3Cl2NO2 | 98.000 | [O-][N+](=O)c1ccc(Cl)c(Cl)c1 | 25g | 537717111](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502148816.JPG-250.jpg)
eMolecules 99-54-7 | 1,2-Dichloro-4-nitrobenzene | Oakwood Chemical | MFCD00007207 | 192.000 | C6H3Cl2NO2 | 98.000 | [O-][N+](=O)c1ccc(Cl)c(Cl)c1 | 25g | 537717111
1,2-Dichloro-4-nitrobenzene | Oakwood Chemical | 99-54-7 | MFCD00007207 | 192.000 | C6H3Cl2NO2 | 98.000 | [O-][N+](=O)c1ccc(Cl)c(Cl)c1 | 25g | 537717111
Medchemexpress LLC Navitoclax-piperazine | 2143096-93-7 | MFCD32693949 | 99.7% | 973.63 | C47H56ClF3N6O5S3 | 10 MG
Navitoclax-piperazine is a research chemical and analog of navitoclax that functions as a BCL-XL inhibitor, supplied as a white to off-white solid for biochemical and cell-based studies. It is typically provided in small milligram quantities and is characterized by high purity and a large molecular weight.
- BCL-XL inhibitor useful for apoptosis and oncology research.
- High purity (~99.7%) suitable for research applications.
- Supplied as a white to off-white solid for ease of handling.
- Available in small milligram quantities and as 10 mM solutions in DMSO for ready use.
- Molecular formula C47H56ClF3N6O5S3; molecular weight 973.63.
eMolecules 1001415-32-2 | 1-(benzenesulfonyl)-4-bromo-1H-indazole | Pharmablock | MFCD22566216 | 337.190 | C13H9BrN2O2S | 97.000 | Brc1cccc2n(ncc12)S(=O)(=O)c1ccccc1 | 1g | 551134017
1-(benzenesulfonyl)-4-bromo-1H-indazole | Pharmablock | 1001415-32-2 | MFCD22566216 | 337.190 | C13H9BrN2O2S | 97.000 | Brc1cccc2n(ncc12)S(=O)(=O)c1ccccc1 | 1g | 551134017
eMolecules 1899-94-1 | 3-Methylbenzenesulfonamide | Oakwood Chemicals | MFCD04066695 | 171.210 | C7H9NO2S | 98.000 | Cc1cccc(c1)S(N)(=O)=O | 25g | 480123629
3-Methylbenzenesulfonamide | Oakwood Chemicals | 1899-94-1 | MFCD04066695 | 171.210 | C7H9NO2S | 98.000 | Cc1cccc(c1)S(N)(=O)=O | 25g | 480123629
Medchemexpress LLC Sildenafil chlorosul 1g
Sildenafil chlorosulfonyl is a synthetic intermediate in the synthesis of the phosphodiesterase 5 (PDE5) inhibitor Sildenafil (HY-15025)
Apexbio Technology LLC Bosentan Hydrate 157212-55-0 100mg
Bosentan Hydrate (CAS 157212-55-0) is a sulfonamide-derived competitive antagonist of endothelin receptors exhibiting preferential affinity toward endothelin A over endothelin B receptors By interfering with endothelin-triggered signaling in endothelial and vascular smooth muscle cells it attenuates vasoconstrictive and bronchoconstrictive responses In vitro studies revealed bosentan inhibited endothelin receptor activity in P388/dx cells (IC50 15 1 1 6 M) and effectively reversed antiangiogenic effects of systemic sclerosis patient sera on dermal microvascular endothelial cells In animal models bosentan administration post-myocardial infarction significantly elevated plasma leptin levels Clinically bosentan is applied extensively in research on pulmonary arterial hypertension showing beneficial outcomes on patients exercise capacity
Apexbio Technology LLC Glibenclamide 10238-21-8 10mM (in 1mL DMSO)
Glibenclamide (CAS 10238-21-8) is a sulfonylurea-class small molecule widely utilized in biomedical research for its ability to modulate insulin release It acts primarily by binding to ATP-sensitive potassium channels (K ATP channels) in pancreatic beta cells This interaction results in channel closure leading to cellular depolarization calcium ion influx and subsequent insulin secretion Due to its well-characterized mechanism glibenclamide is particularly relevant in diabetes-related research focusing on insulin regulation and beta-cell physiology
eMolecules 173529-46-9 | (E)-4-(2-(N-((4-Methoxyphenyl)sulfonyl)acetamido)styryl)pyridine 1-oxide | MFCD12756255 | 100mg
Ambeed | 2-Bromo-5-iodobenzoic acid | 10g | 552641323 | A201001 | 25252-00-0 | MFCD00079716 | 326.915 | C7H4BrIO2
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Apexbio Technology LLC Bosentan Hydrate 157212-55-0 200mg
Bosentan Hydrate (CAS 157212-55-0) is a sulfonamide-derived competitive antagonist of endothelin receptors exhibiting preferential affinity toward endothelin A over endothelin B receptors By interfering with endothelin-triggered signaling in endothelial and vascular smooth muscle cells it attenuates vasoconstrictive and bronchoconstrictive responses In vitro studies revealed bosentan inhibited endothelin receptor activity in P388/dx cells (IC50 15 1 1 6 M) and effectively reversed antiangiogenic effects of systemic sclerosis patient sera on dermal microvascular endothelial cells In animal models bosentan administration post-myocardial infarction significantly elevated plasma leptin levels Clinically bosentan is applied extensively in research on pulmonary arterial hypertension showing beneficial outcomes on patients exercise capacity