Benzenesulfonamides
![eMolecules 171599-83-0 | Sildenafil (citrate) | Medchem Express | MFCD09026931 | 666.700 | C28H38N6O11S | 98.000 | OC(=O)CC(O)(CC(O)=O)C(O)=O.CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 | 50mg | 446264915](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000193304.jpg-250.jpg)
eMolecules 171599-83-0 | Sildenafil (citrate) | Medchem Express | MFCD09026931 | 666.700 | C28H38N6O11S | 98.000 | OC(=O)CC(O)(CC(O)=O)C(O)=O.CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 | 50mg | 446264915
Sildenafil (citrate) | Medchem Express | 171599-83-0 | MFCD09026931 | 666.700 | C28H38N6O11S | 98.000 | OC(=O)CC(O)(CC(O)=O)C(O)=O.CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 | 50mg | 446264915
Frontier Specialty Chemicals 1G 4-BROMO-N,N-DIMETHYLBENZENE
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4-Bromo-N,N-dimethylbenzenesulfonamide; CAS No: 707-60-8
![Medchemexpress LLC 4-[[4-(2-butynyloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-(3S)thiomorpholinecarboxamide | 287403-39-8 | 99.6% | 398.50 | C17H22N2O5S2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000248189.png-250.jpg)
Medchemexpress LLC 4-[[4-(2-butynyloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-(3S)thiomorpholinecarboxamide | 287403-39-8 | 99.6% | 398.50 | C17H22N2O5S2 | 10 MG
TMI-1 is a small-molecule inhibitor of TNF-α converting enzyme (TACE/ADAM17) with activity against several ADAM and matrix metalloproteinase (MMP) family proteases. It has demonstrated antiproliferative and pro-apoptotic effects in cancer cell models and can suppress TNF-α secretion and inflammatory responses in preclinical studies. Supplied as a high-purity solid for research use.
- Inhibits TACE (ADAM17) and multiple MMPs with low-nanomolar potency.
- Demonstrates antiproliferative and apoptosis-inducing activity in cellular models.
- Reduces TNF-α secretion and inflammatory markers in preclinical studies.
- High purity solid suitable for biochemical and cellular assays.
- Available in small mass packs for research applications.
![eMolecules 1014613-05-8 | 1-(benzenesulfonyl)-4-bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine | MFCD13191645 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502136296.JPG-250.jpg)
eMolecules 1014613-05-8 | 1-(benzenesulfonyl)-4-bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine | MFCD13191645 | 1g
ChemScene | 135-Triethylbenzene | 1g | 694122597 | CS-0046776 | 102-25-0 | MFCD00009261 | 162.276 | C12H18
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eMolecules Building Block Tool
Accela Chembio Inc 4-ethylbenzenesulfonamide | 100g | 138-38-5 | MFCD01365828 | 97+% | Shelf Life: 1260 Days | Light Sensitive
4-ethylbenzenesulfonamide | 100g | 138-38-5 | MFCD01365828 | 97+% | Shelf Life: 1260 Days | Light Sensitive
Medchemexpress LLC Sulfacetamide sodium monohydrate | 6209-17-2 | 99.8% | 100 G
Sulfacetamide sodium monohydrate is a sulfonamide antibiotic primarily used for research purposes. It demonstrates both antibacterial and antifungal activities, making it suitable for the study of various ocular infections.
- Can be used for the study of various ocular infections, including trachoma, blepharitis, conjunctivitis, corneal ulcer, pityriasis versicolor, and rosacea.
- Exhibits antifungal activity.
- Acts as a bacteriostatic agent against Gram-positive and Gram-negative bacteria.
- For research use only.
Accela Chembio Inc 4-fluoro-3-nitrobenzenesulfonamide | 5g | 406233-31-6 | MFCD08703185 | 97+% | Shelf Life: 1260 Days | Regular
4-fluoro-3-nitrobenzenesulfonamide | 5g | 406233-31-6 | MFCD08703185 | 97+% | Shelf Life: 1260 Days | Regular
Medchemexpress LLC N-desmethyl sildenafil | 139755-82-1 | MFCD00908398 | 99.5% | 460.55 | C21H28N6O4S | 25 MG
N-desmethyl sildenafil is the primary N-desmethylated metabolite of sildenafil supplied as an analytical reference standard for laboratory research. It is available in solid and solution formats for analytical applications and quality control, and is intended for research use only (not for human or clinical use).
- Provided as solid and solution formats for flexibility in assays.
- High purity (99.5%) suitable for analytical and reference standard use.
- Molecular formula C21H28N6O4S; molecular weight 460.55.
- Used in pharmacokinetic, metabolite identification, and analytical method development studies.
- Available in multiple small-scale pack sizes for laboratory workflows.
Medchemexpress LLC HY-112438 5mg Medchemexpress, MF-094 CAS:2241025-68-1 Purity:>98%
Medchemexpress, HY-112438 5mg MF-094 CAS:2241025-68-1 MF-094 is a potent and selective USP30 inhibitor with an IC 50 of 120 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical Sildenafil Inhibitors
A PDE5 inhibitor (IC50s = 3.6 and 3 nM for PDE5 activity in isolated rabbit platelets and human corpus cavernosum, respectively); selective for PDE5 over PDE1 and PDE3 (IC50s = 0.26 and 65 μM, respectively); reverses glucose-induced decreases in ANG1 expression and reduction of capillary-like tube formation by mouse dermal endothelial cells in vitro; increases the number of functional blood vessels and regional blood flow in the sciatic nerve in a db/db mouse model of diabetic peripheral neuropathy; increases ICP/MAP ratio in castrated rats at 20 mg/kg per day; reduces cardiac arrest and resuscitation-induced increases in angiotensin II ACE, ACE2, and various angiotensin receptors and increases survival in a porcine model of ischemia/reperfusion injury
eMolecules 97-04-1 | ChemScene | 2-Chloro-5-sulfamoylbenzoic acid | 100mg | 761228608 | CS-0462903 | MFCD00036103 | 235.64 | C7H6ClNO4S
ChemScene | 2-Chloro-5-sulfamoylbenzoic acid | 100mg | 761228608 | CS-0462903 | 97-04-1 | MFCD00036103 | 235.640 | C7H6ClNO4S
AdipoGen Glimepiride (1 g)
Chemical. CAS: 93479-97-1. Formula: C24H34N4O5S. MW: 490.62. Glimepiride is a long-acting sulfonylurea antidiabetic agent inhibiting ATP-sensitive potassium (KATP) channels in pancreatic beta-cells, which leads to the release of insulin. In addition, Glimepiride increases the activity of intracellular insulin receptors. Studies conducted on adipocytes and skeletal muscle suggest that Glimepiride induces the PI3 kinase (PI3K) and Akt pathway, along with insulin receptor substrate-1/2 and endothelial nitric oxide synthase and stimulates glucose transporter 1 and 4 (GLUT1/4) expression. Glimepiride also increases osteoblast proliferation and differentiation, which is thought to be related to its ability to activate the PI3K and Akt pathway and exhibits neuroprotective benefit, decreasing expression and activity of BACE1 and amyloid-beta (Abeta) in neurons in a PPARgamma-dependent manner.
Frontier Specialty Chemicals 5G 4-BROMO-N,N-DIMETHYLBENZENE
4-Bromo-N,N-dimethylbenzenesulfonamide; CAS No: 707-60-8
Medchemexpress LLC HY-16586 10mg Medchemexpress, PFI-1 CAS:1403764-72-6 Purity:>98%
Medchemexpress, HY-16586 10mg PFI-1 CAS:1403764-72-6 PFI-1 is a selective BET (bromodomain-containing protein) inhibitor for BRD4 with IC50 of 0.22 μM in a cell-free assay. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.