Benzenesulfonamides
Apexbio Technology LLC Sulfasalazine 599-79-1 10mM (in 1mL DMSO)
Sulfasalazine (599-79-1) is a small-molecule inhibitor targeting the NF- B signaling pathway and the cystine-glutamate antiporter system (system Xc-) It is designed to suppress NF- B activation and inhibit cystine uptake thereby modulating inflammatory gene expression and intracellular glutathione synthesis Sulfasalazine exerts its biological activity primarily through inhibition of NF- B activation and blockade of system Xc- In in vitro studies sulfasalazine demonstrates growth inhibition and induction of apoptosis in several cancer cell lines including MIA PaCa-2 PANC-1 and glioblastoma cells with reported IC50 values ranging from approximately 0 2 to 0 5 mM depending on cell type and conditions Based on these pharmacological properties sulfasalazine holds research potential in inflammation NF- B signaling oxidative stress modulation and cancer studies
Apexbio Technology LLC Glibenclamide 10238-21-8 10mM (in 1mL DMSO)
Glibenclamide (CAS 10238-21-8) is a sulfonylurea-class small molecule widely utilized in biomedical research for its ability to modulate insulin release It acts primarily by binding to ATP-sensitive potassium channels (K ATP channels) in pancreatic beta cells This interaction results in channel closure leading to cellular depolarization calcium ion influx and subsequent insulin secretion Due to its well-characterized mechanism glibenclamide is particularly relevant in diabetes-related research focusing on insulin regulation and beta-cell physiology
Medchemexpress LLC HY-10087 10mg Medchemexpress, Navitoclax CAS:923564-51-6 Purity:>98%
Medchemexpress, HY-10087 10mg Navitoclax CAS:923564-51-6 Navitoclax (ABT-263) is a potent and orally active Bcl-2 family protein inhibitor that binds to multiple anti-apoptotic Bcl-2 family proteins, such as Bcl-x L , Bcl-2 and Bcl-w, with a K i of less than 1 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 1349796-36-6 | XL765 Analogue | MFCD18252649 | 50mg
Medchem Express | 680C91 | 5mg | 721309296 | HY-108681 | 163239-22-3 | MFCD20926361 | 238.265 | C15H11FN2
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Cayman Chemical GlImepIrIde 500mg
An inhibitor of SUR1/Kir6.2, SUR2A/Kir6.2, and SUR2B/Kir6.2 (IC50s = 3, 5.4, and 7.3 nM, respectively, in Xenopus oocytes expressing the mouse receptor); induces InsR complex dissociation and insulin degradation in HepG2 cells at 20 µM; decreases blood glucose and plasma insulin levels in a KKAy mouse model of insulin-resistant type 2 diabetes at 0.05 mg/kg per day; reduces HbA1c levels in the same model at 0.5 mg/kg per day
eMolecules 957060-91-2 | 4-(N-(4-Methoxybenzyl)sulfamoyl)phenylboronic acid | Combi-Blocks | MFCD09027228 | 321.150 | C14H16BNO5S | 98.000 | COc1ccc(CNS(=O)(=O)c2ccc(cc2)B(O)O)cc1 | 1g | 117522926
4-(N-(4-Methoxybenzyl)sulfamoyl)phenylboronic acid | Combi-Blocks | 957060-91-2 | MFCD09027228 | 321.150 | C14H16BNO5S | 98.000 | COc1ccc(CNS(=O)(=O)c2ccc(cc2)B(O)O)cc1 | 1g | 117522926
eMolecules 80360-14-1 | 3-IODO-1-(PHENYLSULFONYL)INDOLE | AstaTech | MFCD09037474 | 383.200 | C14H10INO2S | 95.000 | Ic1cn(c2ccccc12)S(=O)(=O)c1ccccc1 | 0.25g | 798867064
3-IODO-1-(PHENYLSULFONYL)INDOLE | AstaTech | 80360-14-1 | MFCD09037474 | 383.200 | C14H10INO2S | 95.000 | Ic1cn(c2ccccc12)S(=O)(=O)c1ccccc1 | 0.25g | 798867064
Cayman Chemical SIldenafIl-d3 500ug
An internal standard for the quantification of sildenafil by GC- or LC-MS
eMolecules 139755-85-4 | Medchem Express | Lodenafil | 5mg | 475641600 | HY-123210 | MFCD27977991 | 504.61 | C23H32N6O5S
ChemScene | 5-Bromo-1234-tetrahydronaphthalen-1-amine hydrochloride | 100mg | 569145797 | CS-0101657 | 1810070-15-5 | MFCD28986156 | 262.580 | C10H13BrClN
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Medchemexpress LLC N-Benzyl-N-Cbz-glycine | 76315-01-0 | 265.31 | 500 MG
2-(Benzyl(tert-butoxycarbonyl)amino)acetic acid is a Glycine derivative. Amino acids and amino acid derivatives are commercially used as ergogenic supplements, influencing anabolic hormone secretion, fuel supply during exercise, mental performance during stress-related tasks, and preventing exercise-induced muscle damage. They are recognized as beneficial ergogenic dietary substances.
- Glycine derivative
- Used as ergogenic supplements
- Influences anabolic hormone secretion
- Influences fuel supply during exercise
- Influences mental performance during stress-related tasks
- Prevents exercise-induced muscle damage
- Recognized as beneficial ergogenic dietary substances
Medchemexpress LLC 7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene | 84030-20-6 | MFCD00043004 | 98.0% | C8H15N3 | 100 G
7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene is a chemical compound. This product has a high purity of 98.0% and is identified by its CAS number 84030-20-6 and MFCD number MFCD00043004. Its chemical formula is C8H15N3.
- High purity for reliable research
- Unique chemical structure for specialized applications
- Identified by standard chemical identifiers (CAS, MFCD)
Apexbio Technology LLC RN 1734 946387-07-1 10mg
RN 1734 (CAS 946387-07-1) is a selective antagonist of the TRPV4 ion channel demonstrated to inhibit 4 PDD-induced TRPV4 activation It exhibits low micromolar IC50 values against human (2 3 M) rat (5 9 M) and mouse (3 2 M) TRPV4 indicating high potency across species In experimental models RN 1734 decreases the production of inflammatory cytokines TNF- and IL-1 without affecting the number of oligodendrocyte lineage markers Due to these properties RN 1734 is widely utilized in studies investigating TRPV4 function and the role of this channel in inflammation-related pathologies
Medchemexpress LLC HY-B0442A 100mg Medchemexpress, Vardenafil (hydrochloride) CAS:224785-91-5 Purity:>98%
Medchemexpress, HY-B0442A 100mg Vardenafil (hydrochloride) CAS:224785-91-5 Vardenafil hydrochloride is a selective, orally active, potent inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil hydrochloride shows selectivity over PDE1 (180 nM), PDE6 (11 nM), PDE2, PDE3, and PDE4 (>1000 nM). Vardenafil hydrochloride competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Vardenafil hydrochloride can be used for the research of erectile dysfunction. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC S-configured azido peg-linked naphthyl propanoic acid trifluoroacetate | 2320477-41-4 | 899.91 | C43H52F3N7O11 | 5mg
(S)-3-(4-(4-((14-Azido-3 6 9 12-tetraoxatetradecyl)oxy)naphthalen-1-yl)phenyl)-3-(2-(4-((4-methylpyridin-2-yl)amino)butanamido)acetamido)propanoic acid compound trifluoroacetate is a drug intermediate for synthesis of various active compounds