Benzenesulfonic acids and derivatives
Sigma Aldrich Fine Chemicals Biosciences alpha Ketoglutaric acid po1KG
alpha Ketoglutaric acid po1KG
Medchemexpress LLC Setmelanotide (monoacetate) | 2759937-80-7 | 99.8% | 1177.36 | 25 MG
Setmelanotide (monoacetate) is a melanocortin 4 receptor (MC4R) agonist. It acts on human and rat MC4R with EC50 values of 0.27 nM and 0.28 nM, respectively, and is intended for research use only.
- Acts on human and rat MC4R
- Stable as a solid
- Suitable for research use
Medchemexpress LLC Disodium monofluorophosphate | 10163-15-2 | 50 G
Disodium monofluorophosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is intended for research use only.
- Used as a biochemical reagent
- Suitable for life science related research
Medchemexpress LLC 5-Sulfosalicylic acid dihydrate | 5965-83-3 | 99.9% | 10 MM 1 ML
5-Sulfosalicylic acid dihydrate is a sulfonated salicylic acid derivative. It is effective against the breast cancer cell line, MCF-7, with less toxicity and possesses antioxidant activities.
- It is a sulfonated salicylic acid derivative.
- It demonstrates effectiveness against the breast cancer cell line, MCF-7, with reduced toxicity.
- It possesses antioxidant activities.
- It can reduce the viability of MCF-7 cells in vitro.
- It is for research use only.
Medchemexpress LLC Terephthalic acid disodium salt | 10028-70-3 | MFCD00013137 | 99.9% | 210.09 g/mol | C8H4Na2O4 | 5 G
Disodium terephthalate is the disodium salt of terephthalic acid, used as a chemical building block and biochemical reagent. It serves as a precursor in polyester (PET) production and is used in laboratory research applications, including formulation of skin tumor models. The material is provided as a solid for bench-scale experimental work.
- High purity suitable for analytical and research applications.
- Molecular weight 210.09 g/mol; formula C8H4Na2O4.
- Soluble in water (~70 mg/mL); ultrasonic agitation may be required.
- Supplied in small pack sizes convenient for laboratory use.
- Useful as a PET precursor and reagent in biochemical assays.
Medchemexpress LLC 5-Sulfosalicylic acid (dihydrate) | 5965-83-3 | 99.9% | 50 G
5-Sulfosalicylic acid dihydrate is a sulfonated salicylic acid derivative that demonstrates effectiveness against the breast cancer cell line MCF-7 with reduced toxicity and possesses antioxidant activities.
- Effective against breast cancer cell line MCF-7
- Reduced toxicity
- Possesses antioxidant activities
- Reduces cell viability in MCF-7 cells at 0.5-4 mM concentrations
- Leads to 63.3% viability in MCF-7 cells at 1 mM and 70.4% in HUVEC control cells after 24 hours
Medchemexpress LLC Setmelanotide monoacetate | 2759937-80-7 | 99.7% | 1177.36 g/mol | C51H72N18O11S2 | 10 MG
Setmelanotide monoacetate is a selective melanocortin 4 receptor (MC4R) agonist peptide intended for laboratory research. It is supplied as a white to off-white solid with supporting analytical data and storage guidance for both solution and bulk formats.
- Potent MC4R agonist with EC50 ≈ 0.27 nM (human and rat).
- Purity: 99.71% by HPLC.
- Molecular weight: 1177.36 g/mol.
- Chemical formula: C51H72N18O11S2.
- Physical appearance: white to off-white solid.
- Storage: store sealed at -20°C; in solvent -80°C up to 6 months, -20°C up to 1 month.
- Available pack sizes: 1 mg, 5 mg, 10 mg, 25 mg; larger sizes available by quote.
- Analytical documents available: data sheet, COA, SDS, HNMR, LCMS.
Medchemexpress LLC 2-Ketoglutaric acid-13C5 | 161096-83-9 | 99.1% | 151.06 | 5 MG
2-Ketoglutaric acid-13C5 is a 13C labeled variant of 2-Ketoglutaric acid, a compound integral to metabolic processes. It participates as an intermediate in the production of ATP or GTP during the Krebs cycle and is a crucial carbon skeleton for nitrogen-assimilatory reactions. Additionally, this compound has been identified as a reversible inhibitor of tyrosinase.
- Can be utilized as a tracer in various research applications.
- Functions as an internal standard for precise quantitative analysis.
- It is a stable isotope-labeled compound for specific studies.
- Essential for key metabolic pathways, including the Krebs cycle.
- Plays a vital role as a carbon skeleton in nitrogen-assimilatory reactions.
- Demonstrates reversible inhibition of tyrosinase enzyme activity.
- Boasts a high purity of 99.1%.
Medchemexpress LLC 2-Ketoglutaric acid potassium | 997-43-3 | 98.0% | 185.20 | 500 MG
2-Ketoglutaric acid potassium, also known as Alpha-Ketoglutaric acid potassium, is an intermediate in the production of ATP or GTP in the Krebs cycle. It is a reversible and orally active inhibitor of tyrosinase, and also acts as a major carbon skeleton for nitrogen-assimilatory reactions.
- Suppresses abnormal intestinal permeability.
- Inhibits delocalization of tight junction proteins from intestinal cells.
- Reduces expression of TNFα in vitro and in vivo.
- Directly binds to TAK1 and inhibits TRAF6-TAK1 interaction.
- Alleviates inflammatory bowel disease (IBD) symptoms and gut microbiota dysbiosis.
Medchemexpress LLC Pentanedioic acid, 2-oxo-, potassium salt (1:1) | 997-43-3 | 98.0% | 185.20 | 1 G
2-Ketoglutaric acid potassium is an intermediate in ATP/GTP production within the Krebs cycle and a reversible, orally active inhibitor of tyrosinase (IC50 = 15 mM). It acts as the primary carbon skeleton for nitrogen-assimilatory reactions. It suppresses abnormal intestinal permeability, prevents tight junction protein delocalization, and inhibits TNFα expression in vitro and in vivo. It binds to TAK1, hindering TRAF6-TAK1 interaction, and alleviates inflammatory bowel disease (IBD) symptoms and gut microbiota dysbiosis.
- Reduces and detoxifies ammonia levels.
- Protective against lipid peroxidation.
- Neuroprotective effect against cyanide poisoning.
- Acts as a precursor for amino acids and nucleotides.
- Improves gut microbiota dysbiosis.
Alkali Scientific 2 Ketoglutaric Acid Monopotassium Salt, 5 G
2-Ketoglutaric Acid Monopotassium Salt (5g) is a highly purified reagent used in laboratory experiments studying metabolic pathways, particularly the Krebs cycle. 2-Ketoglutarate is a critical compound involved in cellular respiration and amino acid metabolism, making this reagent essential in biochemical and metabolic research. The monopotassium salt form is stable and suitable for a variety of applications, including enzyme catalysis, metabolic assays, and organic synthesis. This 5g quantity is perfect for small-scale experiments in laboratories focused on studying energy production, amino acid biosynthesis, and other metabolic processes.
Medchemexpress LLC 2-Ketoglutaric acid (standard) | 328-50-7 | 99.5% | 146.10 | 50 MG
2-Ketoglutaric acid (Standard) is the analytical standard of 2-Ketoglutaric acid. This product is intended for research and analytical applications. It is an intermediate in the production of ATP or GTP in the Krebs cycle and acts as the major carbon skeleton for nitrogen-assimilation reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM).
- The compound is the grade of analytical standard, which is the reference standard supplied assay.
- Commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.