Cumenes
eMolecules 84558-03-2 | 2-(4-ISOPROPYLPHENYL)ETHANAMINE | MFCD06212662 | 5g
WuXi ChemSupply | 2-(4-ISOPROPYLPHENYL)ETHANAMINE | 5g | 599168871 | LN01803386 | 95.000 | 84558-03-2 | MFCD06212662 | 163.264 | C11H17N
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eMolecules 118414-82-7 | Medchem Express | MK-886 | 5mg | 446263888 | HY-14166 | MFCD00876710 | 472.08 | C27H34ClNO2S
ChemScene | (S)-tert-Butyl 2-(5-(4-iodophenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate | 100mg | 768994374 | CS-0618211 | 1242094-29-6 | MFCD30489068 | 439.297 | C18H22IN3O2
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Medchemexpress LLC RO-3 | 1026582-88-6 | 97.3% | 302.37 | 5 MG
RO-3 is a potent, and orally active P2X3 and P2X2/3 antagonist with pIC50s of 5.9 and 7.0 for human homomultimeric P2X3 and heteromultimeric P2X2/3 receptors, respectively. It shows selectivity for P2X3 and P2X2/3 over all other functional homomultimeric P2X receptors (IC50 >10 μM at P2X1,2,4,5,7).
- Reduces afferent nerve activity induced by distension or α,β-meATP in guinea pig ureter-afferent nerve and mouse bladder-pelvic nerve preparations.
- Has activity in several rodent models of pain, as well as in cystometry models optimized to measure various parameters associated with sensory regulation of the micturition reflex.
- Exhibits moderate to high metabolic stability in rat and human hepatocytes and liver microsomes, is highly permeable, orally bioavailable (14%), and has a reasonable in vivo plasma half-life (t1/2=0.41 h) in rats.
- Appearance: Solid.
- Color: Yellow to orange.
Sigma Aldrich Fine Chemicals Biosciences 1,3-Bis(2,6-diisopropylphenyl)-4,5-dihydroimidazolium tetrafluoroborate 95% | Purity: 95% | Mol Wt: 478.42 | 282109-83-5 | MFCD03412153 | 5G
1,3-Bis(2,6-diisopropylphenyl)-4,5-dihydroimidazolium tetrafluoroborate 95% | Purity: 95% | Mol Wt: 478.42 | 282109-83-5 | MFCD03412153 | 5G
Medchemexpress LLC ML-193 | 713121-80-3 | 99.7% | 527.59 | 100 MG
ML-193 (CID 1261822) is a potent and selective antagonist of GPR55, with an IC50 of 221 nM. It demonstrates more than 27-fold selectivity for GPR55 over GPR35, CB1, and CB2. This compound has been shown to improve motor and sensorimotor deficits in rat models of Parkinson's disease.
- Potent and selective GPR55 antagonist.
- High selectivity over GPR35, CB1, and CB2.
- Improves motor and sensorimotor deficits in Parkinson's disease rat models.
- Available in solid and solution forms.
- Detailed solubility information provided.
- Includes detailed handling and storage instructions.
Apexbio Technology LLC GSK 4716 101574-65-6 10mg
GSK 4716 (CAS 101574-65-6) is a small-molecule agonist targeting estrogen-related receptors ERR and ERR It is designed to activate these nuclear receptors thereby modulating mitochondrial function and cellular energy metabolic processes GSK 4716 exerts its biological activity primarily through nuclear receptor-mediated gene regulation pathways Based on these pharmacological properties GSK 4716 holds research potential in investigating mitochondrial bioenergetics metabolic regulation and pathophysiological conditions related to metabolic disorders
Medchemexpress LLC Foropafant | 136468-36-5 | 99.9% | 50 MG
Foropafant (SR27417) is a highly potent, competitive, selective, and orally active antagonist of the platelet-activating factor (PAF) receptor. It exhibits a Ki value of 57 pM for [3H]PAF binding, which is at least 5-fold lower than that of unlabeled PAF itself, and potently inhibits PAF-induced aggregation of rabbit and human platelets. This product is for research use only.
- Highly potent
- Competitive, selective, and orally active antagonist of the platelet-activating factor (PAF) receptor
- Ki value of 57 pM for [3H]PAF binding
- Potently inhibits PAF-induced aggregation of rabbit and human platelets
- Intended for research use only
eMolecules 80225-53-2 | Medchem Express | Rosmanol | 5mg | 434310730 | HY-N5015 | MFCD12031636 | 346.423 | C20H26O5
Medchem Express | Rosmanol | 5mg | 434310730 | HY-N5015 | 80225-53-2 | MFCD12031636 | 346.423 | C20H26O5
Medchemexpress LLC Denudatin B | 87402-88-8 | 5 MG
Denudatin B is an antiplatelet agent that relaxes vascular smooth muscle by inhibiting Ca2+ influx through voltage-gated and receptor-operated Ca2+ channels. It exhibits a nonspecific antiplatelet action.
- Antiplatelet agent
- Relaxes vascular smooth muscle
- Inhibits Ca2+ influx through voltage-gated and receptor-operated Ca2+ channels
- Nonspecific antiplatelet action
- Molecular formula: C21H24O5
- Molecular weight: 356.41
- Target: Calcium channel
- Pathway: Membrane transporter/ion channel; neuronal signaling
- Soluble in DMSO (50 mg/mL)
Medchemexpress LLC Tetrahydropiperine | 23434-88-0 | MFCD17167032 | 99.4% | 289.37 g·mol-1 | C17H23NO3 | 10 MG
Tetrahydropiperine is a research-grade small molecule used to probe inflammatory and survival signaling pathways in cellular and biochemical studies. It acts on NF-κB and MAPK signaling and modulates the PI3K/Akt/mTOR pathway.
- Selective inhibitor of NF-κB and MAPKs, useful for pathway studies.
- Modulates PI3K/Akt/mTOR signaling for research on cell survival.
- High purity solid, suitable for analytical and cellular assays.
- Available in small research pack sizes for screening and mechanism-of-action work.
- Molecular weight approximately 289.37 g·mol-1 and formula C17H23NO3.
eMolecules 1971086-99-3 | Medchem Express | BPN-15477 | 5mg | 719836924 | HY-147149 | 259.7 | C12H10ClN5
Ambeed | 5-Amino-4-methylpyrimidine | 250mg | 525119842 | A203742 | 3438-61-7 | MFCD09038780 | 109.132 | C5H7N3
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eMolecules 26307-50-6 | 4-BROMO-2-ISOPROPYLPHENOL | MFCD00040203 | 1g
ChemScene | (4-Amino-2-methylphenyl)methanol | 100mg | 582645498 | CS-0098091 | 63405-88-9 | MFCD11110504 | 137.182 | C8H11NO
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Medchemexpress LLC HY-100415 1mg Medchemexpress, UKI-1 CAS:220355-63-5 Purity:>98%
Medchemexpress, HY-100415 1mg UKI-1 CAS:220355-63-5 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.