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Filtered Search Results
Medchemexpress LLC Pifusertib hydrochloride | 2930090-28-9 | 99.9% | 460.96 | 5 MG
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Pifusertib hydrochloride is a potent, selective, orally active allosteric Akt inhibitor. It is for research use only and not sold to patients. It triggers anti-myeloma activities and enhances fatal endoplasmic reticulum (ER) stress induced by proteasome inhibition.
- Induces apoptosis and autophagy
- Blocks basal phosphorylation of Akt
- Selectively inhibits Akt
- Triggers G0/G1 arrest
- Enhances bortezomib-induced cytotoxicity
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Medchemexpress LLC Eugenin | 480-34-2 | 99.97% | 206.20 | 5 MG
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Eugenin is a chromone isolated from Formosan Peucedanum japonicum. It exhibits an effective antiplatelet aggregation effect and also shows cytotoxicity against tumor cells. It is suitable for laboratory research.
- Significantly inhibits platelet aggregation induced by multiple inducers
- Exhibits cytotoxic activity against A549, HT-29, and MCF7 tumor cells
- For research use only
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Medchemexpress LLC 1,3-Benzenedicarboxylic acid, 4-fluoro- | 327-95-7 | 99.2% | 184.12 | 100 MG
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4-Fluorobenzene-1,3-dicarboxylic acid is a chemical compound with the molecular formula C8H5FO4 and a molecular weight of 184.12. It typically appears as a white to off-white solid, exhibiting a high purity of 99.2% as determined by HPLC. This compound is suitable for various laboratory applications.
- High purity for reliable experimental results.
- Stable in powder form for extended periods at controlled temperatures.
- Suitable for various research applications requiring a fluorinated benzenedicarboxylic acid.
- Consistent with structure as confirmed by analytical testing.
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Medchemexpress LLC SLMP53-2 | 1826116-38-4 | C26H22N2O2 | 5 MG
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SLMP53-2 is a mutant p53 reactivator that restores wild-type-like conformation and DNA-binding ability of mutp53-Y220C by enhancing its interaction with Hsp70, leading to the reestablishment of p53 transcriptional activity. It can induce cell cycle arrest, apoptosis, and endoplasmic reticulum (ER) stress, and exhibits antitumor activity.
- Restores wild-type-like function to mutant p53.
- Enhances interaction with Hsp70 to reestablish p53 transcriptional activity.
- Induces cell cycle arrest, apoptosis, and endoplasmic reticulum (ER) stress.
- Exhibits antitumor activity.
- Inhibits growth of various cancer cell lines.
- Reduces tumor volume and weight in xenograft mouse models.
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Medchemexpress LLC Flomoxef sodium | 92823-03-5 | 99.3% | 5 MG
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Flomoxef sodium is an oxacephem group antibiotic that exhibits excellent activity against various Gram-positive bacteria.
- Oxacephem group antibiotic
- Active against Gram-positive bacteria
- Purity of 99.3%
- Molecular weight of 518.45
- Chemical formula: C15H17F2N6NaO7S2
- White to off-white solid appearance
- Recommended storage at -20°C, protected from light, under nitrogen.
- Soluble in DMSO and H2O
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Medchemexpress LLC MEFENTRIFLUCONAZOLE 100 mg
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MEFENTRIFLUCONAZOLE 100MG
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Medchemexpress LLC DYRK1-IN-1 50 mg
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DYRK1-IN-1 50MG
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Medchemexpress LLC LS-102 50 mg
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LS-102 50MG
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Medchemexpress LLC TNF-A-IN-2 50 mg
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TNF-A-IN-2 50MG
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Medchemexpress LLC Lartesertib | 2020089-41-0 | 448.45 | C23H21FN6O3 | 10 MG
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Lartesertib is a potent, small-molecule inhibitor of the ATM (ataxia telangiectasia mutated) serine/threonine protein kinase used in research on DNA damage response and tumor radiosensitization. It is supplied as a research reagent with an associated product datasheet; lot-specific purity is provided on the certificate of analysis.
- Potent and selective ATM kinase inhibitor suitable for DNA damage response studies.
- Demonstrated activity in cellular and preclinical models, including radiosensitization.
- Supplied with a product datasheet; certificate of analysis provides lot-specific purity.
- Molecular weight 448.45 and molecular formula C23H21FN6O3.
- CAS number 2020089-41-0; alternate registry entries have been reported in public databases.
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eMolecules 1073-06-9 | 1-Bromo-3-fluorobenzene | Ambeed | MFCD00000326 | 175 | C6H4BrF | 98 | Fc1cccc(Br)c1 | 10g | 525157975
Ambeed | (6R7R)-4-Methoxybenzyl 7-amino-3-(chloromethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride | 250mg | 524987704 | A102740 | 113479-65-5 | MFCD00191255 | 405.290 | C16H18Cl2N2O4S
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Medchemexpress LLC Jnj-54717793 | 1628843-99-1 | 98.1% | 458.41 | C22H18F4N6O | 5 MG
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JNJ-54717793 (CAS 1628843-99-1) is a brain-penetrant, orally active, selective, high-affinity orexin-1 receptor (OX1R) antagonist used in neuroscience research. Supplied as an off-white to pink solid, the compound has formula C22H18F4N6O, molecular weight 458.41, and reported purity around 98%.
- Selective orexin-1 receptor antagonist with high affinity.
- Marked selectivity versus orexin-2 receptor (lower affinity).
- Brain penetrant and orally active for in vivo studies.
- Provided as a powder with recommended cold storage for stability.
- Supplied in small research quantities suitable for preclinical experiments (5 mg).
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Medchemexpress LLC IK-175 (AHR antagonist 5 free base) | 2247950-42-9 | MFCD00824427 | 99.8% | 441.50 g/mol | C25H24FN7 | 5 MG
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IK-175 is a selective, orally active aryl hydrocarbon receptor (AHR) inhibitor supplied for research use. It inhibits AHR translocation and is used in preclinical pharmacology and signaling studies. The compound is provided as a solid powder with high reported purity, recommended DMSO solubility for in vitro work, and defined storage conditions for both powder and solutions.
- Selective AHR inhibition for target-specific studies.
- Suitable for in vitro and in vivo preclinical experiments.
- High purity (99.78%) for reproducible results.
- Soluble in DMSO; in vivo formulation example provided.
- Defined storage conditions for powder and solvent solutions.
- Available in small sample sizes for screening and dose finding.
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Medchemexpress LLC HEMICHOLINIUM 3 10MG
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Hemicholinium 3 is a competitive inhibitor of the high affinity choline transporter (HACU) with a Ki value of 25 nM. Hemicholinium 3, a neuromuscular blocking agent which inhibits the synthesis and the release of acetylcholine (ACh). Hemicholinium 3 inhibits the Epibatidine-evoked contraction and [3H]acetylcholine release with IC50s of 897 nM and 693 nM, respectively.
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ESI SOURCE SOLUTIONS MAGRESYN STREPTAVADIN MAX 2MG
NC2594404 MAGRESYN STREPTAVADIN MAX 2MG
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