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Filtered Search Results
eMolecules 918505-84-7 | PLX-4720 | AstaTech | MFCD14635203 | 413.820 | C17H14ClF2N3O3S | 95.000 | CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(Cl)cc23)c1F | 1g | 268495225
PLX-4720 | AstaTech | 918505-84-7 | MFCD14635203 | 413.820 | C17H14ClF2N3O3S | 95.000 | CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(Cl)cc23)c1F | 1g | 268495225
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Apexbio Technology LLC GSK 2837808A 1445879-21-9 5mg
GSK 2837808A (CAS 1445879-21-9) is a small-molecule inhibitor that selectively targets lactate dehydrogenase A (LDHA) exhibiting potent inhibitory activity with IC50 values of 1 9 nM for LDHA and 14 nM for LDHB In cellular studies GSK 2837808A at 10 M reduced glucose consumption in Snu398 hepatocellular carcinoma cells but not in HepG2 cells indicating cell line-specific metabolic effects Pharmacokinetic analysis in rodents demonstrated rapid clearance following intravenous administration and minimal systemic exposure after oral dosing GSK 2837808A serves as a valuable tool for investigating LDHA function and metabolic regulation in cancer research
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Chemscene ChemScene | 2-(4-(Difluoromethyl)-3-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | 250MG | CS-0147307 | 0.98 | 1310949-75-7| MFCD16996282 | 272.07
ChemScene | 2-(4-(Difluoromethyl)-3-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | 250MG | CS-0147307 | 0.98 | 1310949-75-7| MFCD16996282 | 272.07
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eMolecules 842954-76-1 | [2-Amino-1-(2-fluorophenyl)ethyl]dimethylamine | Combi-Blocks | MFCD06753110 | 182.242 | C10H15FN2 | 95.000 | CN(C)C(CN)c1ccccc1F | 1g | 249356889
[2-Amino-1-(2-fluorophenyl)ethyl]dimethylamine | Combi-Blocks | 842954-76-1 | MFCD06753110 | 182.242 | C10H15FN2 | 95.000 | CN(C)C(CN)c1ccccc1F | 1g | 249356889
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eMolecules 1027971-34-1 | Medchem Express | SB-429201 | 5mg | 713704420 | HY-119017 | 436.511 | C28H24N2O3
Pharmablock | 5-bromo-4-chloropyrimidin-2-amine | 25mg | 551212488 | PB06624 | 1044767-99-8 | MFCD11046979 | 208.440 | C4H3BrClN3
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STA Pharmaceutical Fmoc-4-(2-fluorophenyl)-L-phenylalanine | 10 g | CAS 352525-27-0 | InChIKey ZICPGHNUHMLOMI-NDEPHWFRSA-N
Fmoc-4-(2-fluorophenyl)-L-phenylalanine is a Amino Acid reagent (Subcategory: Aryl AA) sold by WuXi TIDES. Offered in 10 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 352525-27-0
- MDL: No data
- InChIKey: ZICPGHNUHMLOMI-NDEPHWFRSA-N
- Molecular Weight: 481.523
- Molecular Formula: C30H24FNO4
- Purity: ≥95%
- Container Type: 60 mL HDPE
- Pack Size: 10 g
- Net Weight: 10 g
- Gross Weight: 25 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(2'-fluoro-[1,1'-biphenyl]-4-yl)propanoic acid
- SMILES: O=C(OCC1C2=CC=CC=C2C3=CC=CC=C31)N[C@H](C(O)=O)CC4=CC=C(C=C4)C5=CC=CC=C5F
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eMolecules 3-(3-Chloro-4-fluorophenyl)-1H-pyrazole | 154258-78-3 | MFCD03407968 | 1g
Apollo Scientific | 3-(3-Chloro-4-fluorophenyl)-1H-pyrazole | 1g | 562461860 | PC300891 | | 154258-78-3 | MFCD03407968 | 196.610 | C9H6ClFN2
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Medchemexpress LLC (2S)-2-(4-fluorophenyl)-1-[(4-methylphenyl)sulfonyl]-pyrrolidine | 298690-60-5 | MFCD20270617 | 99.7% | 319.39 | C17H18FNO2S | 2 MG
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Ro 67-7476 is a selective positive allosteric modulator (PAM) of the metabotropic glutamate receptor 1 (mGluR1). It potentiates glutamate-induced calcium release and activates ERK1/2 signaling in cellular assays; supplied for research use only.
- Selective positive allosteric modulator of mGluR1.
- Potentiates glutamate-induced calcium release (EC50 = 60.1 nM).
- Activates ERK1/2 phosphorylation in cell-based assays (EC50 = 163.3 nM).
- High reported purity suitable for biochemical and pharmacology studies.
- Available as solid and as DMSO solution for assay flexibility.
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Medchemexpress LLC 11H-indeno[1,2-b]quinoxalin-11-one O-(2-furanylcarbonyl)oxime | 312538-03-7 | 99.4% | 341.32 g·mol⁻1 | C20H11N3O3 | 100 MG
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IQ-3 is a small-molecule inhibitor of the c-Jun N-terminal kinase (JNK) family with preference for JNK3. It binds JNK1, JNK2, and JNK3 with reported Kd values of 0.24 μM, 0.29 μM, and 0.066 μM, respectively. Supplied as an off-white to light yellow solid, IQ-3 is used in research to probe JNK signaling in vitro and in vivo; solubility, purity, and storage recommendations are provided on the product datasheet.
- Preference for JNK3 over JNK1 and JNK2.
- Low-micromolar to sub-micromolar binding affinities for JNK isoforms.
- High purity (99.4%).
- Available as a solid and in DMSO solution for convenient dosing.
- Soluble in DMSO (25 mg/mL); sonication recommended.
- Powder storage at -20°C with defined solvent stability.
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Medchemexpress LLC BSJ-02-162 | 2139329-47-6 | 98.1% | C43H49N11O7 | 100 MG
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BSJ-02-162 is a potent PROTAC degrader targeting Cyclin-Dependent Kinases 4 and 6. It consists of a thalidomide-based E3 ligase ligand, a Palbociclib-derived target protein ligand, and a PROTAC linker. This compound works by harnessing the cell's ubiquitin-proteasome system to induce the degradation of CDK4/6 proteins, offering an advantage over traditional small-molecule inhibitors. Intended for research use only.
- Potent PROTAC CDK4/6 degrader with a novel mechanism.
- Multi-component structure for targeted degradation.
- High purity of 98.07% for reliable results.
- Ideal for research in cell cycle, DNA damage, and cancer.
- Available in various solid and solution quantities.
- Includes comprehensive documentation for thorough understanding.
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Medchemexpress LLC Egfr-in-5 | 2225887-26-1 | 99.5% | 571.69 g·mol-1 | C31H38FN9O | 5 MG
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EGFR-IN-5 is a small-molecule inhibitor of the epidermal growth factor receptor (EGFR) that displays low-nanomolar potency against wild-type EGFR and clinically relevant resistant mutants. It is supplied for research use with confirmed high purity and documented solubility and storage conditions suitable for biochemical and cellular studies.
- Low-nanomolar inhibitory activity against EGFR and common resistant mutants (IC50: 10.4 nM for wild-type; 1.1 nM for L858R; 34 nM for L858R/T790M; 7.2 nM for L858R/T790M/C797S).
- High chemical purity suitable for research applications.
- Soluble in DMSO at ≥ 100 mg/mL; formulation data available for in vivo dosing.
- Stable as a powder at -20°C for long-term storage; solvent stability documented at -80°C (6 months) and -20°C (1 month).
- Appropriate for biochemical assays and preclinical cellular studies.
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eMolecules 944898-08-2 | 5-(4-Fluorophenyl)-1,3,4-oxadiazole-2-carboxylic acid | ChemScene | MFCD10001469 | 208.148 | C9H5FN2O3 | 98.000 | OC(=O)c1nnc(o1)-c1ccc(F)cc1 | 100mg | 714214795
5-(4-Fluorophenyl)-1,3,4-oxadiazole-2-carboxylic acid | ChemScene | 944898-08-2 | MFCD10001469 | 208.148 | C9H5FN2O3 | 98.000 | OC(=O)c1nnc(o1)-c1ccc(F)cc1 | 100mg | 714214795
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Medchemexpress LLC N-[(1R)-1-(3-cyclopentyloxyphenyl)ethyl]-3-[(2,4-dioxopyrimidin-1-yl)methoxy]propane-1-sulfonamide | 1198221-21-4 | 99.9% | 451.54 g/mol | C21H29N3O6S | 10MG
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TAS-114 is a small-molecule, orally active dual inhibitor of dUTPase and dihydropyrimidine dehydrogenase (DPD) used in preclinical and clinical research to enhance the efficacy of fluoropyrimidine-based chemotherapy and to probe nucleotide metabolism in cancer models.
- Dual inhibition of dUTPase and DPD for combination chemotherapy studies.
- Orally active small molecule suitable for in vitro and in vivo research.
- High reported purity (99.89%).
- Molecular formula C21H29N3O6S; MW 451.54 g/mol.
- Recommended storage: 4°C under nitrogen; in solvent: -80°C (6 months) or -20°C (1 month).
- Analytical data available: COA, SDS, data sheet, and spectral data.
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Medchemexpress LLC HY-115579 10mg Medchemexpress, MALAT1-IN-1 CAS:827327-28-6 Purity:>98%
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Medchemexpress, HY-115579 10mg MALAT1-IN-1 CAS:827327-28-6 MALAT1-IN-1 (compounds 5) is a potent and specific Malat1 (Metastasis-associated lung adenocarcinoma transcript 1) inhibitor. MALAT1-IN-1 modulated Malat1 downstream genes in a dose-dependent manner without affecting expression of nuclear enriched abundant transcript 1 (Neat1) . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Enzo Life Sciences Rucaparib (free base) (200mg). CAS: 283173-50-2
Rucaparib is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
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