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Filtered Search Results
Medchemexpress LLC Gelsevirine | 38990-03-3 | 5 MG
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Gelsevirine is the major alkaloid in Gelsemium elegans with potent anxiolytic effects. The anxiolytic mechanism of Gelsevirine may involve the agonist action of the glycine receptor in the brain. Gelsevirine also exhibits anti-proliferation activity with IC50 values of 1.41 mM and 1.22 mM for SW480 cells and MGC80-3 cells, respectively.
- Major alkaloid in Gelsemium elegans
- Potent anxiolytic effects
- Anxiolytic mechanism may involve agonist action of glycine receptor
- Exhibits anti-proliferation activity
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![Medchemexpress LLC N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodoanilino)pyridine-4-carboxamide | 1236699-92-5 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/HY-12042.jpg-250.jpg)
Medchemexpress LLC N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodoanilino)pyridine-4-carboxamide | 1236699-92-5 | 5 MG
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Pimasertib is a selective, ATP non-competitive allosteric inhibitor of MEK1/2 used in preclinical research to investigate MAPK/ERK signaling and antiproliferative effects. Supplied in a small, precise quantity for laboratory assays.
- Selective MEK1/2 inhibition for pathway-targeted studies
- ATP non-competitive allosteric mechanism of action
- Supplied as a 5 mg solid for small-scale experiments
- Well characterized by CAS and chemical identifiers
- Suitable for cell-based and biochemical assays
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eMolecules 96574-01-5 | (R)-3-(3,4-Dihydroxyphenyl)-2-(((E)-3-(2-((E)-3,4-dihydroxystyryl)-3,4-dihydroxyphenyl)acryloyl)oxy)propanoic acid | MFCD08458447 | 50mg
Ambeed | (R)-3-(3,4-Dihydroxyphenyl)-2-(((E)-3-(2-((E)-3,4-dihydroxystyryl)-3,4-dihydroxyphenyl)acryloyl)oxy)propanoic acid | 50mg | 515725794 | A695449 | 96574-01-5 | MFCD08458447 | 494.452 | C26H22O10
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Medchemexpress LLC FBPase-1 inhibitor-1 | 883973-99-7 | 99.1% | 377.63 | 50 MG
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FBPase-1 inhibitor-1 (Compound 1) is an allosteric FBPase-1 inhibitor. It blocks gluconeogenesis by inhibiting FBPase-1.
- IC50 of 3.3 μM or 3.9 μM
- Can be used for the research of type 2 diabetes (t2dm)
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eMolecules 3-BROMO-4,5-DIFLUOROBENZENE-1,2-DIAMINE | 153505-35-2 | MFCD30223938 | 1g
AstaTech | 3-BROMO-4,5-DIFLUOROBENZENE-1,2-DIAMINE | 1g | 388699528 | 89423 | 95.000 | 153505-35-2 | MFCD30223938 | 223.021 | C6H5BrF2N2
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Chem-Impex International, Inc. 2-Fluoroaniline | MFCD00007642 | 100G
2-Fluoroaniline, MFCD00007642, 100G
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Medchemexpress LLC HY-13058 5mg Medchemexpress, ADX-47273 CAS:851881-60-2 Purity:>98%
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Medchemexpress, HY-13058 5mg ADX-47273 CAS:851881-60-2 ADX-47273 is a potent, selective and brain-penetrant mGluR5 positive allosteric modulator (PAM), with an EC50 of 0.17 μM for potentiation of glutamate (50 nM) response. ADX-47273 has antipsychotic and procognitive activities. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC BMS 299897 | 290315-45-6 | 99.6% | C24H21ClF3NO4S | 5 MG
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BMS 299897 is a sulfonamide γ-secretase inhibitor that inhibits Aβ production with an IC50 of 7 nM in HEK293 cells overexpressing amyloid precursor protein (APP).
- Reduces levels of Aβ peptides.
- Decreases Aβ peptides to 20-50% of vehicle control at 1 μM.
- Reduces retrograde QD-BDNF signals, increases anterograde signals.
- Shows dose- and time-dependent reductions of Aβ in brain, CSF, and plasma in mice.
- Reduces brain and plasma Aβ1-40.
- Increases brain concentrations of APP-carboxy-terminal fragments.
- Attenuates Aβ25-35-induced Aβ1-42 seeding and toxicity.
- Blocks Aβ25-35-induced deficits in spontaneous alternation or novel object recognition.
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eMolecules 1211182-74-9 | 2-(4-Fluorophenyl)amino-4-(2-hydroxyphenyl)-1,3-thiazole hydrobromide | Apollo Scientific | MFCD08458094 | 367.240 | C15H12BrFN2OS | 97.000 | Br.Oc1ccccc1-c1csc(Nc2ccc(F)cc2)n1 | 1g | 562442766
2-(4-Fluorophenyl)amino-4-(2-hydroxyphenyl)-1,3-thiazole hydrobromide | Apollo Scientific | 1211182-74-9 | MFCD08458094 | 367.240 | C15H12BrFN2OS | 97.000 | Br.Oc1ccccc1-c1csc(Nc2ccc(F)cc2)n1 | 1g | 562442766
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eMolecules 886761-82-6 | 2-(3-Chloro-2-fluorophenyl)ethanol | Apollo Scientific | MFCD06660361 | 174.600 | C8H8ClFO | 95.000 | OCCc1cccc(Cl)c1F | 5g | 562456214
2-(3-Chloro-2-fluorophenyl)ethanol | Apollo Scientific | 886761-82-6 | MFCD06660361 | 174.600 | C8H8ClFO | 95.000 | OCCc1cccc(Cl)c1F | 5g | 562456214
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eMolecules 1-(3-Bromo-4-fluorophenyl)-2,2,2-trifluoroethanol | 150698-79-6 | MFCD16067892 | 1g
Apollo Scientific | 1-(3-Bromo-4-fluorophenyl)-2,2,2-trifluoroethanol | 1g | 562428825 | PC53306 | | 150698-79-6 | MFCD16067892 | 273.025 | C8H5BrF4O
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eMolecules 3906-87-4 | 2,5-DICARBOXY-FLUOROBENZENE | AstaTech | MFCD03407274 | 184.122 | C8H5FO4 | 95.000 | OC(=O)c1ccc(C(O)=O)c(F)c1 | 5g | 449717951
2,5-DICARBOXY-FLUOROBENZENE | AstaTech | 3906-87-4 | MFCD03407274 | 184.122 | C8H5FO4 | 95.000 | OC(=O)c1ccc(C(O)=O)c(F)c1 | 5g | 449717951
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eMolecules 1379336-54-5 | Methyl 2-bromo-4,6-difluorobenzoate | Apollo Scientific | MFCD18642939 | 251.027 | C8H5BrF2O2 | 97.000 | COC(=O)c1c(F)cc(F)cc1Br | 1g | 562428160
Methyl 2-bromo-4,6-difluorobenzoate | Apollo Scientific | 1379336-54-5 | MFCD18642939 | 251.027 | C8H5BrF2O2 | 97.000 | COC(=O)c1c(F)cc(F)cc1Br | 1g | 562428160
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eMolecules 461-96-1 | 1-Bromo-3,5-difluorobenzene | Oakwood Chemical | MFCD00010305 | 192.991 | C6H3BrF2 | 99.000 | Fc1cc(F)cc(Br)c1 | 100g | 537661782
1-Bromo-3,5-difluorobenzene | Oakwood Chemical | 461-96-1 | MFCD00010305 | 192.991 | C6H3BrF2 | 99.000 | Fc1cc(F)cc(Br)c1 | 100g | 537661782
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eMolecules 351325-31-0 | Methyl 5-bromo-2,4-difluorobenzoate | Combi-Blocks | MFCD16038827 | 251.027 | C8H5BrF2O2 | 98.000 | COC(=O)c1cc(Br)c(F)cc1F | 1g | 290685517
Methyl 5-bromo-2,4-difluorobenzoate | Combi-Blocks | 351325-31-0 | MFCD16038827 | 251.027 | C8H5BrF2O2 | 98.000 | COC(=O)c1cc(Br)c(F)cc1F | 1g | 290685517
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