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Filtered Search Results
Matrix Scientific 1-BROMO-3-CHLORO-2-FLUOROBE-5G
1-Bromo-3-chloro-2-fluorobenzene, 5g,C6H3BrClF, MFCD03412182, mw 209.45, [144584-65-6]
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eMolecules 5701-87-1 | 2-Amino-3,4-dimethoxybenzoic acid | MFCD00038792 | 1g
Ambeed | 2-Amino-3,4-dimethoxybenzoic acid | 1g | 552736385 | A485990 | 5701-87-1 | MFCD00038792 | 197.190 | C9H11NO4
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eMolecules 2146-07-8 | 4-Fluoroaniline hydrochloride | MFCD00035500 | 5g
AstaTech | 4-CHLORO-6-ISOPROPYL-THIENO[23-D]PYRIMIDINE | 0.25g | 268498542 | 71498 | 95.000 | 439692-52-1 | MFCD04973929 | 212.700 | C9H9ClN2S
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Apexbio Technology LLC ML161 423735-93-7 10mg
ML161 (CAS 423735-93-7) is a selective small-molecule inhibitor targeting protease-activated receptor-1 (PAR1) a G protein-coupled receptor implicated in signal transduction pathways associated with tumor progression ML161 exhibits potent inhibitory activity against PAR1 with an IC of 0 26 M In human platelet assays ML161 suppresses thrombin-induced platelet activation in a dose-dependent manner as evidenced by reduced P-selectin expression Additionally ML161 inhibits P-selectin surface expression during granule secretion (EC 0 3 M) and blocks SFLLRN-stimulated platelet aggregation This compound is utilized in studies of PAR1-mediated signaling and platelet function
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eMolecules 511295-00-4 | 2,3,4,6-Tetrafluorophenylboronic acid | Combi-Blocks | MFCD04039309 | 193.890 | C6H3BF4O2 | 95.000 | OB(O)c1c(F)cc(F)c(F)c1F | 1g | 117525893
2,3,4,6-Tetrafluorophenylboronic acid | Combi-Blocks | 511295-00-4 | MFCD04039309 | 193.890 | C6H3BF4O2 | 95.000 | OB(O)c1c(F)cc(F)c(F)c1F | 1g | 117525893
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Medchemexpress LLC Riviciclib hydrochloride | 920113-03-7 | 99.1% | 438.30 | 100 MG
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Riviciclib hydrochloride is a potent cyclin-dependent kinase (CDK) inhibitor. It inhibits CDK9-cyclinT1, CDK4-cyclin D1, and CDK1-cyclinB with IC50s of 20 nM, 63 nM, and 79 nM, respectively, and shows antitumor activity on cisplatin-resistant cells.
- Potent cyclin-dependent kinase (CDK) inhibitor.
- Inhibits CDK9-cyclinT1 (IC50: 20 nM), CDK4-cyclin D1 (IC50: 63 nM), and CDK1-cyclinB (IC50: 79 nM).
- Shows antitumor activity on cisplatin-resistant cells.
- Induces G1-G2 arrest and apoptosis in promyelocytic leukemia cells.
- Reduces cyclin D1, Cdk4, and Rb levels in H-460 cells.
- Active in various human cancer cell lines including colon carcinoma, osteosarcoma, cervical carcinoma, and bladder carcinoma cells.
- Significant in vivo efficacy in tumor models, inhibiting growth in human colon carcinoma HCT-116 xenograft and H-460 tumor xenograft in mice.
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Medchemexpress LLC Cdk9-in-7 | 2369981-71-3 | 98.1% | 547.71 | C29H37N7O2S | 5MG
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CDK9-IN-7 is a selective, potent, orally active small-molecule inhibitor of CDK9/cyclin T for research use. It exhibits strong biochemical potency (IC50 = 11 nM), preferential selectivity versus other CDKs, and has demonstrated antitumor activity in preclinical non-small-cell lung cancer models by inducing apoptosis, causing G2 cell-cycle arrest, and reducing cancer stemness.
- Selective CDK9/cyclin T inhibition with reduced activity against CDK4 and CDK6
- Potent biochemical activity (IC50 = 11 nM) for target engagement studies
- Demonstrated antitumor effects in NSCLC models, including apoptosis and G2 arrest
- Suitable for in vitro and in vivo research, including oral administration studies
- Available as powder and as a 10 mM solution in DMSO for screening
- High purity (~98.1%) for reliable experimental results
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eMolecules 851881-60-2 | Medchem Express | ADX-47273 | 5mg | 446262353 | HY-13058 | MFCD17167026 | 369.372 | C20H17F2N3O2
Medchem Express | ADX-47273 | 5mg | 446262353 | HY-13058 | 851881-60-2 | MFCD17167026 | 369.372 | C20H17F2N3O2
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eMolecules 1491150-77-6 | Medchem Express | Syk-IN-1 | 5mg | 559839583 | HY-12657 | 366.429 | C18H22N8O
Ambeed | 3-Bromo-N-methoxy-N-methylbenzamide | 5g | 600835375 | A252486 | 207681-67-2 | MFCD02684302 | 244.088 | C9H10BrNO2
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eMolecules 635323-95-4 | Medchem Express | F-15599 | 5mg | 415688302 | HY-19863 | MFCD28502284 | 394.85 | C19H21ClF2N4O
Medchem Express | F-15599 | 5mg | 415688302 | HY-19863 | 635323-95-4 | MFCD28502284 | 394.850 | C19H21ClF2N4O
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eMolecules 1401090-53-6 | Medchem Express | Ibiglustat | 2mg | 446267809 | HY-16743 | MFCD28502073 | 389.49 | C20H24FN3O2S
Medchem Express | MSP-3 | 5mg | 781212789 | HY-118785 | 1820968-63-5 | 305.390 | C16H19NO3S
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Medchemexpress LLC Florbetapir (18F)-radiolabeled styrylpyridine tosylate precursor | 1205550-99-7 | 99.7% | 100 MG
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A styrylpyridine tosylate precursor used to synthesize 18F-radiolabeled florbetapir-type tracers for positron emission tomography (PET) research.
- High chemical purity suitable for radiolabeling workflows.
- Used to synthesize 18F-labeled PET imaging agents targeting amyloid plaques.
- White to yellow solid; easy handling and storage as a dry powder.
- Long-term stability when stored at -20°C; solvent solutions require colder storage.
- Available in small research-scale quantities for tracer development.
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![eMolecules 451485-60-2 | 3-{3-[(2-Chloro-6-fluorobenzyl)oxy]phenyl}-1H-pyrazole | Apollo Scientific | MFCD03425750 | 302.730 | C16H12ClFN2O | 95.000 | Fc1cccc(Cl)c1COc1cccc(c1)-c1cc[nH]n1 | 1g | 562431119](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502153320.JPG-250.jpg)
eMolecules 451485-60-2 | 3-{3-[(2-Chloro-6-fluorobenzyl)oxy]phenyl}-1H-pyrazole | Apollo Scientific | MFCD03425750 | 302.730 | C16H12ClFN2O | 95.000 | Fc1cccc(Cl)c1COc1cccc(c1)-c1cc[nH]n1 | 1g | 562431119
3-{3-[(2-Chloro-6-fluorobenzyl)oxy]phenyl}-1H-pyrazole | Apollo Scientific | 451485-60-2 | MFCD03425750 | 302.730 | C16H12ClFN2O | 95.000 | Fc1cccc(Cl)c1COc1cccc(c1)-c1cc[nH]n1 | 1g | 562431119
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eMolecules 5527-94-6 | 4-Chloro-3-fluorotoluene | Ambeed | MFCD00143295 | 144.570 | C7H6ClF | 98.000 | Cc1ccc(Cl)c(F)c1 | 1g | 552760402
4-Chloro-3-fluorotoluene | Ambeed | 5527-94-6 | MFCD00143295 | 144.570 | C7H6ClF | 98.000 | Cc1ccc(Cl)c(F)c1 | 1g | 552760402
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Medchemexpress LLC HY-101815 1mg Medchemexpress, Lidanserin CAS:73725-85-6 Purity:>98%
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Medchemexpress, HY-101815 1mg Lidanserin CAS:73725-85-6 Lidanserin is a drug which acts as a combined 5-HT 2A and α 1 -adrenergic receptor antagonist. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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