Fluorobenzenes

Medchemexpress LLC PHD-1-IN-1 | 2009343-14-8 | 99.2% | 220.23 | 50 MG

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PHD-1-IN-1 is an orally active and potent HIF prolylhydroxylase domain-1 (PHD-1) inhibitor with an IC50 of 0.034 μM. It has a unique monodentate binding interaction with the active site Fe2+ ion and induces the formation of an "Arg367-out" pocket.

• Orally active and potent HIF prolylhydroxylase domain-1 (PHD-1) inhibitor
• IC50 of 0.034 μM (PHD-1)
• Unique monodentate binding interaction with the active site Fe2+ ion
• Induces the formation of an "Arg367-out" pocket

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Medchemexpress LLC Phd-1-in-1 | 2009343-14-8 | 99.2% | 220.23 | C13H8N4 | 5 MG

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PHD-1-IN-1 is a potent, orally active small-molecule inhibitor of hypoxia-inducible factor prolyl-hydroxylase domain-1 (PHD-1) for preclinical research into HIF regulation and hypoxia signaling. It binds the active-site Fe2+ with a unique monodentate interaction and induces an Arg367-out pocket. Supplied as a white to off-white solid with high purity for in vitro and in vivo studies.

• Potent PHD-1 inhibition (IC50 0.034 μM).
• Unique monodentate binding to the active-site iron that alters pocket conformation.
• High purity suitable for research and assay development.
• Soluble in DMSO; manufacturer provides in vivo formulation protocols.
• Stable powder storage conditions for long-term preservation.

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Medchemexpress LLC R-NVS-ZP7-4 50mg | 2517682-14-1 | 50 MG

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(R)-NVS-ZP7-4 is the R-enantiomer of NVS-ZP7-4, a small-molecule inhibitor of the zinc transporter SLC39A7 (ZIP7) supplied as an optically pure research compound for biochemical and cellular studies targeting ER zinc homeostasis, Notch signaling, and ferroptosis-related pathways.

• Optically pure R-enantiomer for stereochemistry-specific studies.
• High purity (~98.8%) suitable for biochemical and cellular assays.
• Solid, light yellow to yellow form; stable when stored at -20°C.
• Solvent storage: -80°C for up to 6 months, -20°C for up to 1 month (protect from light).
• Useful for probing ZIP7 function, ER zinc levels, Notch signaling, and ferroptosis mechanisms.

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eMolecules​ 1-(4-BROMO-2-FLUOROPHENYL)ETHANAMINE | 1034266-14-2 | MFCD18701996 | 1g

AstaTech | 1-(4-BROMO-2-FLUOROPHENYL)ETHANAMINE | 1g | 323613050 | N10675 | 95.000 | 1034266-14-2 | MFCD18701996 | 218.069 | C8H9BrFN

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eMolecules​ 1-(4-BROMO-3-FLUOROPHENYL)-2-CHLOROETHANONE | 1260857-14-4 | MFCD11847747 | 1g

AstaTech | 1-(4-BROMO-3-FLUOROPHENYL)-2-CHLOROETHANONE | 1g | 410712881 | 80196 | 97.000 | 1260857-14-4 | MFCD11847747 | 251.480 | C8H5BrClFO

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Medchemexpress LLC CCR2 antagonist 4 hydrochloride | 1313730-14-1 | 99.9% | 476.32 g/mol | C21H22Cl2F3N3O2 | 25 MG

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CCR2 antagonist 4 hydrochloride is a small-molecule CCR2 receptor antagonist provided for research use. It inhibits CCR2b (IC50 ≈ 180 nM) and potently blocks MCP-1-induced chemotaxis (IC50 ≈ 24 nM); the compound is supplied as a solid with reported high purity for in vitro pharmacology and chemotaxis studies.

• High reported purity (≈99.9%).
• Solid form suitable for storage and handling.
• Molecular formula C21H22Cl2F3N3O2; molecular weight 476.32 g/mol.
• Shows CCR2b inhibition (IC50 180 nM) and inhibits MCP-1-induced chemotaxis (IC50 ≈24 nM).
• Available in small research pack sizes, for example 25 mg.

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Medchemexpress LLC CCR2 antagonist 4 (hydrochloride) | 1313730-14-1 | MFCD16618399 | 99.9% | 476.32 | C21H22Cl2F3N3O2 | 5 MG

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CCR2 antagonist 4 hydrochloride is a small-molecule research compound that selectively antagonizes the chemokine receptor CCR2b. It is used to study CCR2-mediated chemotaxis and inflammatory signaling and is supplied as a white to off-white solid with high reported purity and defined physicochemical data.

• Potent CCR2b antagonist with reported IC50 180 nM.
• Inhibits MCP-1-induced chemotaxis (IC50 24 nM).
• High purity (99.91%).
• White to off-white solid appearance.
• Molecular weight 476.32.
• Available in small research pack sizes including 5 mg.

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Medchemexpress LLC CCR2 antagonist 4 (hydrochloride) | 1313730-14-1 | 99.9% | 476.32 g/mol | C21H22Cl2F3N3O2 | 50 MG

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CCR2 antagonist 4 hydrochloride is a potent, selective CCR2 receptor antagonist supplied as the hydrochloride salt for biochemical and cell-based research. The compound shows activity against CCR2b and inhibits MCP-1-induced chemotaxis in cellular assays.

• Hydrochloride salt suitable for research use.
• Molecular formula C21H22Cl2F3N3O2; molecular weight 476.32 g/mol.
• Purity 99.9% (as supplied).
• Available in small research pack sizes, including 50 mg.
• Reported CCR2b and chemotaxis inhibitory activity in cell-based assays.

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Medchemexpress LLC CCR2 antagonist 4 hydrochloride | 1313730-14-1 | MFCD16618399 | 99.9% | 476.32 g/mol | C21H22Cl2F3N3O2 | 10 MG

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CCR2 antagonist 4 hydrochloride is a research-grade small-molecule antagonist of the CC chemokine receptor 2 (CCR2), supplied as the hydrochloride salt for laboratory research use. It is used as a tool compound in studies of inflammation and chemotaxis. CAS 1313730-14-1; molecular formula C21H22Cl2F3N3O2; molecular weight 476.32 g/mol.

• High purity suitable for research applications.
• Provided as the hydrochloride salt for improved handling and stability.
• Intended for in vitro research and chemotaxis studies.
• Supplied in a 10 mg package.

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Medchemexpress LLC CCR2 antagonist 4 hydrochloride | 1313730-14-1 | MFCD16618399 | 99.9% | 476.32 g/mol | C21H22Cl2F3N3O2 | 100 MG

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CCR2 antagonist 4 hydrochloride is a potent, selective small-molecule antagonist of the CC chemokine receptor 2 (CCR2b), used in preclinical research to probe CCR2-mediated signaling and chemotaxis. Reported activity includes an IC50 of 180 nM for CCR2b and inhibition of MCP-1-induced chemotaxis with an IC50 of 24 nM. Supplied as the hydrochloride salt with high purity suitable for biochemical and cellular assays.

• Molecular formula: C21H22Cl2F3N3O2
• Molecular weight: 476.32 g/mol
• Purity: 99.9%
• Target: CCR2b; IC50 180 nM
• Functional assay: MCP-1 chemotaxis IC50 24 nM
• Form: hydrochloride salt, solid powder
• Typical quantity: 100 MG

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eMolecules​ Ambeed / 14-Benzenedicarboxaldehyde 25-diethoxy- / 100mg / 600827956 / A1154736 / / 56766-03-1 / [null] / 222.240 / C12H14O4

Ambeed / 14-Benzenedicarboxaldehyde 25-diethoxy- / 100mg / 600827956 / A1154736 / / 56766-03-1 / [null] / 222.240 / C12H14O4

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eMolecules​ Medchem Express / CCR2 antagonist 4 (hydrochloride) / 5mg / 536983804 / HY-103362 / / 1313730-14-1 / MFCD16618399 / 476.320 / C21H22Cl2F3N3O2

Medchem Express / CCR2 antagonist 4 (hydrochloride) / 5mg / 536983804 / HY-103362 / / 1313730-14-1 / MFCD16618399 / 476.320 / C21H22Cl2F3N3O2

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Medchemexpress LLC N-(4-(4-(2-(diethylamino)-2-oxo-1-phenylethyl)piperazinyl)-3-fluorophenyl)-2-(3-pyridyl)benzamide | 1094873-14-9 | MFCD18782744 | 98.0% | C34H36FN5O2 | 10MG

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JNJ-31020028 is a selective, brain-penetrant antagonist of the neuropeptide Y Y2 receptor used in neuroscience research. It demonstrates high potency in human and rodent Y2 assays and is supplied as a well-characterized, high-purity research compound with documented solubility and storage recommendations for powder and solution forms.

• High purity suitable for research applications.
• Brain-penetrant antagonist of neuropeptide Y Y2 receptor.
• Demonstrated potency in human and rodent assays.
• Compatible with common in vitro and in vivo formulations.
• Documented solubility and storage conditions for reproducibility.

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Medchemexpress LLC (S)-2-(2-((3'-(1-amino-2-hydroxyethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)acetic acid | 1646682-14-5 | 99.2% | 377.43 g/mol | C23H23NO4 | 5 MG

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FD-IN-1 is a small-molecule research compound that selectively inhibits complement Factor D (FD). It demonstrates potent biochemical activity and functional inhibition in whole-blood assays, and is supplied as a solid or DMSO stock for use in in vitro and in vivo preclinical studies.

• Selective factor D inhibition with IC50 of 12 nM.
• Functional inhibition in MAC deposition whole-blood assay (IC50 0.26 μM).
• High purity suitable for research (≈99.2% reported).
• Available as solid samples and as a DMSO stock solution for flexible use.
• Soluble in DMSO and compatible with common in vivo formulation vehicles.
• Recommended storage conditions for powder and stock solutions to preserve stability.

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Accela Chembio Inc (8r | 9s | 10r | 13s | 14s)-10 | 13-dimethylspiro[7 | 8 | 9 | 11 | 12 | 13 | 15 | 16-octahydro-6h-cyclopenta[a]phenanthrene-6 | 2'-oxirane]-3 | 17(10h | 14h)-dione | 1g | 184972-12-1 | MFCD19442795 | 97+% | Shelf Life: 1260 Days | Light Sensitive/+4

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(8r | 9s | 10r | 13s | 14s)-10 | 13-dimethylspiro[7 | 8 | 9 | 11 | 12 | 13 | 15 | 16-octahydro-6h-cyclopenta[a]phenanthrene-6 | 2'-oxirane]-3 | 17(10h | 14h)-dione | 1g | 184972-12-1 | MFCD19442795 | 97+% | Shelf Life: 1260 Days | Light Sensitive/+4

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