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RORγt Inverse agonist 6 (compound 43) is a RORγt inverse agonist for the study of Th17-driven autoimmune diseases. It suppresses IL-17A gene expression by IL-23 stimulation.
RORγt inverse agonist.
Used for studying Th17-driven autoimmune diseases.
Suppresses IL-17A gene expression.
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RORγt Inverse agonist 6 is a research compound acting as an inverse agonist of the transcription factor RORγt. It is used in preclinical studies to investigate Th17-mediated inflammation and has been reported to suppress IL-17A expression following IL-23 stimulation in vivo.
Inverse agonist activity against RORγt suitable for mechanistic studies.
Demonstrated suppression of IL-17A expression in vivo.
Available as solid powder and as a ready-to-use DMSO solution for assay flexibility.
High purity (~98.97%) appropriate for biochemical and cellular assays.
Characterized by molecular formula C28H29ClN6O5 and molecular weight 565.02.
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Medchemexpress, HY-19733 5mg Lumateperone (tosylate) CAS:1187020-80-9 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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TC11 is a research-grade small molecule that functions as an MCL1 degrader and activator of caspase-9 and CDK1. It is a phenylacetylamide derivative that promotes MCL1 degradation and induces apoptotic death during prolonged mitotic arrest; supplied for laboratory research use only.
High purity (99.6%).
Molecular weight 322.40 g/mol.
Chemical formula C20H22N2O2.
Solid, white to yellow appearance.
Store at 4°C and protect from light; in solvent store at -80°C (6 months) or -20°C (1 month).
Functions as an MCL1 degrader and caspase-9 and CDK1 activator in cell studies.
Intended for research use only; not for human or clinical applications.
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CDK9-IN-7 is a selective, potent cyclin-dependent kinase 9 (CDK9) inhibitor (compound 21e) used for cell-cycle and apoptosis research. It exhibits low-nanomolar inhibitory activity and is supplied as a high-purity research reagent in powder and solution formats.
Selective CDK9 inhibition with IC50 ≈ 11 nM.
Low nanomolar potency suitable for in vitro and in vivo studies.
High purity (≈98.1%).
Available as powder and as a 10 mM solution in DMSO.
Multiple package sizes, including a 50 mg option.
Recommended storage: powder at -20°C (long term) or 4°C; in solvent at -80°C for extended storage.
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CDK9-IN-15 is a small-molecule research compound described as a potent cyclin-dependent kinase 9 (CDK9) inhibitor, suitable for biochemical and cellular studies investigating CDK9-related pathways. It is supplied as a solid and intended for laboratory research use only.
Potent CDK9 inhibition suitable for biochemical and cellular assays.
High purity (98.9%) supporting reproducible experimental results.
Molecular formula C16H11N3OS; molecular weight 293.34 g·mol-1.
Solid form, brown to black; typically soluble in DMSO for assay preparation.
Recommended storage: 4°C protected from light; in solvent store at -80°C for long-term.
Available in small milligram pack sizes appropriate for research applications.
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