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Fluorobenzenes

Organic compounds considered aryl halides that consist of a phenyl group with a fluorine atom substitution in the following structure: C₆H₅F.

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1

Medchemexpress LLC Platicodigenin | 22327-82-8 | 520.70 | 5 MG
SDP

Platicodigenin is a compound isolated from the plant *Platycodon grandiflorum*.

  • Isolated from *Platycodon grandiflorum*

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2

Medchemexpress LLC HIF-2α-IN-2 | 1672666-82-8 | 99.9% | 50 MG
SDP

HIF-2α-IN-2 is an inhibitor of hypoxia-inducible factors (HIF-2α), with an IC50 of 16 nM in a scintillation proximity assay (SPA). It was originally extracted from patent WO2015035223A1 (Compound 232).

  • Inhibits hypoxia-inducible factors (HIF-2α)
  • Features an IC50 of 16 nM in SPA
  • Molecular formula: C17H13F2NO4S
  • Molecular weight: 365.35
  • Appears as a white to off-white solid

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3

Medchemexpress LLC HIF-2α-IN-2 | 1672666-82-8 | 99.9% | C17H13F2NO4S | 10MG
SDP

HIF-2α-IN-2 is a small-molecule research reagent that inhibits hypoxia-inducible factor-2α (HIF-2α). Originally reported in patent literature, it is used in biochemical and cellular studies to probe HIF-2α function and related hypoxia responses. Supplied as a high-purity solid or as a ready-to-use DMSO solution for in vitro research.

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4

Medchemexpress LLC HY-110249 10mg Medchemexpress, CINPA1 CAS:102636-74-8 Purity:>98%
SDP

Medchemexpress, HY-110249 10mg CINPA1 CAS:102636-74-8 CINPA1 is a potent and specific inhibitor of constitutive androstane receptor (CAR) that does not activate pregnane X receptor (PXR). CINPA1 reduces CAR-mediated transcription with an IC50 of ~70 nM. CINPA1 can be used as a molecular tool for understanding CAR function. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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5

Medchemexpress LLC HY-15727A 5mg Medchemexpress, Afuresertib (hydrochloride) CAS:1047645-82-8 Purity:>98%
SDP

Medchemexpress, HY-15727A 5mg Afuresertib (hydrochloride) CAS:1047645-82-8 Afuresertib hydrochloride (GSK 2110183 hydrochloride) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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6

Medchemexpress LLC Zagociguat (CY-6463) | 2201048-82-8 | MFCD34676490 | 98.0% | 362.28 g/mol | C16H10F4N6 | 5 MG
SDP

Zagociguat is an orally active, blood-brain barrier-permeable soluble guanylate cyclase (sGC) stimulator used in research to elevate intracellular cGMP and investigate NO-sGC-cGMP signaling pathways. It is employed in preclinical and clinical research addressing neurodegeneration and mitochondrial disease and is supplied in small research pack sizes with defined storage conditions.

  • Orally active and brain-penetrant sGC stimulator.
  • Increases intracellular cGMP to modulate NO-sGC-cGMP signaling.
  • Applicable to neurodegeneration and mitochondrial disease research.
  • Provided in small research pack sizes suitable for laboratory studies.
  • Powder stable at -20°C for up to 3 years; solutions require low-temperature storage.

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7

eMolecules​ Medchem Express / Zagociguat / 5mg / 721309664 / HY-145607 / / 2201048-82-8 / [null] / 362.292 / C16H10F4N6

Medchem Express / Zagociguat / 5mg / 721309664 / HY-145607 / / 2201048-82-8 / [null] / 362.292 / C16H10F4N6

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8

eMolecules​ rel-(1R,2R)-2-(4-Fluorophenyl)cyclopropane-1-carboxylic acid | 175275-74-8 | | 1g

Synthonix - Stock | rel-(1R,2R)-2-(4-Fluorophenyl)cyclopropane-1-carboxylic acid | 1g | 499993435 | F61869 | | 175275-74-8 | | 180.178 | C10H9FO2

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9

Medchemexpress LLC 3h-cyclopenta[c]quinoline, 4-(5-bromo-2-methoxyphenyl)-8-fluoro-3a,4,5,9b-tetrahydro | 415919-74-3 | 98.6% | C19H17BrFNO | 10MG
SDP

GPR30 agonist-1 is a selective small-molecule agonist of G protein-coupled receptor 30 (GPR30/GPER) for receptor pharmacology and vascular biology research. It exhibits concentration-dependent vasorelaxant effects in preclinical assays and is supplied with analytical documentation suitable for research use.

  • Small-molecule agonist of G protein-coupled receptor 30 (GPR30/GPER).
  • Reported vasorelaxant activity in preclinical studies.
  • High purity (98.6%) suitable for biochemical and cellular assays.
  • Available as a solid or as a 10 mM solution in DMSO for ready-to-use experiments.
  • SDS and certificate of analysis provided for quality verification.
  • Molecular formula C19H17BrFNO; molecular weight 374.25 g/mol.

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