Methoxybenzoic acids and derivatives
Medchemexpress LLC Hydroxy-PEG4-acid 10g | 937188-59-5 | 10 G
Hydroxy-PEG4-acid is a four-unit polyethylene glycol (PEG) linker with a terminal hydroxyl and a carboxylic acid, supplied as a purified reagent for bioconjugation and linker synthesis. It is suitable for use as a non-cleavable spacer in antibody-drug conjugates (ADCs), and as a PEG-based linker in PROTACs and related chemistries.
- Four-unit PEG spacer with terminal hydroxyl and carboxylic acid.
- High purity suitable for research use.
- Available in multiple pack sizes, including 10 G.
- Stable when stored at recommended temperatures for long-term use.
- Useful for ADC linker construction, PROTAC assembly, and general bioconjugation.
Medchemexpress LLC Hydroxy-PEG1-acid 5g | 89211-34-7 | 5 G
Hydroxy-PEG1-acid is a single-unit polyethylene glycol (PEG1) linker with terminal hydroxyl and carboxylic acid groups. Supplied for research use as a non-cleavable ADC linker, it provides a short PEG spacer to improve solubility and spacing between an antibody and payload in antibody-drug conjugates.
- Non-cleavable single-unit PEG linker for ADC synthesis.
- Terminal hydroxyl and carboxylic acid functional groups for conjugation.
- Short PEG spacer to improve solubility and reduce aggregation.
- Typical purity around 95% and colorless to light yellow appearance.
- Available in small research pack sizes, including 5 G.
Medchemexpress LLC Hydroxy-PEG2-acid | 1334286-77-9 | 97.0% | 178.18 g/mol | C7H14O5 | 5G
Hydroxy-PEG2-acid is a hydroxyl-terminated polyethylene glycol (PEG) linker intended for use in the synthesis of proteolysis-targeting chimeras (PROTACs). It provides a short, flexible spacer to connect ligands for target binding and E3 ligase recruitment, supporting conjugation chemistry in chemical biology and early drug discovery workflows.
- Hydroxyl-terminated PEG2 linker
- Designed for PROTAC synthesis and conjugation chemistry
- CAS number 1334286-77-9
- Molecular weight 178.18 g/mol
- Chemical formula C7H14O5
- Purity 97.0%
- Available in multiple sizes from 100 mg to gram quantities
Medchemexpress LLC Methoxy-PEG-C3-amide-C2-Mal | 883993-35-9 | 2000 (average) | (C2H4O)nC11H16N2O4 | 10 MG
Methoxy-PEG-C3-amide-C2-Mal is a maleimide-activated methoxy polyethylene glycol (PEG) linker (average MW ~2,000 Da) used to conjugate PEG to thiol-containing biomolecules for site-selective PEGylation in research applications. Supplied as a solid powder and intended for research use only.
- Maleimide reacts selectively with thiol groups (e.g., cysteine) under mild conditions.
- Average molecular weight ~2,000 Da for improved solubility and steric shielding.
- Methoxy end cap minimizes non-specific interactions after conjugation.
- Supplied as a stable solid; store at recommended cold temperatures to preserve integrity.
- Available in small lab-scale pack sizes suitable for research workflows.
Medchemexpress LLC Hydroxy-PEG1-acid 10g | 89211-34-7 | 134.13 g/mol | C5H10O4 | 10 G
Hydroxy-PEG1-acid is a non-cleavable, single-unit polyethylene glycol (PEG) linker used as a short spacer in the synthesis of antibody-drug conjugates (ADCs). It has a terminal hydroxyl and carboxylic acid to enable common conjugation chemistries, is supplied as a purified research reagent (purity 95%), and is available in multiple pack sizes for laboratory use.
- Provides a non-cleavable, single-unit PEG spacer for ADC linkages.
- Terminal carboxylic acid enables standard amide coupling chemistries.
- Hydroxyl group permits additional functionalization options.
- High purity suitable for research applications (95%).
- Available in multiple pack sizes, including a 10 g package.