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Filtered Search Results
Medchemexpress LLC HY-14885 100mg , Eliglustat Genz 99067 CAS:491833-29-5 Purity:98%
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Medchemexpress, HY-14885 100mg Eliglustat Genz 99067 CAS:491833-29-5 Formula:C23H36N2O4 IC50: 24 nM (glucocerebroside synthase) Purity:98% Eliglustat is an specific, potent and orally active glucocerebroside synthase inhibitor with an IC 50 of 24 nM. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-112642 10mg Medchemexpress, 9-Methoxycanthin-6-one CAS:74991-91-6 Purity:>98%
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Medchemexpress, HY-112642 10mg 9-Methoxycanthin-6-one CAS:74991-91-6 9-Methoxycanthin-6-one, a canthin-6-one alkaloid, is present in intact plant parts and in callus tissues of different explants. 9-Methoxycanthin-6-one shows anti-tumor activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 4,5-Difluoropyridin-2-amine | 1211537-08-4 | MFCD18259315 | 100mg
Ambeed | 4,5-Difluoropyridin-2-amine | 100mg | 600836413 | A285279 | | 1211537-08-4 | MFCD18259315 | 130.098 | C5H4F2N2
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Medchemexpress LLC Phenoxybenzamine hydrochloride | 63-92-3 | 99.5% | 1 G
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Phenoxybenzamine hydrochloride is a nonselective, irreversible, orally active α-adrenoceptor antagonist. It is primarily used in research for hypertension, particularly that caused by pheochromocytoma, and has also demonstrated antitumor activity.
- Inhibits proliferation of U251 and U87MG cells.
- Inhibits migration and invasion of U251 and U87MG cells.
- Activates LINGO-1 and inhibits the TrkB-Akt pathway.
- Prevents hippocampal cell death after oxygen glucose deprivation.
- Demonstrates anti-tumorigenic effect in nude mice with U87MG tumors.
- Exhibits neuroprotective properties in a rat model of severe traumatic brain injury.
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Medchemexpress LLC BAY-293 10mg | 2244904-70-7 | 10 MG
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BAY-293 is a small-molecule chemical probe that inhibits the SOS1-KRAS interaction, reducing RAS activation (reported IC50 ≈ 21 nM). Supplied as a purified solid for research use; store at -20°C.
- Potent SOS1-KRAS interaction inhibitor (IC50 ≈ 21 nM).
- High purity, ≥98% by HPLC.
- Molecular weight 448.59 g·mol⁻1.
- Chemical formula C25H28N4O2S.
- Supplied as a milligram-scale solid; store at -20°C.
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Sigma Aldrich Fine Chemicals Biosciences 14 Dimethoxybenzene 99 fG
1 4-Dimethoxybenzene can be used as a flavoring agent in the food industry. It s one of the main volatile constituents identified inTuber brumale Vietnamese green tea and lotus tea.
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Sigma Aldrich Fine Chemicals Biosciences Pindolol >=98% (TLC), powder | 13523-86-9 | MFCD00010530 | 250MG
Pindolol >=98% (TLC), powder | Purity: >=98% (TLC) | Mol Wt: 248.32 | 13523-86-9 | MFCD00010530 | 250MG
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Medchemexpress LLC Hxr9 hydrochloride | 99.5% | 2754.67 | 10 MG
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HXR9 hydrochloride is a cell-permeable peptide and a competitive antagonist of HOX/PBX interaction. It works by antagonizing the interaction between HOX and PBX, a transcription factor that binds to HOX proteins in paralogue groups 1 to 8. This compound selectively decreases cell proliferation and promotes apoptosis in cells that highly express HOXA/PBX3 genes, such as MLL-rearranged leukemic cells.
- Cell-permeable peptide
- Competitive antagonist of HOX/PBX interaction
- Decreases cell proliferation
- Promotes apoptosis
- Blocks tumor growth in vivo
- Causes specific transcriptional changes
- Potential therapeutic target
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Medchemexpress LLC Tivozanib hydrochloride hydrate | 682745-41-1 | 99.8% | 509.34 | 10 MG
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Tivozanib hydrochloride hydrate is the hydrate hydrochloride form of Tivozanib. It is a selective, orally active inhibitor for vascular endothelial growth factor receptor (VEGFR)-1, 2, and 3, with IC50s of 30, 6.5, and 15 nM, respectively. It exhibits antitumor efficacy.
- Selective, orally active inhibitor for VEGFR-1, 2, and 3.
- Exhibits antitumor efficacy.
- Inhibits the phosphorylation of VEGFR-1, VEGFR-2, and VEGFR-3.
- Inhibits VEGF-induced proliferation and migration of HUVECs.
- Selectively inhibits VEGF-stimulated phosphorylation of MAPKs in endothelial cells.
- Exhibits antitumor efficacy against various cancers in athymic mice models.
- Reversibly suppresses vascular permeability and angiogenesis.
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eMolecules (3-(2-Fluoroethoxy)phenyl)boronic acid | 2096332-11-3 | MFCD18783120 | 1g
Ambeed | (3-(2-Fluoroethoxy)phenyl)boronic acid | 1g | 601095815 | A354171 | | 2096332-11-3 | MFCD18783120 | 183.970 | C8H10BFO3
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eMolecules AstaTech / 4-(BENZYLOXY)BENZONITRILE / 5g / 248485000 / AB6270 / 95.000 / 52805-36-4 / MFCD00079701 / 209.248 / C14H11NO
AstaTech / 4-(BENZYLOXY)BENZONITRILE / 5g / 248485000 / AB6270 / 95.000 / 52805-36-4 / MFCD00079701 / 209.248 / C14H11NO
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Medchemexpress LLC HY-120056 10mg Medchemexpress, YKL-06-061 CAS:2172617-15-9 Purity:>98%
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Medchemexpress, HY-120056 10mg YKL-06-061 CAS:2172617-15-9 YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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![eMolecules Medchem Express / BMS641 / 5mg / 769193238 / HY-119518 / / 369364-50-1 / [null] / 414.930 / C27H23ClO2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502473828.JPG-250.jpg)
eMolecules Medchem Express / BMS641 / 5mg / 769193238 / HY-119518 / / 369364-50-1 / [null] / 414.930 / C27H23ClO2
Medchem Express / BMS641 / 5mg / 769193238 / HY-119518 / / 369364-50-1 / [null] / 414.930 / C27H23ClO2
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Medchemexpress LLC Tubulin inhibitor 6 (compound 14b) | 105925-39-1 | 99.0% | C20H14ClNO2S | 10MG
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Tubulin inhibitor 6 is a small-molecule tubulin polymerization inhibitor (Compound 14b) used for preclinical research. It has molecular formula C20H14ClNO2S, molecular weight 367.85 g/mol, CAS 105925-39-1, and shows activity against tubulin (IC50 = 0.87 μM) and K562 cell growth (IC50 = 840 nM).
- Inhibits tubulin polymerization (IC50 = 0.87 μM).
- Reduces K562 cell growth (IC50 = 840 nM).
- High reported purity (99.0%).
- Available in small-mass quantities suitable for screening and assay development.
- Characterized by molecular formula C20H14ClNO2S and molecular weight 367.85 g/mol.
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Medchemexpress LLC HY-112610 10mg Medchemexpress, CF53 CAS:1808160-52-2 Purity:>98%
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Medchemexpress, HY-112610 10mg CF53 CAS:1808160-52-2 CF53 is a highly potent, selective and orally active inhibitor of BET protein, with a Ki of <1 nM, Kd of 2.2 nM and an IC50 of 2 nM for BRD4 BD1. CF53 binds to both the BD1 and BD2 domains of BRD2, BRD3, BRD4, and BRDT BET proteins with high affinities, very selective over non-BET bromodomain-containing proteins. CF53 shows potent anti-tumor activity both in vitro and in vivo. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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