Phenoxy compounds

Medchemexpress LLC 4H-1-Benzopyran-4-one, 6-methoxy-5-nitro-2-(trifluoromethyl)- | 342795-08-8 | 99.85% | 289.16 | 50 MG

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Bragsin2 is a potent, selective, and noncompetitive nucleotide exchange factor BRAG2 inhibitor with an IC50 of 3 μM. It binds at the interface between the PH domain of BRAG2 and the lipid bilayer, preventing activation of lipidated Arf GTPase. This compound affects breast cancer stem cells.

• Potent, selective, and noncompetitive nucleotide exchange factor BRAG2 inhibitor with an IC50 of 3 μM.
• Binds at the interface between the PH domain of BRAG2 and the lipid bilayer.
• Leads to BRAG2 being unable to activate lipidated Arf GTPase.
• Affects breast cancer stem cells.
• Inhibits Arf GTPase activation in HeLa cells at 50 μM.
• Inhibits the growth of SUM149 and S68 cells at 50 μM.

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eMolecules​ 938-73-8 | 2-Ethoxybenzamide | Oakwood Chemicals | MFCD00007977 | 165.192 | C9H11NO2 | 97.000 | CCOc1ccccc1C(N)=O | 5g | 480149412

2-Ethoxybenzamide | Oakwood Chemicals | 938-73-8 | MFCD00007977 | 165.192 | C9H11NO2 | 97.000 | CCOc1ccccc1C(N)=O | 5g | 480149412

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Medchemexpress LLC HY-15801 5mg Medchemexpress, HG-14-10-04 CAS:1356962-34-9 Purity:>98%

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Medchemexpress, HY-15801 5mg HG-14-10-04 CAS:1356962-34-9 HG-14-10-04 (example 10) is a potent and specific ALK inhibitor with an IC50 of 20 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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Medchemexpress LLC Trimetazidine | 5011-34-7 | 99.8% | 266.34 g/mol | C14H22N2O3 | 10 MG

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Trimetazidine is a small-molecule antianginal and cytoprotective research compound that modulates fatty acid metabolism and autophagy. It inhibits long-chain 3-ketoyl coenzyme A thiolase, reduces β-oxidation of free fatty acids, and has reported antioxidant and anti-inflammatory activities. Intended for laboratory research use only; not for human or clinical use.

• Research-grade small molecule for laboratory studies.
• Inhibits long-chain 3-ketoyl CoA thiolase and modulates fatty acid metabolism.
• Exhibits antioxidant, anti-inflammatory, and cytoprotective properties.
• Molecular formula C14H22N2O3; molecular weight 266.34 g/mol.
• Supplied as a 10 MG quantity suitable for experimental dosing and formulation.

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Sigma Aldrich Fine Chemicals Biosciences 13 Dimethoxybenzene 98 fG5KG

1 3-Dimethoxybenzene can be used as a flavoring agent in the food industry. It is reported to be found in the volatiles of port wine and Roquefort cheese.

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Medchemexpress LLC Hxr9 hydrochloride | 99.5% | 2754.67 | 10 MG

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HXR9 hydrochloride is a cell-permeable peptide and a competitive antagonist of HOX/PBX interaction. It works by antagonizing the interaction between HOX and PBX, a transcription factor that binds to HOX proteins in paralogue groups 1 to 8. This compound selectively decreases cell proliferation and promotes apoptosis in cells that highly express HOXA/PBX3 genes, such as MLL-rearranged leukemic cells.

• Cell-permeable peptide
• Competitive antagonist of HOX/PBX interaction
• Decreases cell proliferation
• Promotes apoptosis
• Blocks tumor growth in vivo
• Causes specific transcriptional changes
• Potential therapeutic target

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eMolecules​ 110534-79-7 | N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-4-methylbenzamide | Oakwood Chemicals | MFCD00863108 | 396.470 | C20H20N4O3S | 96.000 | Cc1ccc(cc1)C(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nc(C)cc(C)n1 | 10mg | 480151964