Phenylhydrazines
Aobchem (3-Cyano-2-fluoro-5-methylphenyl)boronic acid | ≥95% | CAS 1801916-87-9 | C8H7BFNO2 | 500mg
(3-Cyano-2-fluoro-5-methylphenyl)boronic acid | ≥95% | CAS 1801916-87-9 | C8H7BFNO2 | 500mg
![Medchemexpress LLC 2,4-Pyrimidinediamine, N2-[4-[(3-aminopropyl)amino]phenyl]-N4-(5-cyclopropyl-1H-pyrazol-3-yl)- | 2700435-52-3 | 99.5% | 400.91 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000388166-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2,4-Pyrimidinediamine, N2-[4-[(3-aminopropyl)amino]phenyl]-N4-(5-cyclopropyl-1H-pyrazol-3-yl)- | 2700435-52-3 | 99.5% | 400.91 | 1 ML
VEGFR-2-IN-5 hydrochloride is a potent inhibitor of VEGFR2, appearing as an off-white to light yellow solid. It is designed for research applications.
- Purity: 99.51% (LCMS)
- Molecular formula: C19H25ClN8
- Molecular weight: 400.91
- Store powder at 4°C under nitrogen or at -20°C for up to 3 years.
- Store in solvent at -80°C for up to 6 months or at -20°C for up to 1 month.
- Research use only.
- Referenced in patent WO2013055780A1.
Medchemexpress LLC AG-636 | 1623416-31-8 | 98.1% | 343.38 | 5 MG
AG-636 is a potent, reversible, selective, and orally active dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 17 nM. It demonstrates strong anticancer effects.
- Exhibits strong growth-inhibitory activity in cancer cell lines of both hematologic and solid tumor origin.
- Functions as a dihydroorotate dehydrogenase (DHODH) inhibitor.
- Applications:
- In vitro: has shown strong growth-inhibitory activity in various cancer cell lines.
- In vivo: treatment resulted in robust tumor growth inhibition in the OCILY19 DLBCL tumor xenograft model.
- Clinical trials: being investigated in a Phase 1 clinical trial (NCT03834584) for lymphoma, which started on May 24, 2019.
Medchemexpress LLC Diclofensine (hydrochloride) | 34041-84-4 | 99.79% | 358.69 | 1 ML
Diclofensine hydrochloride is an orally active neuronal monoamine uptake inhibitor. It blocks the uptake of dopamine, noradrenaline, and serotonin, and can be used in the research of moderate to severe depression.
- Orally active neuronal monoamine uptake inhibitor.
- Blocks dopamine, noradrenaline, and serotonin uptake.
- Potentiates norepinephrine-induced hypertension.
- Attenuates Tyramine-induced hypertension.
- Produces psychostimulant and mood-elevating effects.
- Can be used in research of moderate to severe depression.
Medchemexpress LLC Cloperastine hydrochloride | 14984-68-0 | 99.4% | 1 ML
Cloperastine hydrochloride | 14984-68-0 | 99.4% | 1 ML
Medchemexpress LLC Bendamustine hydrochloride | 3543-75-7 | 99.9% | C16H22Cl3N3O2 | 50 MG
Bendamustine hydrochloride is a purine analogue and a DNA cross-linking agent. It activates DNA-damage stress response and apoptosis, possessing potent alkylating, anticancer, and antimetabolite properties. This product is for research use only.
- Purine analogue
- DNA cross-linking agent
- Activates DNA-damage stress response and apoptosis
- Possesses potent alkylating, anticancer, and antimetabolite properties
- Induces caspase-dependent MM cell death
- Inhibits the spindle-assembly checkpoint
Medchemexpress LLC Itacnosertib (hydrochloride) | 2409543-84-4 | 99.4% | 505.01 | 50 MG
Itacnosertib hydrochloride (TP-0184 hydrochloride) is an inhibitor for FLT3, ACVR1, and JAK2. It exhibits anti-leukemic activity and is intended for research use only. This compound has shown promising results in pre-clinical studies, demonstrating its potential in various biological applications.
- Inhibits FLT3, ACVR1 (ALK2), and JAK2
- Exhibits anti-leukemic activity
- Arrests cell cycle of MOLM-13, MOLM-14, and MV4-11 at G1/G0 phase
- Inhibits proliferation of acute myeloid leukemia (AML) cells
- Inhibits activation of FLT3 and ACVR1 downstream signaling pathways
- Shows antitumor activity in mouse xenograft models
