Phenylhydrazines
Medchemexpress LLC Proparacaine hydrochloride | 5875-06-9 | 99.9% | C16H27ClN2O3 | 1 ML
Proparacaine hydrochloride, also known as Proxymetacaine hydrochloride, is a derivative of lidocaine. It exhibits immunomodulatory and glucocorticomimetic activity. This product is intended for research use only.
- Exhibits dose- and time-dependent cytotoxicity to HCS cells
- Induces apoptosis of HCS cells
- Induces G1 phase arrest
- Activates caspase-2, -3, and -9
- Modulates Bcl-xL and Bax expression
- Reduces nasal symptoms and inflammation in allergic rhinitis mouse models
Medchemexpress LLC Pyridostatin hydrochloride | 1781882-65-2 | C31H37Cl5N8O5 | 1 ML
Pyridostatin hydrochloride | 1781882-65-2 | C31H37Cl5N8O5 | 1 ML
Medchemexpress LLC Almonertinib hydrochloride | 2134096-03-8 | 98.9% | 562.11 | 1 ML
Almonertinib hydrochloride is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. It shows great inhibitory activity against T790M, T790M/L858R and T790M/Del19, and is less effective against wild type. Almonertinib hydrochloride is used for the research of non-small cell lung cancer. It can also inhibit other EGFR sensitive mutations, including G719X, del19, L858R and L861Q.
- Orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor.
- High selectivity for EGFR-sensitizing and T790M resistance mutations.
- Great inhibitory activity against T790M, T790M/L858R and T790M/Del19.
- Less effective against wild-type EGFR.
- Used for research of non-small cell lung cancer.
- Inhibits other EGFR sensitive mutations such as G719X, del19, L858R and L861Q.