Aminophenols
Medchemexpress LLC Ozanimod hydrochloride | 1618636-37-5 | 98.1% | 10 MG
Ozanimod hydrochloride is the hydrochloride salt of ozanimod (RPC-1063), a selective sphingosine 1-phosphate (S1P) receptor modulator supplied for laboratory research use only. It is used in studies of immune modulation and relapsing multiple sclerosis.
- Purity 98.1%.
- Molecular weight 440.92.
- Molecular formula C23H25ClN4O3.
- White to off-white solid; also available as 10 mM solution in DMSO.
- Storage: 4°C sealed; in solvent: -80°C (6 months), -20°C (1 month).
- Intended for laboratory research on S1P receptor biology and multiple sclerosis models.
TARGETMOL CHEMICALS INC L-Azidohomoalanine hydrochlori
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 200 mg and bulk. Please contact Fisher for quotes. L-Azidohomoalanine hydrochloride (H-L-Aha-OH hydrochloride) is an alkyl chain-based PROTAC linker. Purity 98.16%
TARGETMOL CHEMICALS INC 3-Methoxytyramine hydrochlorid
Also available in 1 mL, 100 mg, 250 mg, 500 mg and bulk. Please contact Fisher for quotes. 3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride) is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1). 3-methoxytyramine can be found primarily in human brain and most tissues tissues; and in blood, cerebrospinal fluid (csf) or urine. Within a cell, 3-methoxytyramine is primarily located in the cytoplasm. Purity 98.99%
Medchemexpress LLC Tacrine hydrochloride | 1684-40-8 | 99.9% | 1 ML
Tacrine hydrochloride is a potent brain-penetrant inhibitor of both AChE and BChE. It also acts as an NMDAR inhibitor. This compound can be utilized in research related to Alzheimer's disease.
- Potent brain-penetrant inhibitor of AChE and BChE.
- NMDAR inhibitor.
- Used for Alzheimer's disease research.
- Appearance: Solid, white to light yellow.
- Shipping: Room temperature in continental US.
- Storage: 4°C, stored under nitrogen, away from moisture.
- In solvent storage: -80°C for 6 months; -20°C for 1 month (stored under nitrogen, away from moisture).
- Solubility in H2O: 33.33 mg/mL (141.99 mM; needs ultrasonic).
Chemscene ChemScene | 2,3-Diaminophenol | 10G | CS-W005863 | 0.97 | 59649-56-8| MFCD00075199 | 124.14
ChemScene | 2,3-Diaminophenol | 10G | CS-W005863 | 0.97 | 59649-56-8| MFCD00075199 | 124.14
Selleck Chemical LLC OTS514 hydrochloride-2mg
OTS514 is a highly potent TOPK(T-LAK cell-originated protein kinase) inhibitor with an IC50 value of 2.6 nM. OTS514 induces cell cycle arrest and apoptosis.
Medchemexpress LLC MT-7716 hydrochloride | 1215859-93-0 | 99.1% | 477.0 | C27H29ClN4O2 | 1 ML
MT-7716 hydrochloride is the hydrochloride salt of a selective non-peptide nociceptin (NOP) receptor agonist used for preclinical pharmacology research. It is supplied at high purity and is offered both as a ready-to-use DMSO solution and as solid quantities for formulation and biological testing. The compound is commonly used in studies of alcohol dependence, withdrawal, and relapse mechanisms.
Medchemexpress LLC Rgx-104 hydrochloride | 610318-03-1 | 99.9% | 632.54 | 1 MG
RGX-104 hydrochloride is a small-molecule LXR agonist that modulates innate immunity via transcriptional activation of the ApoE gene. It significantly suppresses the growth of multiple cancer types in animals, including lung cancer, melanoma, glioblastoma, ovarian, renal cell, triple-negative breast, and colon cancer, with some instances showing partial or complete tumor regression.
- Small-molecule LXR agonist.
- Modulates innate immunity via transcriptional activation of the ApoE gene.
- Significantly suppresses the growth of multiple cancer types in animals.
- Treatment causes partial or complete tumor regression in some instances.
- Available in solid form and in solution.
Medchemexpress LLC Rhosin hydrochloride | 1281870-42-5 | 99.9% | 394.86 | 100 MG
Rhosin hydrochloride is a potent and specific inhibitor of the RhoA subfamily of Rho GTPases. It specifically binds to RhoA to inhibit RhoA-GEF interaction and does not interact with Cdc42 or Rac1. This compound induces cell apoptosis and promotes stress resiliency by enhancing D1-MSN plasticity and reducing hyperexcitability.
- Potent and specific RhoA subfamily Rho GTPases inhibitor
- Induces cell apoptosis
- Promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability
- Dose-dependently reduces RhoA and p-MLC1 activities of mammospheres
- Decreases size and reduces number of mammospheres in cells
- Prevents social avoidance and blocks sucrose preference deficits in mice
- Attenuates stress-induced social avoidance
- Blocks stress-induced hyperexcitability in NAc dopamine 1 receptor medium spiny neurons (D1-MSNs)
Cayman Chemical N-acetyl-2-AmInophenol 250g
A derivative of acetaminophen; inhibits ADP- or arachidonic acid-induced platelet aggregation in isolated human platelet-rich plasma at 50 µM; decreases disease severity and prevents increases in paw volume in a rat model of collagen-induced arthritis at 1 mg/kg; has been used as a synthetic intermediate in the synthesis of compounds with antimalarial activity; a potential impurity in commercial preparations of acetaminophen
Medchemexpress LLC Afm32a hydrochloride | 2988594-85-8 | 99.7% | 517.00 g/mol | C25H30ClFN6O3 | 5 MG
AFM32a hydrochloride is a benzimidazole-derived small-molecule inhibitor selective for protein arginine deiminase 2 (PAD2). Supplied as the hydrochloride salt for research use, it is suitable for biochemical assays and target validation, demonstrating approximately 95-fold selectivity for PAD2 versus PAD4 and 79-fold versus PAD3.
- Potent PAD2 inhibition with high selectivity over PAD3 and PAD4.
- Hydrochloride salt form for improved solubility and handling.
- High purity (≈99.7%) appropriate for biochemical assays.
- Available in small-mass and DMSO solution formats for screening.
- Characterized with molecular formula and molecular weight for analytical use.
Medchemexpress LLC Pirmenol hydrochloride | 61477-94-9 | MFCD01691662 | 98.8% | 374.95 g·mol⁻¹ | C22H31ClN2O | 100 MG
Pirmenol hydrochloride is an orally active antiarrhythmic research compound used in pharmacology and electrophysiology studies. It inhibits IK.ACh currents by blocking muscarinic acetylcholine receptors and is provided as a high-purity solid for laboratory research use.
- Orally active compound suitable for cellular and in vivo studies.
- Reported to inhibit IK.ACh with IC50 ≈ 0.1 μM.
- High purity solid for reproducible experimental results.
- Available in small-quantity packages appropriate for research workflows.
- Intended for laboratory research; not for human or diagnostic use.
Medchemexpress LLC CC-115 hydrochloride | 1300118-55-1 | 98.01% | 372.81 | 1 ML
CC-115 hydrochloride is a potent, dual DNA-PK and mTOR kinase inhibitor. It targets both mTORC1 and mTORC2 signaling, making it a valuable tool for research applications. This compound has demonstrated significant inhibitory effects against PC-3 cell proliferation and exhibits good in vivo pharmacokinetic profiles, including high oral bioavailability in various animal models.
- Potent DNA-PK inhibitor (IC50 of 13 nM)
- Potent mTOR kinase inhibitor (IC50 of 21 nM)
- Blocks both mTORC1 and mTORC2 signaling
- Inhibits PC-3 cell proliferation with an IC50 of 138 nM
- Exhibits good in vivo pharmacokinetic profiles
- Demonstrates high oral bioavailability in mouse, rat, and dog
- Sustains inhibition through 24 hours
- Shows tumor volume reductions in vivo studies
Medchemexpress LLC Dc-chol hydrochloride | 166023-21-8 | 99.9% | 537.26 | 50 MG
DC-Chol hydrochloride is a cationic lipid that can inhibit Aβ40 fibril formation and amyloidogenesis. It enhances the body's immune response by inducing Th1 (IL-2 and IFN-γ) and Th2 (IL-5) cytokines, making it suitable for various research applications.
- Inhibits Aβ40 fibril formation and amyloidogenesis.
- Induces Th1 and Th2 cytokine production to enhance immune response.
- Used as a gene delivery vector.
- Utilized in research for hepatitis B vaccines to improve vaccine immunity.