Aminophenols
Medchemexpress LLC CX-6258 hydrochloride hydrate | 1353858-99-7 | 99.2% | 516.42 | 1 ML
CX-6258 hydrochloride hydrate is a potent and kinase selective pan-Pim kinases inhibitor, with IC50s of 5 nM, 25 nM and 16 nM for Pim-1, Pim-2 and Pim-3, respectively.
- Potent and kinase selective pan-Pim kinases inhibitor
- IC50s of 5 nM (Pim-1), 25 nM (Pim-2), 16 nM (Pim-3)
- Causes dose-dependent inhibition of the phosphorylation of pro-survival proteins Bad and 4E-BP1 at specific Pim kinase sites (S112, S65, T37/46)
- Diminishes steady-state levels and reduces half-life of ectopic NKX3.1 in PC3 cells
- Exhibits robust in vivo efficacy in two Pim kinases driven tumor models (e.g., MV-4-11 xenograft models in nude mice)
![Medchemexpress LLC 4-pyridinecarboxylic acid, 2-[[[2-[[2-(dimethylamino)ethyl]...]]-, hydrochloride | 3026728-26-4 | 96.6% | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000231786.png-250.jpg)
Medchemexpress LLC 4-pyridinecarboxylic acid, 2-[[[2-[[2-(dimethylamino)ethyl]...]]-, hydrochloride | 3026728-26-4 | 96.6% | 25 MG
KDM5-C49 hydrochloride is a potent, selective inhibitor of KDM5 histone demethylases used for biochemical and cellular research, including cancer studies. It is supplied as a high-purity solid-liquid mixture with defined storage recommendations to maintain stability.
- Potent KDM5 inhibitor with reported IC50s of 40 nM (KDM5A), 160 nM (KDM5B), and 100 nM (KDM5C).
- High purity suitable for research applications.
- Molecular weight approximately 344.84 g/mol.
- Physical form: solid-liquid mixture, colorless to light yellow.
- Recommended storage: 4°C sealed; stock solutions: -80°C (up to 6 months) or -20°C (up to 1 month).
- Available in small milligram pack sizes for laboratory use.
Medchemexpress LLC RS 67333 (hydrochloride) | 168986-60-5 | MFCD00938576 | 99.7% | 389.36 | C19H30Cl2N2O2 | 25 MG
RS 67333 hydrochloride is a research-grade, selective 5-HT4 receptor partial agonist used in preclinical and in vitro neuroscience studies to investigate serotonergic signaling and neuroprotective mechanisms.
- Potent, selective 5-HT4 receptor partial agonist for neuroscience research.
- High purity, 99.7% (as listed by manufacturer).
- Molecular weight 389.36 g/mol; formula C19H30Cl2N2O2.
- Solid, light yellow to yellow appearance supplied as a dry powder.
- Storage: 4°C, sealed and away from moisture; in solvent store at -80°C for long-term.
- Available as a 25 MG vial for laboratory use.
- CAS number 168986-60-5.
Medchemexpress LLC Prilocaine-d7 hydrochloride | 98.2% | 500 UG
Prilocaine-d7 hydrochloride is a deuterium-labeled form of Prilocaine hydrochloride, an amino amide and a Na, K-ATPase inhibitor. Known to have neurotoxic effects, this compound is for research use only and not sold to patients. Its deuterated nature can impact pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis via NMR, GC-MS, or LC-MS
Medchemexpress LLC CGP71683 hydrochloride | 192322-50-2 | MFCD07783999 | 99.4% | 512.07 g/mol | C26H30ClN5O2S | 1 ML
CGP71683 hydrochloride is a selective, non-peptide neuropeptide Y (NPY) Y5 receptor antagonist (Ki = 1.3 nM) commonly used in receptor pharmacology and signaling research. It demonstrates substantially reduced activity at Y1 and Y2 receptors and is supplied both as a solid and as a pre-made DMSO solution for ready-to-use assays.
- Selective NPY Y5 receptor antagonist (Ki = 1.3 nM).
- High selectivity over Y1 and Y2 receptors.
- Available as solid or 10 mM solution in DMSO, 1 mL.
- High purity suitable for research applications.
- Intended for receptor pharmacology and signaling studies.
Medchemexpress LLC CSRM617 hydrochloride | 1353749-74-2 | 100.0% | 5MG
CSRM617 hydrochloride | 1353749-74-2 | 100.0% | 5MG