Aminophenols
Aobchem 2-Chloroethanamine hydrochloride | ≥95% | CAS 870-24-6 | C2H7Cl2N | 500g
2-Chloroethanamine hydrochloride | ≥95% | CAS 870-24-6 | C2H7Cl2N | 500g
Medchemexpress LLC Bepridil hydrochloride | 68099-86-5 | MFCD00065498 | 99.8% | 403.0 g/mol | C24H35ClN2O | 25 MG
Bepridil hydrochloride is a non-selective calcium channel blocker with antianginal activity, commonly used in cardiovascular and ion channel research to study calcium-mediated cardiac effects. The compound is provided as the hydrochloride salt (CAS 68099-86-5) with molecular formula C24H35ClN2O and molecular weight 403.0 g/mol.
- Non-selective calcium channel blocker used in cardiac and ion channel studies.
- Useful for investigating calcium-dependent electrophysiology and myocardial contractility.
- Hydrochloride salt form enhances solubility for assay preparation.
- Intended for in vitro and ex vivo research applications.
- Well-characterized chemical identifiers: CAS 68099-86-5; molecular formula C24H35ClN2O; molecular weight 403.0 g/mol.
Medchemexpress LLC Acetaminophen-d7 | 1219798-53-4 | 99.9% | C8H2D7NO2 | 1 MG
Acetaminophen-d7 is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; it is a widely used antipyretic and analgesic agent and a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Daurk-4 (hydrochloride) | 99.44% | 1071.93 | 25 MG
dAURK-4 hydrochloride, an Alisertib derivative, is a potent and selective PROTAC AURKA (Aurora A) degrader with anticancer effects. It is composed of a ligand for the target protein, a linker, and a ligand for E3 ligase Thalidomide-O-COOH.
- Potent and selective PROTAC AURKA degrader
- Demonstrates dose-dependent degradation of AURKA
- Inhibits protein level of AURKA in MM.1S cells
- Composed of a ligand for the target protein, a linker, and a ligand for E3 ligase
Medchemexpress LLC AT7519 Hydrochloride | 902135-91-5 | 99.2% | C16H18Cl3N5O2 | 100 MG
AT7519 Hydrochloride is a potent inhibitor of Cyclin-Dependent Kinases (CDKs), exhibiting strong inhibitory activity against CDK1, CDK2, CDK4 to CDK6, and CDK9. It induces dose-dependent cytotoxicity and apoptosis in MM cells and inhibits cell cycle progression in various human tumor cell lines. In preclinical studies, AT7519 Hydrochloride effectively inhibits tumor growth in both human MM and HCT116 xenograft mouse models.
- Potent inhibitor of CDKs (IC50 values range from <10 nM to 210 nM)
- Induces cytotoxicity and apoptosis in MM cells
- Overcomes cytokine and BMSC protective effects
- Inhibits RNA polymerase II CTD phosphorylation and RNA synthesis
- Inhibits cell cycle progression and induces apoptosis in tumor cell lines
- Reduces antiapoptotic protein levels
- Inhibits tumor growth in MM and HCT116 xenograft models
![eMolecules 86347-15-1 | Medetomidine Hydrochloride | Key Organics/BIONET236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 8mg | 564356417](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000127953.jpg-250.jpg)
eMolecules 86347-15-1 | Medetomidine Hydrochloride | Key Organics/BIONET236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 8mg | 564356417
Medetomidine Hydrochloride | Key Organics/BIONET | 86347-15-1236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 8mg | 564356417
Medchemexpress LLC A-350619 hydrochloride | 1217201-17-6 | ≥99.0% | 425.41 g/mol | C21H25ClN2OS·HCl | 10 MG
A-350619 hydrochloride is a small-molecule soluble guanylate cyclase (sGC) activator used in preclinical research. It enhances cGMP production by activating basal sGC and synergizing with nitric oxide, producing vasodilatory effects such as cavernosum smooth muscle relaxation and increased blood flow in animal models. The material is supplied as a hydrochloride salt for improved solubility.
- High purity suitable for in vitro and in vivo studies.
- Soluble hydrochloride salt with good DMSO and aqueous solubility.
- Activates soluble guanylate cyclase and enhances NO-mediated signaling.
- Demonstrated vasodilatory and penile erection effects in rodent models.
- Store at 4°C to maintain stability.
eMolecules 5325-64-4 | Sarcosine amide hydrochloride | Chem-Impex | MFCD00058283 | 124.570 | C3H9ClN2O | 99.000 | Cl.CNCC(N)=O | 1g | 112449205
Sarcosine amide hydrochloride | Chem-Impex | 5325-64-4 | MFCD00058283 | 124.570 | C3H9ClN2O | 99.000 | Cl.CNCC(N)=O | 1g | 112449205
Medchemexpress LLC HAIYPRH hydrochloride | 99.97% | 929.46 | 50 MG
HAIYPRH hydrochloride is a targeting ligand that specifically binds to the transferrin receptor (TfR), facilitating the transport of nanocarriers across the blood-brain barrier. It is a heptapeptide investigated for targeting gliomas and enhancing cellular uptake and gene expression in co-delivery systems.
- Specifically binds to transferrin receptor (TfR).
- Mediates transport of nanocarriers across the blood-brain barrier.
- Utilized as a targeting agent for gliomas.
- Enhances cellular uptake and gene expression in co-delivery systems.
- Conjugated to liposomes for ischemic stroke targeting treatment.
Medchemexpress LLC S-14506 hydrochloride | 286369-38-8 | 99.92% | 443.94 | 100 MG
S-14506 hydrochloride is a potent 5-HT1A agonist and a 5-HT2A/2C antagonist. It also exhibits dopamine antagonist properties by blocking dopamine D2 receptors, inhibiting the in vivo binding of [3H]raclopride in striatum and olfactory bulbs. This compound has potential for research as an anxiolytic agent.
- Potent 5-HT1A agonist
- 5-HT2A/2C antagonist
- Exhibits dopamine D2 receptor blocking properties
- Potential for research as an anxiolytic agent
Medchemexpress LLC SKI-I 10mg | 306301-68-8 | 406.44 | C25H18N4O2 | 10 MG
SKI-I is a small-molecule sphingosine kinase inhibitor supplied as a 10 mg research-grade solid for laboratory use. It inhibits human sphingosine kinase with reported IC50 ≈ 1.2 μM and shows additional activity against hERK2; reported purity and storage conditions support reproducible experimental use.
- High reported purity (99.14%).
- Off-white to light yellow solid; convenient 10 mg quantity for assay development.
- Soluble in DMSO at 100 mg/mL; suitable for in vitro use and formulatable for in vivo studies.
- Storage: powder at 4°C protected from light; aliquots in solvent stable at -80°C for up to 6 months.
- Demonstrated cytotoxicity against multiple human cancer cell lines at low micromolar concentrations.
eMolecules 65646-68-6 | Fenretinide | Apollo Scientific | MFCD00792674 | 391.555 | C26H33NO2 | 99.000 | C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(=O)Nc1ccc(O)cc1 | 100mg | 562460510
Fenretinide | Apollo Scientific | 65646-68-6 | MFCD00792674 | 391.555 | C26H33NO2 | 99.000 | C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(=O)Nc1ccc(O)cc1 | 100mg | 562460510
eMolecules 202475-60-3 | JANEX-1 | AstaTech | MFCD01862614 | 297.314 | C16H15N3O3 | 95.000 | COc1cc2ncnc(Nc3ccc(O)cc3)c2cc1OC | 1g | 290663216
JANEX-1 | AstaTech | 202475-60-3 | MFCD01862614 | 297.314 | C16H15N3O3 | 95.000 | COc1cc2ncnc(Nc3ccc(O)cc3)c2cc1OC | 1g | 290663216