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Filtered Search Results
Medchemexpress LLC YIL781 hydrochloride | 1640226-17-0 | 99.5% | 445.96 g/mol | C24H29ClFN3O2 | 5 MG
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YIL781 hydrochloride is the hydrochloride salt of a potent, orally active ghrelin receptor (GHSR) antagonist used in preclinical research to study ghrelin signaling, metabolic regulation, and insulin secretion. The compound is provided with solubility guidance and storage recommendations for reliable use in experimental workflows.
- Potent ghrelin receptor (GHSR) antagonist suitable for pharmacological studies.
- Usable in vitro and in vivo applications.
- High purity (~99.5%) for reliable experimental results.
- Soluble in DMSO; formulation guidance provided for aqueous preparations.
- Stable when stored sealed at -20°C; solvent stability recommendations available.
- Available in small research pack sizes for early-stage studies.
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Medchemexpress LLC Cyclohexanecarboxylic acid, 1-phenyl-, 2-(4-morpholinyl)ethyl ester, hydrochloride (1:1) | 75136-54-8 | 99.8% | 353.88 | 1 ML
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PRE-084 hydrochloride is a highly selective σ1 receptor (S1R) agonist, with an IC50 of 44 nM. It exhibits good neuroprotective effects, can improve motor function and motor neuron survival in mice, and can ameliorate myocardial ischemia-reperfusion injury in rats by activating the Akt-eNOS pathway.
- Highly selective σ1 receptor (S1R) agonist (IC50 of 44 nM).
- Exhibits neuroprotective effects.
- Improves motor function and motor neuron survival in mice.
- Ameliorates myocardial ischemia-reperfusion injury in rats by activating the Akt-eNOS pathway.
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Medchemexpress LLC Acetaminophen glucuronide sodium salt | 120595-80-4 | MFCD00153898 | ≥99.0% | 349.27 g/mol | C14H16NNaO8 | 1 MG
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Acetaminophen glucuronide sodium salt is the sodium salt of the primary glucuronide metabolite of acetaminophen. Supplied as a white to off-white solid, it is used as a reference standard in analytical chemistry, metabolite identification, and toxicology research.
- Primary glucuronide metabolite of acetaminophen.
- Supplied as a white to off-white solid, soluble in water.
- Molecular formula C14H16NNaO8 and molecular weight 349.27 g/mol.
- High purity (≥99.0%).
- Available in small pack sizes for analytical use (1 mg, 5 mg, 10 mg).
- Suitable as an analytical reference, calibration standard, and for toxicology assays.
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Apexbio Technology LLC Clemizole hydrochloride 1163-36-6 10mM (in 1mL DMSO)
Clemizole hydrochloride is a histamine H1 receptor antagonist reported to inhibit hepatitis C virus (HCV) replication by targeting the viral NS4B protein a component essential for viral RNA replication Clemizole demonstrates antiviral activity in vitro against HCV genotype 2a subgenomic replicons exhibiting an IC50 value around 8 mM When combined with HCV protease inhibitors (such as VX950 or SCH503034) clemizole displays synergistic antiviral effects In contrast additive antiviral effects occur in combination with interferon ribavirin or polymerase inhibitors Clemizole is utilized in research contexts aimed at evaluating its efficacy potential antiviral combinations metabolism pathways and pharmacokinetics relevant to its consideration as a therapeutic candidate for HCV infection
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Medchemexpress LLC UNC9994 hydrochloride | 2108826-33-9 | 99.5% | 457.84 | 10 MG
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UNC9994 hydrochloride is a functionally selective, β-arrestin-biased dopamine D2 receptor (D2R) agonist. It selectively activates β-arrestin recruitment and signaling, demonstrating antipsychotic-like activity. It also acts as an antagonist of Gi-regulated cAMP production and a partial agonist for D2R/β-arrestin-2 interactions.
- Selectively activates β-arrestin recruitment and signaling.
- Antagonist of Gi-regulated cAMP production.
- Partial agonist for D2R/β-arrestin-2 interactions.
- Shows antipsychotic-like activity.
- Induces D2-mediated β-arrestin-2 translocation with EC50s of 6.1 nM and 448 nM.
- Acts as an antagonist at 5HT2A and 5HT2B receptors.
- Acts as an agonist at 5HT2C and 5HT1A receptors.
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eMolecules 103-90-2 | Acetaminophen | Combi-Blocks | MFCD00002328 | 151.165 | C8H9NO2 | 98.000 | CC(=O)Nc1ccc(O)cc1 | 5g | 335345644
Acetaminophen | Combi-Blocks | 103-90-2 | MFCD00002328 | 151.165 | C8H9NO2 | 98.000 | CC(=O)Nc1ccc(O)cc1 | 5g | 335345644
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Medchemexpress LLC CGP71683 hydrochloride | 192322-50-2 | MFCD07783999 | 99.4% | 512.07 g/mol | C26H30ClN5O2S | 50 MG
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CGP71683 hydrochloride is a selective, non-peptide neuropeptide Y (NPY) Y5 receptor antagonist used for in vitro pharmacology and receptor signaling studies. The compound is supplied as a white solid and as a 10 mM solution in DMSO and is reported with high purity for research applications.
- Selective NPY Y5 receptor antagonist with low nanomolar affinity.
- Reported high purity suitable for research use.
- Available as a solid and as a 10 mM solution in DMSO for assay convenience.
- Molecular weight 512.07 g/mol aiding stoichiometric calculations.
- CAS registry number 192322-50-2 for unambiguous identification.
- Intended for biochemical and pharmacological studies in vitro.
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Medchemexpress LLC HAIYPRH hydrochloride | 99.97% | 929.46 | 50 MG
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HAIYPRH hydrochloride is a targeting ligand that specifically binds to the transferrin receptor (TfR), facilitating the transport of nanocarriers across the blood-brain barrier. It is a heptapeptide investigated for targeting gliomas and enhancing cellular uptake and gene expression in co-delivery systems.
- Specifically binds to transferrin receptor (TfR).
- Mediates transport of nanocarriers across the blood-brain barrier.
- Utilized as a targeting agent for gliomas.
- Enhances cellular uptake and gene expression in co-delivery systems.
- Conjugated to liposomes for ischemic stroke targeting treatment.
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Medchemexpress LLC S-14506 hydrochloride | 286369-38-8 | 99.92% | 443.94 | 100 MG
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S-14506 hydrochloride is a potent 5-HT1A agonist and a 5-HT2A/2C antagonist. It also exhibits dopamine antagonist properties by blocking dopamine D2 receptors, inhibiting the in vivo binding of [3H]raclopride in striatum and olfactory bulbs. This compound has potential for research as an anxiolytic agent.
- Potent 5-HT1A agonist
- 5-HT2A/2C antagonist
- Exhibits dopamine D2 receptor blocking properties
- Potential for research as an anxiolytic agent
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Medchemexpress LLC LY294002 (hydrochloride) | 934389-88-5 | 99.9% | 369.8 g/mol | C19H17NO3·HCl | 5 MG
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LY294002 hydrochloride is the hydrochloride salt of LY294002, a cell-permeable small-molecule inhibitor of phosphoinositide 3-kinase (PI3K) and casein kinase 2 (CK2) used in in vitro studies of cell signaling, apoptosis, and autophagy. Supplied for research use with supporting documentation.
- Inhibits PI3K and CK2 signaling pathways.
- Suitable for in vitro cell signaling and apoptosis research.
- High purity (99.9%).
- Chemical formula C19H17NO3·HCl; molecular weight 369.8 g/mol.
- Supplied in small research quantities (e.g., 5 mg).
- Comes with SDS and certificate of analysis.
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Medchemexpress LLC ZH8659 HYDROCHLORID 25 mg
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ZH8659 HYDROCHLORID 25MG
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Medchemexpress LLC SM-164 HYDROCHLORID 100 mg
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SM-164 HYDROCHLORID 100MG
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Medchemexpress LLC FTI-277 HYDROCHLORI 1 mg
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FTI-277 HYDROCHLORI 1MG
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Medchemexpress LLC PIK-75 HYDROCHLORID 10MM 1ML
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PIK-75 HYDROCHLORID 10MM 1ML
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Medchemexpress LLC BN82002 hydrochloride | 1049740-43-3 | 99.4% | 395.88 | 10 MG
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BN82002 hydrochloride is a potent, selective, and irreversible inhibitor of the CDC25 phosphatase family. It demonstrates significant inhibitory activity against various CDC25 isoforms including CDC25A, CDC25B2, CDC25B3, CDC25C, and 25C-cat, with IC50 values ranging from 2.4 to 6.3 μM. This compound also exhibits high selectivity, showing approximately 20-fold greater inhibition over CD45 tyrosine phosphatase.
- Potent and selective CDC25 phosphatase inhibitor
- Inhibits CDC25A, CDC25B2, CDC25B3, CDC25C, and 25C-cat
- Demonstrates approximately 20-fold greater selectivity over CD45 tyrosine phosphatase
- Irreversible inhibitor
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