Aminophenols
Medchemexpress LLC Levacetylleucine (N-Acetyl-L-leucine) | 1188-21-2 | 98.0% | C8H15NO3 | 1000 G
Levacetylleucine is an orally bioavailable and brain-penetrant acetylated derivative of amino acid Leucine. It is the active form of N-acetyl-leucine (NAL), shown to attenuate neuronal death and neuroinflammation, and potentially ameliorate lysosomal and metabolic dysfunction. This compound improves compensation of postural symptoms and is promising for research into neurological manifestations of Niemann-Pick disease type C, traumatic brain injury, and neurodegeneration prevention.
- Orally bioavailable and brain-penetrant
- Attenuates neuronal death and neuroinflammation
- Potentially ameliorates lysosomal and metabolic dysfunction
- Improves compensation of postural symptoms
- Suitable for research into neurological diseases and neurodegeneration prevention
eMolecules 56621-99-9 | Ambeed | N2N2-Dimethylpyrimidine-25-diamine | 250mg | 552737660 | A497416 | MFCD11656641 | 138.174 | C6H10N4
Ambeed | N2N2-Dimethylpyrimidine-25-diamine | 250mg | 552737660 | A497416 | 56621-99-9 | MFCD11656641 | 138.174 | C6H10N4
Medchemexpress LLC CWI1-2 hydrochloride | 2408590-37-2 | C22H18Cl4N6O3 | 5 MG
CWI1-2 hydrochloride is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and shows promising anti-leukemic effects.
- IGF2BP2 inhibitor.
- Inhibits IGF2BP2 interaction with m6A-modified target transcripts.
- Induces apoptosis and differentiation.
- Demonstrates anti-leukemic effects.
- Effective in reducing Gln uptake and impairing mitochondrial function in AML cells.
- Inhibits colony-forming ability of leukemic mouse blasts.
- Impairs self-renewal of LSC/LIC.
- Delays leukemia onset and prolongs survival in vivo.
TARGETMOL CHEMICALS INC L-Azidohomoalanine hydrochlori
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 200 mg and bulk. Please contact Fisher for quotes. L-Azidohomoalanine hydrochloride (H-L-Aha-OH hydrochloride) is an alkyl chain-based PROTAC linker. Purity 98.16%
Apexbio Technology LLC 2,4-Di-tert-butylphenol 96-76-4 1g
2 4-Di-tert-butylphenol (CAS 96-76-4) is an endogenous metabolic compound recognized for its antioxidant and anti-inflammatory properties Mechanistic studies have demonstrated that 2 4-Di-tert-butylphenol modulates the expression of genes involved in apoptotic pathways leading to the induction of apoptosis in cancer cell models Additionally experimental evidence indicates antiviral and antifungal activities supporting its use in investigations of infection mechanisms This compound is therefore relevant for research in oncology inflammation and the study of pathogen-host interactions
Medchemexpress LLC HAIYPRH hydrochloride | 99.97% | 929.46 | 50 MG
HAIYPRH hydrochloride is a targeting ligand that specifically binds to the transferrin receptor (TfR), facilitating the transport of nanocarriers across the blood-brain barrier. It is a heptapeptide investigated for targeting gliomas and enhancing cellular uptake and gene expression in co-delivery systems.
- Specifically binds to transferrin receptor (TfR).
- Mediates transport of nanocarriers across the blood-brain barrier.
- Utilized as a targeting agent for gliomas.
- Enhances cellular uptake and gene expression in co-delivery systems.
- Conjugated to liposomes for ischemic stroke targeting treatment.
Medchemexpress LLC Hypidone hydrochloride | 1339058-04-6 | 99.7% | 334.84 g/mol | C18H23ClN2O2 | 100 MG
Hypidone hydrochloride is the hydrochloride salt of a research compound with potent serotonergic activity. It functions as a selective serotonin (5-HT) uptake inhibitor and a 5-HT1A receptor agonist, and has demonstrated oral activity in animal models of depression. Supplied as a powder for laboratory research use only; not for human or clinical use.
- High purity suitable for research applications.
- Dual mechanism: serotonin uptake inhibition and 5-HT1A receptor agonism.
- Demonstrated oral activity in animal depression models.
- Available in multiple pack sizes including small research quantities.
- Recommended sealed storage away from moisture; in solvent store at -80°C for long term.
Medchemexpress LLC Haiyprh hydrochloride | 268215-17-4 | 100.0% | 929.46 | 25 MG
HAIYPRH hydrochloride is a targeting ligand that specifically binds to the transferrin receptor (TfR) and can facilitate the transport of nanocarriers across the blood-brain barrier. It is also a heptapeptide used to target gliomas and is intended for research use only.
- Specifically binds to the transferrin receptor (TfR)
- Facilitates transport of nanocarriers across the blood-brain barrier
- Used to target gliomas
- Functions as a ligand for co-delivery systems to tumor cells expressing transferrin receptors
- Demonstrates higher efficiency in cellular uptake and gene expression in U87 MG cells
- Accumulates more efficiently in tumors in vivo
- Appears as a white to off-white solid
- Soluble in H2O at concentrations of 100 mg/mL or greater
Medchemexpress LLC BN82002 hydrochloride | 1049740-43-3 | 99.4% | 395.88 | 10 MG
BN82002 hydrochloride is a potent, selective, and irreversible inhibitor of the CDC25 phosphatase family. It demonstrates significant inhibitory activity against various CDC25 isoforms including CDC25A, CDC25B2, CDC25B3, CDC25C, and 25C-cat, with IC50 values ranging from 2.4 to 6.3 μM. This compound also exhibits high selectivity, showing approximately 20-fold greater inhibition over CD45 tyrosine phosphatase.
- Potent and selective CDC25 phosphatase inhibitor
- Inhibits CDC25A, CDC25B2, CDC25B3, CDC25C, and 25C-cat
- Demonstrates approximately 20-fold greater selectivity over CD45 tyrosine phosphatase
- Irreversible inhibitor
Medchemexpress LLC Pirmenol hydrochloride | 61477-94-9 | MFCD01691662 | 98.8% | 374.95 g·mol⁻¹ | C22H31ClN2O | 100 MG
Pirmenol hydrochloride is an orally active antiarrhythmic research compound used in pharmacology and electrophysiology studies. It inhibits IK.ACh currents by blocking muscarinic acetylcholine receptors and is provided as a high-purity solid for laboratory research use.
- Orally active compound suitable for cellular and in vivo studies.
- Reported to inhibit IK.ACh with IC50 ≈ 0.1 μM.
- High purity solid for reproducible experimental results.
- Available in small-quantity packages appropriate for research workflows.
- Intended for laboratory research; not for human or diagnostic use.