Aminophenols
Medchemexpress LLC NNC 92-1687 10mM 1mL | 22903-37-3 | 300.33 g·mol⁻¹ | C15H12N2O3S | 1 ML
NNC 92-1687 is a non-peptide competitive antagonist of the human glucagon receptor (GCGR) used as a research tool for studies of glucose homeostasis and type 2 diabetes. It shows IC50 = 20 μM and Ki = 9.1 μM and is supplied as a 10 mM solution in DMSO (1 mL) or as a solid.
- Non-peptide competitive glucagon receptor antagonist
- Reported IC50 of 20 μM and Ki of 9.1 μM
- Molecular formula C15H12N2O3S and molecular weight 300.33 g·mol⁻¹
- Available as 10 mM solution in DMSO (1 mL) and in multiple solid sizes
- HPLC purity approximately 98.7%
- Storage: solid at room temperature (up to 3 years); in solvent at -80°C (2 years) or -20°C (1 year)
Medchemexpress LLC 3-(benzyl(isopropyl)amino)-1-(naphthalen-2-yl)propan-1-one hydrochloride | 1021868-92-7 | MFCD04974534 | >98.0% | 367.91 g/mol | C23H26ClNO | 10MM 1ML
ZM39923 hydrochloride is a small-molecule JAK3 inhibitor used in research. It displays JAK3 potency (pIC50 = 7.1) and also inhibits tissue transglutaminase (TGM2) with an IC50 of 10 nM; it is supplied as a 10 mM solution in DMSO and in solid quantities.
- Small-molecule JAK3 inhibitor (pIC50 = 7.1).
- Potent TGM2 inhibition (IC50 = 10 nM).
- Available as 10 mM solution in DMSO and in solid forms.
- Molecular formula C23H26ClNO.
- Molecular weight 367.91 g/mol.
- Purity >98.0% by HPLC.
- For research use only.
Medchemexpress LLC HY-15743 10mg Medchemexpress, Birabresib CAS:202590-98-5 Purity:>98%
Medchemexpress, HY-15743 10mg Birabresib CAS:202590-98-5 Birabresib (OTX-015) is a potent bromodomain (BRD2/3/4) inhibitor with IC50s ranging from 92 to 112 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
![Medchemexpress LLC Benzamide, 2-chloro-5-[3-[(3-hydroxypropyl)amino]propyl]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethy-1)- | 345303-91-5 | 98.2% | 455.46 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000385590-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Benzamide, 2-chloro-5-[3-[(3-hydroxypropyl)amino]propyl]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethy-1)- | 345303-91-5 | 98.2% | 455.46 | 25 MG
AZD9056 hydrochloride is a selective and orally active inhibitor of P2X7, a receptor that plays a significant role in inflammatory and pain-causing diseases. This compound is intended for research use only.
- Blocks P2X7 receptors with an IC50 of 11.2 nM in HEK-hP2X7 cell lines, demonstrating high selectivity for the P2X7 receptor.
- Exhibits an inhibitory effect (IC50=1-3 μM) in mouse microglia BV2 cells.
- Weakly inhibits BCRP-mediated transport of methotrexate (IC50=92 μM).
- Displays pain-relieving and anti-inflammatory effects.
- Reverses the upregulated expression of interleukin (IL)-1β, IL-6, tumor necrosis factor-α (TNF-α), matrix metalloproteinase-13 (MMP-13), substance P (SP), and prostaglandin E2 (PGE2) induced by MIA in cartilage tissues.
Medchemexpress LLC AZD9056 hydrochloride | 345303-91-5 | 98.2% | 455.46 | 50 MG
AZD9056 hydrochloride is a selective orally active inhibitor of P2X7, which plays a significant role in inflammation and pain-causing diseases. It is for research use only and not sold to patients.
- Selective orally active inhibitor of P2X7.
- Blocks P2X7 receptors with an IC50 of 11.2 nM in HEK-hP2X7 cell line.
- Exhibits high selectivity for the P2X7 receptor.
- Has an inhibitory effect (IC50=1-3 μM) in mouse microglia BV2 cells.
- Weakly inhibits BCRP-mediated transport of methotrexate (IC50=92 μM).
- Exerts pain-relieving and anti-inflammatory effects in vivo.
- Reverses upregulated expression of IL-1β, IL-6, TNF-α, MMP-13, SP, and PGE2 induced by MIA in cartilage tissues.