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Filtered Search Results
Medchemexpress LLC L-phenylalanine methyl ester hydrochloride | 7524-50-7 | MFCD00012489 | 100g
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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H-Phe-OMe hydrochloride is a phenylalanine derivative[1]
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC m-PEG9-acid | 2576495-35-5 | MFCD27977514 | 98.0% | C20H40O11 | 250 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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m-PEG9-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. These compounds consist of two ligands connected by a linker, one for an E3 ubiquitin ligase and the other for a target protein, enabling the selective degradation of target proteins via the intracellular ubiquitin-proteasome system. This product is a colorless to light yellow liquid, with a molecular formula of C20H40O11 and a molecular weight of 456.53, intended for laboratory use only.
- Peg-based protac linker
- Used in the synthesis of protacs
- Enables selective degradation of target proteins
- Utilizes the intracellular ubiquitin-proteasome system
- For laboratory and research use only
- Colorless to light yellow liquid
- Purity of 98.0%
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BIOHIPPO h/m USP20 shRNA Set GFP Puro
h/m USP20 shRNA Set (GFP Puro) shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 (sh-mix) 5x10E6 (scr-mix) transducing units TU Validated human/mouse USP20 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse ubiquitin specific peptidase 20 (USP20) The shRNA has been validated to meet or exceed 70% USP20 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
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Cambridge Isotope Laboratories 1 2 3 4 6-PentaCDF (unlabeled) 25 ng/mL in nonane 0 2 mL
1 2 3 4 6-PentaCDF (unlabeled) 25 ng/mL in nonane 0 2 mL
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Medchemexpress LLC Glyoxalase I protein (mouse), His-tagged | >95.0% | 100 UG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Recombinant full-length mouse Glyoxalase I (GLO1) is a His-tagged enzyme supplied as a lyophilized powder for research use. It catalyzes conversion of methylglyoxal-glutathione adducts to S-lactoylglutathione and is provided with defined buffer formulation, quantified specific activity, and low endotoxin for biochemical assays.
- High purity (>95.0%) for reproducible enzymatic assays.
- Recombinant full-length mouse sequence representing the mature protein.
- N-terminal His tag for purification and detection.
- Measured specific activity (100.39 nmol/min/μg) for activity-based studies.
- Lyophilized in defined buffer (20 mM PB, 150 mM NaCl, pH 7.4) for stability.
- Low endotoxin level (<1 EU/μg) for sensitive applications.
- Storage guidance and reconstitution recommendations provided to preserve activity.
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Medchemexpress LLC Galectin-3/LGALS3 M 5ug | 5ug
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Galectin-3/LGALS3 protein binds IgE and cooperates with integrins -3 and -1 to promote endothelial cell migration It contributes to epithelial cell differentiation and acts as a splicing factor in the nucleus Galectin-3/LGALS3 Protein Mouse (HEK293 His) is the recombinant mouse-derived Galectin-3/LGALS3 protein expressed by HEK293 with C-His labeled tag
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Cayman Chemical 2-Methoxy-4-methylphenol 50g
A phenolic pyrolysis product of plant biomass; a volatile component of black olives and roasted coffee beans
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Cambridge Isotope Laboratories 1 8-DiCN (PCN-9) (13C10 99%) 10 ug/mL in isooctane 1 2 mL
1 8-DiCN (PCN-9) (13C10 99%) 10 ug/mL in isooctane 1 2 mL
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Medchemexpress LLC M-PEG17-acid | 2346581-96-0 | 98.5% | C36H72O19 | 50 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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m-PEG17-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein.
- Exploits the intracellular ubiquitin-proteasome system.
- Selectively degrades target proteins.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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BIOHIPPO h/m MCL1-sh-BSD
h/m MCL1-sh-BSD shRNA lentiviral vector expressing with Blasticidin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated human/mouse MCL1 shRNA lentivirus High-titer shRNA lentiviral particles specific for human/mouse MCL1 apoptosis regulator BCL2 family member (MCL1) The shRNA has been validated to meet or exceed 70% MCL1 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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BIOHIPPO TetOn h/m HIF1a-sh-Puro
TetOn h/m HIF1a-sh-Puro shRNA lentiviral vector expressing with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 2x10E6 transducing units TU Validated HIF1a shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse hypoxia inducible factor 1 subunit alpha (HIF1a) The shRNA has been validated to meet or exceed 70% HIF1a knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Cambridge Isotope Laboratories 1 2 3 4 6 7-HexaCDD (unlabeled) 25 ng/mL in nonane 0 2 mL
1 2 3 4 6 7-HexaCDD (unlabeled) 25 ng/mL in nonane 0 2 mL
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Apexbio Technology LLC EZ Cap Mouse IL-36γ mRNA (m1Ψ HA tag) 1mg (1mg/mL)
Mouse IL-36 mRNA encodes cytokine interleukin-36 (IL-36)Gamma primarily involved in inflammatory responses and immune regulation IL-36 acts through binding to the IL-36 receptor activating downstream signaling pathways like NF- B and MAPK promoting the release of inflammatory cytokines and activation of immune cells IL-36 is involved in multiple inflammatory disorders including psoriasis inflammatory bowel diseases and rheumatoid arthritis IL-36 may have pro-inflammatory functions in the pathological processes of these diseases making it a potential therapeutic target EZ Cap Mouse IL-36 mRNA (m1 HA tag) is supplied at 1 mg/mL It expresses mouse IL-36 cytokine fused with an HA tag facilitating subsequent detection With cap 1 structure generated through co-transcriptional capping incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC m-PEG7-CH2CH2COOH | 1093647-41-6 | 10 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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m-PEG7-CH2CH2COOH is a non-cleavable ADC linker utilized in the creation of antibody-drug conjugates (ADCs). It also serves as a PEG-based PROTAC linker for the synthesis of PROTACs. ADCs consist of an antibody linked to an ADC cytotoxin via an ADC linker. PROTACs feature two distinct ligands connected by a linker: one targets an E3 ubiquitin ligase, and the other binds to the target protein. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Non-cleavable linker for antibody-drug conjugates
- PEG-based linker for PROTACs
- Exploits the ubiquitin-proteasome system
- Designed for selective degradation of target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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TARGETMOL CHEMICALS INC S-PF-06873600 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. (S)-PF-06873600 is the S enantiomer of PF-06873600 which is an inhibitor of CDK. purity: 98%
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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