Cresols
Apexbio Technology LLC p-Cresyl sulfate potassium 91978-69-7 100mg
p-Cresyl sulfate potassium (CAS 91978-69-7) is the potassium salt form of p-cresyl sulfate a metabolite that accumulates as a protein-bound uremic toxin in patients with chronic kidney disease Biologically it exerts proinflammatory effects by activating cellular signaling pathways including c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK) which can enhance inflammatory responses Research indicates that p-cresyl sulfate potassium also contributes to cardiovascular risk by adversely impacting vascular and cardiac function This compound is utilized in experimental studies investigating the molecular mechanisms of uremic toxicity inflammation and cardiorenal syndromes
Medchemexpress LLC Atrial natriuretic peptide (1-28), human, porcine, biotin-labeled | 1815618-06-4 | 99.43% | 3308.80 | 10 MG
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, is one of three mammalian natriuretic peptides (NPs), which has endocrine effects on fluid homeostasis and blood pressure. This peptide has potential for cardiovascular diseases research.
- Has endocrine effects on fluid homeostasis and blood pressure
- Potential for cardiovascular diseases research
- One of three mammalian natriuretic peptides (NPs)
- Related to peptide and derivatives, hormones and neuropeptides
- Relevant for blood or cardio-cerebrovascular disease, metabolic or endocrine disease, endocrinology, cardiovascular disease
- Fluorescent dye
- Functions as an inhibitor
Medchemexpress LLC Interleukin-13 (mouse) | 50UG
Recombinant animal-free mouse interleukin-13 with a C-terminal His tag, expressed in E. coli and supplied lyophilized. The preparation is endotoxin-controlled and biologically active, suitable for cell-based assays (for example, TF-1 proliferation) and biochemical studies that require low-endotoxin cytokine preparations.
- Animal-free recombinant protein suitable for in vitro assays.
- His-tag for easy purification and detection.
- Low endotoxin (<0.1 EU/μg) for sensitive applications.
- Biologically active: ED50 <10 ng/mL in TF-1 proliferation assay.
- High specific activity (>2.5x10^5 IU/mg).
- Lyophilized from PBS for stability and handling convenience.
- Approximate molecular weight ~11 kDa.
- Recommended reconstitution at 100-200 μg/mL; store at -20°C.
eMolecules Ambeed / Isobutyl 5-(25-dimethylphenoxy)-22-dimethylpentanoate / 5g / 779704306 / A748966 / / 149105-26-0 / MFCD08704557 / 306.446 / C19H30O3
Ambeed / Isobutyl 5-(25-dimethylphenoxy)-22-dimethylpentanoate / 5g / 779704306 / A748966 / / 149105-26-0 / MFCD08704557 / 306.446 / C19H30O3
BIOHIPPO h/m FGF17 shRNA Set GFP Puro
h/m FGF17 shRNA Set (GFP Puro) shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 (sh-mix) 5x10E6 (scr-mix) transducing units TU Validated h/m FGF17 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse fibroblast growth factor 17 (FGF17) The shRNA has been validated to meet or exceed 70% knockdown of FGF17 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
BIOHIPPO h/m NRP1-sh-GFP/Luc
h/m NRP1-sh-GFP/Luc shRNA lentiviral vector expressing GFP/Luc with selection for studies in Human/Mouse Each vial provides a nominal titer of 2x10E6 transducing units TU Validated h/m NRP1 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse neuropilin 1 (NRP1) The shRNA has been validated to meet or exceed 70% knockdown of NRP1 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Medchemexpress LLC 2OH-BNPP1 | 833481-73-5 | MFCD28120704 | 99.7% | 297.35 g/mol | C16H19N5O | 50 MG
2OH-BNPP1 is a small-molecule inhibitor of BUB1 serine/threonine kinase used in cancer research to probe mitotic checkpoint signaling and cell-cycle regulation. The compound is supplied as a solid for laboratory research use.
- Inhibits BUB1 kinase, a serine/threonine kinase implicated in mitosis.
- High purity suitable for biochemical and cell-based assays.
- Soluble in DMSO; in vivo formulation examples are reported.
- Available in milligram-scale quantities including 50 mg.
- Powder storage at low temperature recommended for long-term stability.
Medchemexpress LLC AMG-108 1mg | 1mg
AMG-108 is a humanized antibody expressed in CHO cells targeting IL-1R1/CD121a AMG-108 is composed of a huIgG2 heavy chain and a hu light chain with a predicted molecular weight (MW) of 144 62 kDa The isotype control for AMG-108 can refer to Human IgG2 kappa Isotype Control (HY-P99002)
Medchemexpress LLC Azoreductase/NQO1 M 5ug
Recombinant mouse Azoreductase/NQO1 enzyme expressed in Pichia pastoris with an N-terminal 6xHis tag, supplied lyophilized and formulated to preserve activity. The protein catalyzes two-electron reduction of quinones using NADH or NADPH and is suitable for biochemical assays, enzymology, and cellular redox studies.
- Recombinant mouse enzyme expressed in Pichia pastoris.
- N-terminal 6xHis tag for purification and detection.
- Lyophilized formulation for extended shelf life and transport.
- Purity greater than 90% by reducing SDS-PAGE for consistent performance.
- Suitable for biochemical assays, kinetic studies, and redox research.
- Stable when stored frozen; follow reconstitution and storage guidance.