Cresols
![eMolecules 2055839-77-3 | 1-{3-hydroxybicyclo[1.1.1]pentan-1-yl}ethan-1-one | Pharmablock | MFCD30530452 | 126.155 | C7H10O2 | 97.000 | CC(=O)C12CC(O)(C1)C2 | 5g | 551314731](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000161810.jpg-250.jpg)
eMolecules 2055839-77-3 | 1-{3-hydroxybicyclo[1.1.1]pentan-1-yl}ethan-1-one | Pharmablock | MFCD30530452 | 126.155 | C7H10O2 | 97.000 | CC(=O)C12CC(O)(C1)C2 | 5g | 551314731
1-{3-hydroxybicyclo[1.1.1]pentan-1-yl}ethan-1-one | Pharmablock | 2055839-77-3 | MFCD30530452 | 126.155 | C7H10O2 | 97.000 | CC(=O)C12CC(O)(C1)C2 | 5g | 551314731
Medchemexpress LLC Atrial natriuretic peptide (1-28), human, porcine, biotin-labeled | 1815618-06-4 | 99.43% | 3308.80 | 10 MG
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, is one of three mammalian natriuretic peptides (NPs), which has endocrine effects on fluid homeostasis and blood pressure. This peptide has potential for cardiovascular diseases research.
- Has endocrine effects on fluid homeostasis and blood pressure
- Potential for cardiovascular diseases research
- One of three mammalian natriuretic peptides (NPs)
- Related to peptide and derivatives, hormones and neuropeptides
- Relevant for blood or cardio-cerebrovascular disease, metabolic or endocrine disease, endocrinology, cardiovascular disease
- Fluorescent dye
- Functions as an inhibitor
Medchemexpress LLC N-(p-Coumaroyl) Serotonin | 68573-24-0 | 99.0% | 50 MG
N-(p-Coumaroyl) Serotonin is a selective inhibitor of PDGFRβ, ERK1/2, and caspase-8, exhibiting antioxidant, anti-atherosclerotic, and anti-inflammatory properties. It inhibits glioblastoma cells and demonstrates anti-inflammatory activity in RAW264.7 cells. The compound works by inhibiting PDGF signaling, blocking Ca2+ influx, and inducing apoptosis, making it suitable for glioblastoma and atherosclerosis research.
- Selective inhibitor of PDGFRβ, ERK1/2, and caspase-8
- Possesses antioxidant, anti-atherosclerotic, and anti-inflammatory properties
- Inhibits glioblastoma cells
- Reduces PDGF signaling and blocks Ca2+ influx
- Induces apoptosis through caspase-8 activation
- Improves atherosclerosis and aortic wall enlargement
Medchemexpress LLC NPR2 Human P. past 2ug
NPR2 Protein Human (P pastoris His) serves as the receptor for C-type natriuretic peptide NPPC/CNP activating guanylate cyclase upon ligand binding NPR2 potentially regulates skeletal growth indicating involvement in bone development Its interaction with C-type natriuretic peptide highlights its significance in mediating cellular responses especially in signaling pathways influencing skeletal growth dynamics NPR2 Protein Human (P pastoris His) is the recombinant human-derived Atrial natriuretic peptide receptor 2/NPR2 expressed by P pastoris with N-His labeled tag
Medchemexpress LLC NY-ESO-1 (157-165) peptide TFA | 97.6% | 1208.37 | 10 MG
NY-ESO-1 (157-165) peptide (TFA) is a peptide fragment from the NY-ESO-1 protein. It can activate the immune system, particularly in HLA-A2 positive individuals, by being recognized by CD8+ T cells, thereby triggering an immune response. This peptide is expressed in various tumors and can be utilized as a target for tumor immunotherapy.
- Peptide fragment from NY-ESO-1 protein
- Activates the immune system in HLA-A2 positive individuals
- Recognized by CD8+ T cells, triggering an immune response
- Expressed in various tumors
- Can be used as a target for tumor immunotherapy
- Highly immunogenic epitope of NY-ESO-1
- Can induce spontaneous or vaccine-induced T cell immune responses
Medchemexpress LLC P 22077 | 1247819-59-5 | 98.4% | 315.32 | 50 MG
P 22077 is a cell-permeable ubiquitin-specific protease 7 (USP7) inhibitor with an EC50 of 8.01 μM. It also inhibits USP47 with an EC50 of 8.74 μM.
- USP7 inhibitor (EC50: 8.01 μM)
- USP47 inhibitor (EC50: 8.74 μM)
- Cell-permeable
- Inhibits a smaller subset of DUBs at 15-45 μM
- Causes DUBs inhibition in HEK293T cells at 25 μM
- Greatly reduces cell viability of neuroblastoma (NB) cells
- Increases p53 activity and induces apoptosis in p53 wild-type and HDM2-expressing NB cells at 10 μM
- Enhances cytotoxic effect of Dox and VP-16 on NB cells, and enhances Dox- and VP-16-induced p53-mediated apoptosis at 5 μM
- Shows potent antitumor activities in xenograft mouse models bearing IMR-32-derived tumors
- Exhibits antitumor effects in mice bearing SH-SY5Y-derived tumors and NGP-derived tumors
Medchemexpress LLC Lys(CO-C3-p-I-Ph)-OMe | 2088426-96-2 | 97.2% | 432.30 g/mol | C17H25IN2O3 | 10 MG
Lys(CO-C3-p-I-Ph)-OMe is a pharmacokinetic modifier used in research to improve the pharmacokinetic properties of PSMA-targeting ligands, including increased plasma residence time and altered tissue uptake. It is supplied in purified powder and solution formats suitable for preclinical studies.
- Improves plasma residence time of PSMA ligands.
- Increases albumin binding to extend circulation half-life.
- Reduces off-target salivary gland uptake of modified ligands.
- Available as powder in multiple mg sizes and as 10 mM solution in DMSO.
- High purity suitable for research applications.
Medchemexpress LLC P-Selectin Rat HEK 50ug
P-Selectin a Ca(2 )-dependent receptor on myeloid cells binds to neutrophils and monocytes via carbohydrates It interacts with SELPLG to enable rapid leukocyte rolling over vascular surfaces in early inflammation P-Selectin also interacts with SNX17 and promotes neutrophil adhesion and rolling requiring SELPLG s sialyl-Lewis X and tyrosine sulfation P-Selectin Protein Rat (HEK293 His) is the recombinant rat-derived P-Selectin protein expressed by HEK293 with C-His labeled tag
Cambridge Isotope Laboratories p-n-Nonylphenol (unlabeled) 100 ug/mL in nonane 1 2 mL
p-n-Nonylphenol (unlabeled) 100 ug/mL in nonane 1 2 mL
Medchemexpress LLC P 22077 | 1247819-59-5 | 98.42% | 315.32 | 100 MG
P 22077 is a cell-permeable ubiquitin-specific protease 7 (USP7) inhibitor, also inhibiting USP47. It causes DUBs inhibition in HEK293T cells and significantly reduces the viability of Neuroblastoma (NB) cells. P 22077 increases p53 activity, inducing apoptosis in p53 wild-type and HDM2-expressing NB cells, and enhances the cytotoxic effects of Dox and VP-16. In vivo, it exhibits potent antitumor activities in xenograft mouse models.
- Cell-permeable ubiquitin-specific protease 7 (USP7) inhibitor
- Also inhibits USP47
- Reduces neuroblastoma cell viability
- Increases p53 activity and induces apoptosis
- Enhances Dox and VP-16 cytotoxic effects
- Demonstrates potent antitumor activities in mouse models
Medchemexpress LLC P-hydroxybenzaldehyde-d4 | 284474-52-8 | 99.7% | 126.15 | C7H2D4O2 | 10mg
p-Hydroxybenzaldehyde-d4 is the deuterium labeled p-Hydroxybenzaldehyde p-Hydroxybenzaldehyde is a one of the major components in Dendrocalamus asper bamboo shoots with antagonistic effect on GABAA receptor of the 1 2 2S subtype at high concentrations
Medchemexpress LLC 4-Chloro-2-methylphenol-d4 (4-chloro-o-cresol-d4) | 1219804-06-4 | 99.6% | 146.61 | 50 MG
4-Chloro-2-methylphenol-d4 is a deuterium-labeled version of 4-Chloro-2-methylphenol. It is intended for research use only and is not sold to patients. This compound can be used as a tracer and as an internal standard for quantitative analysis by methods such as NMR, GC-MS, or LC-MS. Deuterium substitution, as seen in this compound, has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Functions as an internal standard for quantitative analysis.
- Stable heavy isotope.
Medchemexpress LLC 3-(2-Pyridyldithio)propanoic Acid | 68617-64-1 | 99.5% | 25 G
3-(2-Pyridyldithio)propanoic Acid is an alkyl chain-based PROTAC linker used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting two ligands: one for an E3 ubiquitin ligase and another for the target protein.
- Alkyl chain-based PROTAC linker
- Used in the synthesis of PROTACs
- Utilizes the ubiquitin-proteasome system
- Selectively degrades target proteins
eMolecules 123-11-5 | p-Anisaldehyde | Chem-Impex | MFCD00003385 | 136.150 | C8H8O2 | 98.000 | COc1ccc(C=O)cc1 | 25g | 490847545
p-Anisaldehyde | Chem-Impex | 123-11-5 | MFCD00003385 | 136.150 | C8H8O2 | 98.000 | COc1ccc(C=O)cc1 | 25g | 490847545
Medchemexpress LLC [D-p-Cl-Phe6,Leu17]-VIP TFA | 98.16% | 3456.22 | 10 MG
[D-p-Cl-Phe6,Leu17]-VIP TFA is a competitive and selective antagonist of vasoactive intestinal peptide (VIP) receptor, with an IC50 of 125.8 nM. It shows no activity on glucagon, secretin, or GRF receptors.
- Competitive and selective antagonist of VIP receptor
- IC50 of 125.8 nM against VIP receptor
- No activity on glucagon, secretin, or GRF receptors