Cresols
Cambridge Isotope Laboratories p-n-Nonylphenol diethoxylate (unlabeled) 500 ug/mL in acetonitrile 1 2 mL
p-n-Nonylphenol diethoxylate (unlabeled) 500 ug/mL in acetonitrile 1 2 mL
Medchemexpress LLC Calmodulin Binding Peptide 1 | 104041-80-7 | 98.7% | 5301.10 | 25 MG
Calmodulin Binding Peptide 1 is a high-affinity (pM) CaM-binding peptide derived from smooth muscle myosin light chain kinase (MLCK peptide). The interface of the complex formed by Calmodulin Binding Peptide 1 and Ca2+-CaM can be specifically bound by small-molecule inhibitors, serving as a key target for selective regulation of smooth muscle contraction and development of anti-CaM drugs.
- High-affinity (pM) CaM-binding peptide.
- Derived from smooth muscle myosin light chain kinase (MLCK peptide).
- The complex with Ca2+-CaM can be specifically bound by small-molecule inhibitors.
- Serves as a key target for selective regulation of smooth muscle contraction.
- Used for the development of anti-CaM drugs.
- Binds to the human calmodulin fluorescent biosensor hCaM M124C-mBBr with high affinity (Kd = 2.55 ± 1.75 pM) in vitro.
- Can displace the lower-affinity inhibitor MBC from the biosensor.
Medchemexpress LLC Substance P(1-7) TFA | 2828433-22-1 | 99.1% | 1014.06 | 25 MG
Substance P(1-7) TFA is a fragment of the neuropeptide, substance P (SP). It gives depressor and bradycardic effects when applied to the nucleus tractus solitarius. Substance P(1-7) is found to act as a very potent antagonist against the SP-induced responses and is formed locally in the nigra after SP injection. It is proposed that Substance P(1-7) is an endogenous modulator of SP actions. For research use only.
- Fragment of neuropeptide, Substance P (SP)
- Acts as a potent antagonist against SP-induced responses
- Exhibits depressor and bradycardic effects
- Modulates actions of SP or SP(5-11) in the spinal cord
- For research use only
Medchemexpress LLC TL02-59 | 1315330-17-6 | 99.9% | 609.64 | 1 MG
TL02-59 is an orally active, selective Src-family kinase Fgr inhibitor with an IC50 of 0.03 nM. It also inhibits Lyn and Hck with IC50s of 0.1 nM and 160 nM, respectively. It is known to potently suppress acute myelogenous leukemia (AML) cell growth.
- Orally active, selective Src-family kinase Fgr inhibitor
- Inhibits Lyn and Hck
- Potently suppresses acute myelogenous leukemia (AML) cell growth
- Inhibits Fgr autophosphorylation in TF-1 cells
- Induces growth arrest in primary AML bone marrow samples
- Eliminates AML cells from the spleen and peripheral blood in a mouse model of AML
- Potential therapeutic agent for acute myelogenous leukemia (AML)
eMolecules 1613373-40-2 | 1-(4-bromo-3,5-dimethylphenyl)-5,5-dimethylimidazolidine-2,4-dione | Advanced ChemBlocks | MFCD30803364 | 311.179 | C13H15BrN2O2 | 95.000 | Cc1cc(cc(C)c1Br)N1C(=O)NC(=O)C1(C)C | 1g | 784393395
1-(4-bromo-3,5-dimethylphenyl)-5,5-dimethylimidazolidine-2,4-dione | Advanced ChemBlocks | 1613373-40-2 | MFCD30803364 | 311.179 | C13H15BrN2O2 | 95.000 | Cc1cc(cc(C)c1Br)N1C(=O)NC(=O)C1(C)C | 1g | 784393395