Cresols
Sigma Aldrich Fine Chemicals Biosciences m-Cresol >=98%, FG | 108-39-4 | MFCD00002302 | 25KG
m-Cresol >=98%, FG | Purity: >=98% | Mol Wt: 108.14 | 108-39-4 | MFCD00002302 | 25KG
Sigma Aldrich Fine Chemicals Biosciences o-Cresol >=99% | 95-48-7 | MFCD00002226 |
o-Cresol >=99% | Purity: >=99% | Mol Wt: 108.14 | 95-48-7 | MFCD00002226 |
Sigma Aldrich Fine Chemicals Biosciences o-Cresol >=99% | 95-48-7 | MFCD00002226 | 25KG
o-Cresol >=99% | Purity: >=99% | Mol Wt: 108.14 | 95-48-7 | MFCD00002226 | 25KG
Sigma Aldrich Fine Chemicals Biosciences 2,5-Dimethylphenol >=99% | 95-87-4 | MFCD00002237 | 5G
2,5-Dimethylphenol >=99% | Purity: >=99% | Mol Wt: 122.16 | 95-87-4 | MFCD00002237 | 5G
Sigma Aldrich Fine Chemicals Biosciences p-Cresol >=99%, FG | 106-44-5 | MFCD00002376 |
p-Cresol >=99%, FG | Purity: >=99% | Mol Wt: 108.14 | 106-44-5 | MFCD00002376 |
Sigma Aldrich Fine Chemicals Biosciences p-Cresol >=99%, FG | 106-44-5 | MFCD00002376 | 1KG
p-Cresol >=99%, FG | Purity: >=99% | Mol Wt: 108.14 | 106-44-5 | MFCD00002376 | 1KG
Sigma Aldrich Fine Chemicals Biosciences p-Cresol >=99%, FG | 106-44-5 | MFCD00002376 | 10KG
p-Cresol >=99%, FG | Purity: >=99% | Mol Wt: 108.14 | 106-44-5 | MFCD00002376 | 10KG
Apexbio Technology LLC p-Cresyl sulfate potassium 91978-69-7 100mg
p-Cresyl sulfate potassium (CAS 91978-69-7) is the potassium salt form of p-cresyl sulfate a metabolite that accumulates as a protein-bound uremic toxin in patients with chronic kidney disease Biologically it exerts proinflammatory effects by activating cellular signaling pathways including c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK) which can enhance inflammatory responses Research indicates that p-cresyl sulfate potassium also contributes to cardiovascular risk by adversely impacting vascular and cardiac function This compound is utilized in experimental studies investigating the molecular mechanisms of uremic toxicity inflammation and cardiorenal syndromes
Apexbio Technology LLC Recombinant Mouse M-CSF/CSF1 10ug
Recombinant Mouse M-CSF CSF1 is a recombinant protein targeting the macrophage colony stimulating factor receptor (c-FMS) It is designed to regulate survival growth and differentiation of macrophages and support proliferation and viability of osteoclast precursor cells by modulating macrophage-related biological processes Recombinant Mouse M-CSF CSF1 exerts its biological activity primarily through binding to c-FMS inducing receptor-mediated endocytosis chemotactic signaling and modulation of macrophage functions such as cytokine secretion cytotoxicity and phagocytosis Based on these pharmacological properties Recombinant Mouse M-CSF CSF1 holds research potential in macrophage biology inflammation osteoclastogenesis immune responses and developmental biology
Apexbio Technology LLC Ansamitocin P-3 66547-09-9 5mg
Ansamitocin P-3 (CAS 66547-09-9) is a small-molecule inhibitor targeting tubulin It is designed to disrupt microtubule assembly by potently inhibiting tubulin polymerization thereby affecting cellular processes reliant on microtubule dynamics Ansamitocin P-3 exerts its biological activity primarily through inhibition of tubulin polymerization In cell-based studies Ansamitocin P-3 demonstrates cytotoxicity with IC50 values of approximately 4 10 g/ml in human lung carcinoma A-549 and colon carcinoma HT-29 cells and 2 10 g/ml in breast carcinoma MCF-7 cells Additionally it inhibits ciliary regeneration in Tetrahymena cells at concentrations around 1 M Based on these pharmacological properties Ansamitocin P-3 holds research potential in oncology particularly in studies of microtubule dynamics anticancer drug mechanisms and ciliogenesis
Apexbio Technology LLC Ansamitocin P-3 66547-09-9 50mg
Ansamitocin P-3 (CAS 66547-09-9) is a small-molecule inhibitor targeting tubulin It is designed to disrupt microtubule assembly by potently inhibiting tubulin polymerization thereby affecting cellular processes reliant on microtubule dynamics Ansamitocin P-3 exerts its biological activity primarily through inhibition of tubulin polymerization In cell-based studies Ansamitocin P-3 demonstrates cytotoxicity with IC50 values of approximately 4 10 g/ml in human lung carcinoma A-549 and colon carcinoma HT-29 cells and 2 10 g/ml in breast carcinoma MCF-7 cells Additionally it inhibits ciliary regeneration in Tetrahymena cells at concentrations around 1 M Based on these pharmacological properties Ansamitocin P-3 holds research potential in oncology particularly in studies of microtubule dynamics anticancer drug mechanisms and ciliogenesis
Apexbio Technology LLC P 22077 1247819-59-5 10mg
P 22077 (CAS 1247819-59-5) is a small molecule inhibitor targeting ubiquitin-specific protease 7 (USP7 also known as HAUSP) and to a lesser extent deubiquitinase USP4 USP7 modulates the stability of several regulatory proteins including p53 impacting apoptosis pathways in cancer biology P 22077 demonstrates potent USP7 inhibition with IC values of 8 6 nM in singleplex and 7 8 nM in multiplex in vitro assays and shows minimal activity against related enzymes DEN1 and SENP2core Cellular studies suggest that P 22077-mediated USP7 inhibition destabilizes Tip60 attenuating p53-dependent apoptosis The compound is currently utilized in preclinical research investigating the role of deubiquitination in tumorigenesis
Apexbio Technology LLC DiscoveryProbe™ Anti-infection Compound Library Plus 100uL/well(10 mM solution),96 Well Deep Well Plate
DiscoveryProbe Anti-infection Compound Library comprises 367 bioactive small-molecule compounds with demonstrated anti-infective activities against bacterial viral fungal or parasitic pathogens Compounds selected have documented mechanisms of action covering inhibition of pathogenic replication interference with cell wall synthesis disruption of membrane integrity and modulation of microbial-specific metabolic pathways Many included agents have been clinically approved by FDA or EMA aiding translational research efforts Representative compounds such as fluconazole azithromycin ribavirin and mebendazole are encompassed The library provides a relevant tool for bio-pharmaceutical researchers conducting high-throughput screening assays mechanistic studies and identification of novel therapeutic approaches in infectious disease characterization and anti-infective drug discovery
Apexbio Technology LLC Recombinant Mouse M-CSF 500ug
Macrophage Colony-Stimulating Factor (M-CSF) also known as CSF-1 is a hematopoietic cytokine involved in regulating proliferation differentiation and survival of monocyte/macrophage lineage cells through binding to its receptor CSF1R Belonging to the four-alpha-helix bundle cytokine family biologically active M-CSF functions primarily as a disulfide-linked homodimer Mouse M-CSF shares approximately 81 87% sequence identity with human rat canine and bovine homologs across its mature form Recombinant Mouse M-CSF (e g Mus musculus M-CSF UniProt P07141 fragment Glu33-Arg262) expressed in E coli as a tag-free protein is commonly utilized in biomedical studies to investigate monocyte/macrophage differentiation inflammation mechanisms and bone metabolism
Chem-Impex International, Inc. 3-Hydroxy-2-methylbenzoic acid | MFCD00671541 | 25G
3-Hydroxy-2-methylbenzoic acid, MFCD00671541, 25G